Int J Neuropsychopharmacol. 2006 Eprel; 9 (2): 221-8 . Epub 2005 Jun 28.
Kim SJ, Lyoo IK, Hwang J, Chung A, Hoon Sung Y, Kim J, Kwon DH, Chang KH, Renshaw PF.
Source
Gil Medical Center, Gachon Medical School, Department of Psychiatry, Incheon, South Korea.
nkịtị
Ndị ode akwụkwọ nyochara njupụta isi awọ n'ime ndị mmejọ methamphetamine 29 yana ihe ntụnyere 20 ahụike na-eji morphometry dabere na voxel. Atụnyere mgbanwe njupụta isi awọ na arụmọrụ na Wisconsin Card Sorting test (WCST) n'etiti 11 mkpụmkpụ-oge (<6 ọnwa) na 18 ogologo oge (>ma ọ bụ = 6 ọnwa) abstinent methamphetamine mmegbu. Ndị na-emetọ methamphetamine nwere njupụta isi awọ dị ala na cortex dị n'etiti aka nri (nke emeziri p<0.05) yana mmejọ ndị ọzọ na WCST (p <0.01) metụtara isiokwu ntụnyere ahụike. Mbelata ihe isi awọ na cortex dị n'etiti aka nri jikọtara ya na mperi zuru oke na WCST na ndị na-emetọ methamphetamine (r=-0.45). Ndị na-emegbu ndị na-eme ihe ike ogologo oge nwere obere mbelata njupụta n'ihu ihu isi awọ (p<0.01) na nrụrụ aka zuru oke na WCST (p<0.01) karịa ndị mmegbu na-adịghị adịte aka, mana karịa ihe atụnyere ahụike. Anyị na-akọ na ndị na-emetọ methamphetamine nwere ụkọ isi awọ nke prefrontal, nke nwere ike, n'otu akụkụ, gbakee site na abstinence ogologo oge.
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