Farashin J Neurosci. 2017 Afrilu 26. doi: 10.1111/ejn.13586.
van Steenbergen H 1,2 , Watson P 3,4 , Wiers RW 3,5 , Hommel B 1,2 , de Wit S 3,4.
Abstract
Nazarin MRI na yau da kullun na ci gaba da fahimtar hanyoyin da ke tattare da corticostriatal wanda ke kan gaba wanda aka sa gaba a kai-a kai, neman abinci na yau da kullun. A karshen wannan, mun yi amfani da tsarin kwalliyar Pavlovian-kayan aiki (PIT). A lokacin gwajin, mahalarta suna da 'yanci don yin amsoshin kayan aikin da aka koya (maɓallan maɓallin hagu da dama) don sakamakon popcorn da Smarties. Mahimmanci, kafin wannan gwajin rabin mahalarta an zaunar da su akan popcorn ɗayan kuma akan Smarties - wanda ya haifar da rage sha'awar waɗannan sakamakon. Bugu da ƙari, yayin gwargwadon gwajin gwajin, an gabatar da alamun Pavlovian masu alaƙa da abinci a bango.
A cikin layi tare da karatun da suka gabata, mun gano cewa mahalarta sun sami damar yin niyya ta hanyar da aka bi don cimma buri yayin rashin halayen Pavlovian, ma'ana cewa takamaiman satiation wanda aka zaɓi yana mai da martani ga abincin. Koyaya, gabatar da kwaskwarimar Pavlovian ta nuna son kai ga kyautar abincin da aka danganta ba tare da yin la’akari da sati ba. Binciken MRI na aikin ya bayyana cewa, a cikin rashin alamun lambobin Pavlovian, kashin baya na tsinkaye na farko yana da ƙimar sakamako. Sabanin haka, a lokacin gwaji da aka yi, ma'anar BOLD a cikin ɗabi'ar gaba mai banbanci ya bambanta tsakanin amsoshin da suka dace da kuma jituwa da sakamako mai alaƙa da alama. Bugu da ƙari, mun gano wani yanki a cikin ventral amygdala wanda ke nuna ingantaccen aikin haɗin gwiwa tare da masu zuwa a lokacin gwaji na cued. Binciken MRI na fasalin ya ba da tabbataccen shaida don shigar da tashoshin corticostriatal: bayanan watsa labarai da aka watsa game da bayanai sun bayyana cewa haɗuwa da takaddun ƙwayar farin-ƙwayar ƙwayar ƙwayar cuta zuwa ga ventromedial prefrontal cortex annabta amsawa don har yanzu sakamako mai mahimmanci; kuma tabbataccen abu mai launin toka a cikin cortex premotor ya yi hasashen tasirin cuwaɗan Pavlovian.
KALMOMI MAI MUHIMMANCI: Da'irori na Corticostriatal; Yanke shawara; Hoton Tensor na Yaɗawa; Hoton Magnetic Resonance Mai Aiki; Halayyar da aka tsara don cimma buri; Halayyar al'ada; Canja wurin Kayan Aiki na Pavlovian; Tsarin Halittar Voxel
PMID: 28444823
DOI: 10.1111/ejn.13586