Nkwụsị Brain. 2013 Dec 6;1541:22-32. doi: 10.1016/j.brainres.2013.10.015.
Garduño-Gutiérrez R1, León-Olea M, Rodríguez-Manzo G.
nkịtị
Ndị na-anabata opioid na-enyocha ngwa mkpali agonist ụfọdụ. Ihe omumu ihe di omimi banyere nnabata obula anabatabeghi nke oma, nihi nihi na oke vidiyo n’usoro eji eme ihe omumu a. Ejaculation na-akwalite mwepu opioid endogenous nke na-eme ka ndị na-anabata opioid na ụbụrụ, gụnyere sistem mesolimbic na mpaghara ntụgharị uche nke medial. Ebumnuche nke ọrụ dị ugbu a bụ ịtụle ma ọ bụrụ na enwere mmekọrịta n'etiti ogo nke in vivo mu (MOR) na delta opioid receptor (DOR) na mpaghara ventral tegmental na mmeju nke ụdị ejaculatory omume nke ụmụ oke. Ebumnuche a, anyị nyochara ụbụrụ oke nke na-ewepụta otu ugboro ma ọ bụ isii nke sochiri nke oke na oke oke nwere mmekọahụ, iji immunofluorescence na microscopy confocal.
Nsonaazụ gosipụtara na MOR na DOR internalization mụbara n'ihi nsị anụ ahụ.
Enwere mmekọrịta n'etiti ego maka mmekorita nwoke na nwanyị na ogo nke itinye akwụkwọ maka MOR, mana ọ bụghị maka DOR. MOR intern malizationba buru ibu n’ime oke oke na -emekarị ugboro ugboro karịa anụmanụ na-agba naanị otu ugboro. Achọtara ihe ntanetị dị mkpa nke DOR naanị na anụmanụ na-emechi emechi otu ugboro. Achọgharịkwara mgbanwe na MOR, DOR na beta njide2, metụtara mmekọ nwoke na nwanyị. A na-atụ aro na copulation satiety nwere ike ịba uru dị ka usoro ihe omumu iji mụọ banyere uru ihe ọmụmụ banyere nnabata dị n'ụwa dị.
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