Ọrịa uche. 2016 Jun 2; 254: 10-17. doi: 10.1016 / j.pscychresns.2016.05.006.
Bae S1, Han DH2, Kim SM3, Shi X4, Renshaw PF4.
nkịtị
Ọmụmụ ihe ọmụmụ gara aga nyochara mmekọrịta nke mgbanwe metabolic ụbụrụ na ndị ọrịa nwere nlebara anya hyperactivity aghara (ADHD) na ọgba aghara egwuregwu ịntanetị (IGD). Agbanyeghị, ụmụ akwụkwọ ndị amabeghị, ọmụmụ ihe buru ibu na afọ ọmụmụ, na mpaghara ụbụrụ dị iche iche nwere mmachi. Ọmụmụ ihe ọmụmụ a nyochara nsonaazụ egwuregwu egwuregwu ịntanetị na-adịghị ala ala na ụmụaka ADHD. Afọ iri asatọ na asatọ ADHD dị afọ iri na ụma nwere IGD (IGD + ADHD), ụmụ ntorobịa 27 ADHD na-enweghị egwuregwu ịntanetị na-enwe nsogbu (ADHD naanị) yana ndị ntorobịa ntụnyere ahụike (HC) gụnyere. Emere ndọtị elektrik ndọtị (MRS) na nyocha 42T MRI. Nsonaazụ anyị na-egosi na ọkwa nke NAA na otu ADHD abụọ dị ala karịa nke a hụrụ na otu HC. A mụbara ọkwa Glu + Gln na ADHD naanị otu, ma e jiri ya tụnyere ndị a hụrụ na otu ndị na-ahụ maka njikwa. Agbanyeghị, Glu + Gln enweghị ụba na IGD + ADHD otu. Na mgbakwunye, ọkwa Glu + Gln nọ na IGD + ADHD otu dabara na ngụkọta K-ARS na akara inattention. Egosiputara ADHD na IGD ihe omimi site na ọkwa NAA belata n'ime oghere ihu ya, na-agbanwe agbanwe na hypofrontality.
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AKWỤKWỌ:
Ntị mmebi ọghe hyperactivity; Glutamate + na-egbu egbu; Magnetik resonance spectroscopy; N-acetylaspartate