- Labarin shine labarin wannan binciken: Shirye-shiryen haɓakar ƙwayar ƙwayar maƙasudin lafiya da maƙasudin motsa jiki ta hanyar VTA Dopamine Neuronal Populations
By Tom Corwin, Lahadi, Feb. 20, 2011
Fredrick da Antonio Jackson da Laura Rodriguez sun yi gurnani bayan sun yi tsere-da-tsere a Tsallake Tsallake. Sun yarda cewa suna son ɗan ƙaramin tashin hankali da haɗari - bayan duk, su Marines ne. Antonio, 27, yana son abin nadi.
"Wani lokacin sai ka ji kamar, 'Ba zan iya yarda da kawai na yi haka ba,'" in ji shi. “Da zarar kun sauka daga gare ta, kuna kamar, 'Oh, ya kamata na dawo kan wannan. Yayi kyau. ' ”
Kamar yadda ya bayyana, kwakwalwar wasu mutane na iya jin daɗin ɗan tsoro, kamar yadda bincike daga Jami'ar Kimiyyar Kiwon Lafiya ta Georgia da Cibiyar Kiwon Lafiya ta haiwararrun Shangwararrun Shangwararru ta Shanghai a China. Binciken su, wanda aka buga a makon da ya gabata a cikin jaridar PLoSOne, mayar da hankali kan ƙwayoyin sarrafa kwayoyin halitta a cikin ƙananan kwakwalwa, ko VTA, a kwakwalwa.
"A cikin littafin littafin, VTA cibiyar bayar da lada ce ko kuma tsunduma cikin shaye-shayen miyagun kwayoyi," in ji marubucin marubucin Dokta Joe Z. Tsien, wani darakta a Cibiyar Bincike ta Brain da Halayyar a GHSU. Tunanin farko an yi tunanin duk abin da ta yi don amsawa da ƙarfafa martani ga abubuwa masu kyau.
Tsien ya ce "Abin da takardarmu za ta nuna ba haka batun yake ba."
Masu bincike sunyi aiki tare da ƙwayoyin da aka yi amfani da ƙwayoyin hannu tare da 'yan lantarki don yin rikodin ƙaddamar da kayan aiki na zamani. Daga nan sai aka ba su kyauta mai kyau, kamar karɓar pellet na sukari, da kuma mai da hankali ga haɗari, irin su girgiza akwatin da linzamin kwamfuta ya kasance. Kusan dukkanin kwayoyin samar da kwayoyin halitta a cikin wannan kwakwalwar sun amsa abubuwan da suka faru a cikin tsoro, inji Tsien.
Waɗannan ƙananan ƙwayoyin ƙwayoyin cuta suna ba da amsa "ba kawai ga lada ba amma kuma suna da ƙarfi sosai ga mawuyacin abubuwan da suka faru," in ji shi. Kodayake yawancin murjiyoyin an danne su ko kuma an rufe su saboda tsoro, amma suna da matukar “kwarin gwiwa” a cikin farin ciki bayan taron ya kare, in ji Tsien.
"Waɗannan ƙananan ƙwayoyin na iya ba da wani irin bayani na inji don tursasa halayyar neman sha'awa," in ji shi. "Waɗannan abubuwan da ake tsammani suna da ban tsoro, amma muna iya ganin babban tashin hankali wanda zai haifar da sakin kwayar cutar ta dopamine, wanda hakan na iya bayyana dalilin da ya sa wasu mutane - ba duka mutane ba, wasu mutane ke jin kunya daga gare shi - suna da sha'awar irin wannan haɗarin haɗari . ”
A zahiri, masu binciken sun sami damar gano wani yanki na ƙananan ƙwayoyin cuta, kimanin kashi 25 cikin ɗari a cikin wannan yankin ƙwaƙwalwar, waɗanda ke murnar abubuwan da suka faru, in ji Tsien. Dangane da akidar da ta gabata cewa yankin kwakwalwa ya fi son motsa jiki, wannan abin “mamaki ne kwarai da gaske,” in ji shi.
"Hakan na iya zama wani ɓangare na wannan daidaitawar ko kuma neman halayyar neman ɗoki," in ji shi.
An haɗu da wannan motsa jiki tare da sauti a baya, kuma waɗannan sakonni sun jawo martani, amma sau da yawa ba a lokacin da aka sanya dabba a cikin wani akwatin daban ba, yana nuna cewa martani sun kasance da matukar mahimmanci.
Wannan "na iya taimakawa wajen bayyana dalilin da ya sa mahalli ke taka rawar gani wajen haifar da sha'awa ko ƙarfafa halaye," in ji binciken.
Har ila yau, ya nuna dangantakar dake tsakanin lada da azabtarwa ba haka ba ne da aka yanke-da-dried, inji Tsien.
"Su dangi ne," in ji shi. “Idan kun samu kari a kowace rana, to bayan wani lokaci ba kwa jin wannan wata lada ce saboda ana sa ran hakan. Ta wani bangaren kuma, idan a kowace rana ka samu hukunci kuma wata rana ba ka samu ba, ka ji wannan sakamako ne. Shi ya sa nake ganin wannan zai taimaka mana mu fahimci dalilin da ya sa kwakwalwarmu ke ci gaba da samun wannan dabarar da za ta iya daidaita bayanai masu yawa, ”masu kyau da marasa kyau.
Ga Rodriguez, ya bayyana dalilin da ya sa ta ci gaba da kallon fina-finai mai ban tsoro da racing.
"Kuna son sake dawowa," in ji ta. “Kana son komawa baya ka hau abin birgewa. Kuna samun ɗan tsayi daga ciki. Yana jin daɗi. ”
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