Biol Psychiatry. 2007 Feb 1; 61 (3): 396-404. Epub 2006 Nov 9.
Sareen J, Campbell DW, Leslie WD, Malisza KL, Stein MB, Paulus MP, Kravetsky LB, Kjernisted KD, Walker JR, Reiss JP.
Source
Ngalaba isi mgbaka, Mahadum Manitoba, Winnipeg, Canada. [email protected]
nkịtị
MGBE:
Ọ bụ ezie na ihe akaebe na-egosi itinye aka nke amygdala na phobia mmekọrịta ọha na eze (GSP), ọmụmụ ole na ole nyochara mpaghara ndị ọzọ dị egwu. Clinical, prelinical, na dopamine na-ese ihe ọmụmụ na-egosipụta ịgbanwee dopaminergic ọrụ na GSP na-atụ aro mkpakọrịta na disatal dysfunction. Nke a bụ ihe ọmụmụ izizi ikike ndọta ihe (fMRI) iji rụọ ọrụ amamịghe amaara ama wee tinye ya na iji mee nyocha ihe gbasara GSP.. Anyị nyochara ma isiokwu ndị nwere GSP nwere ikike dị iche na mpaghara ọkụ ma e jiri ya tụnyere isiokwu nchịkwa ahụike ka anyị na-arụ ọrụ ọgụgụ isi egosipụtara iji rụọ ọrụ mpaghara ike ịdabere.
METHODS:
Ndi okenye iri, ndi edozighi ha nke nwere udiri ihe omimi nke DSM-IV nke GSP na 10-, okike-, na mmuta ya nyere ihe omumu nke oma banyere FMRI ka ha na eme oru izi ihe doro anya.
IHE:
Ndị GSP na ndị ntụnyere ahụike enweghị ọdịiche dị ukwuu na arụmọrụ omume nke ọrụ ahụ. Isi okwu nke GSP nwere, belatara mmezi neural na aru oru metụtara mmụta doro anya ma e jiri ya tụnyere isi mgbakwunye ekpe, isi nchịkwa aka ekpe, na nkwanye ugwu.
Nkwenye:
Nchọpụta ndị a na-akwado echiche nke GSP nwere njikọ na dysfunction striatal ma nwekwuo nghọta neurobiological nke nsogbu ụjọ a dị mgbagwoju anya.
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