COV LUS QHIA: Qhov kev tshawb fawb Korean tshawb fMRI no siv lwm cov kev tshawb fawb hauv lub hlwb rau cov neeg siv porn. Zoo li Cambridge University cov kev tshawb fawb nws pom cue vim raug lub hlwb ua kom cov qauv ntawm cov poj niam uas yog tus neeg uas yog cov qauv ntawm cov neeg quav yeeb quav tshuaj. Nyob rau hauv txoj kab nrog ntau German kev tshawb fawb nws pom alterations nyob rau hauv prefrontal cortex uas phim cov kev cai pom nyob rau hauv yeeb tshuaj addicts.
Thaum nws ua ntau yam ntawm lwm cov kev tshawb fawb, phau ntawv Kauslim no kuj ntxiv cov hauv qab no:
- Nws kuaj xyuas lub hlwb ntxiv rau hauv cov teeb meem cue-vim raug mob, thiab nrhiav tau tag nrho cov lus teb nrog ntau dua siv dua nyob hauv kev tswj ntawm kev noj qab haus huv. Lwm lub paj hlwb regions: thalamus, sab laug caudate nucleus, txoj cai supramarginal gyrus, thiab txoj cai dorsal anterior cingulate gyrus.
- Yog dab tsi tshiab yog qhov kev tshawb pom zoo kawg nkaus ua ntej ntawm prefrontal cortex cov qauv pom nyob rau hauv cov neeg quav: Cov loj dua cue-reactivity rau kev sib deev duab, tsis tau inhibited teb rau lwm yam kev loj hlob. Nyob rau hauv ib qho quav, cues ntsig txog kev quav ua rau muaj qhov twv ua ntej lub cortex tua cov khoom plig muaj txiaj ntsig nrog "mus tau nws" cov cim. Nws kuj tseem ua rau tsis tshua muaj siab nyob hauv kev teb rau cov khoom plig txhua hnub. Ntawd yog, tsawg kev rau siab nrhiav kev coj ua khoom plig.
Pem hauv ntej. Behav. Neurosci., 30 kaum ib hlis 2015
LINK TO TAG NRHO COV KEV KAWM NTAWV
Ji-Woo Seok thiab Jin-Hun Sohn*
- Department of Psychology, Hlwb Lub Tsev Kawm Ntawv Lub Cev Kev Tshawb Fawb, Chungnam National University, Daejeon, Sab Qab Teb Kauslim Teb
Cov kev tshawb fawb txog cov yam ntxwv ntawm cov tib neeg uas muaj qhov tsis haum lub siab tau nce zuj zus vim yog muaj kev txhawj xeeb ntau ntxiv txog qhov teeb meem hypersexual cwj pwm (PHB). Tam sim no, tus me ntsis tau paub txog lub hauv paus kev coj tus cwj pwm thiab neural mechanisms ntawm kev sib deev muaj siab. Peb txoj kev tshawb nrhiav tsom xyuas neural cuam tshuam txog kev muaj siab rau kev sib deev nrog kev tshwm sim cuam tshuam txog kev ua haujlwm sib nqus resonance imaging (fMRI). Nees nkaum-peb tus neeg muaj PHB thiab 22 hnub nyoog muaj txiaj ntsig zoo noj qab haus huv tswj tau raug kuaj thaum lawv pom qhov kev sib deev thiab tsis nyiam kev nyiam kev nyiam. Cov ntsiab lus 'theem ntawm qhov kev ntshaw kev sib deev raug txheeb xyuas hauv kev teb rau txhua qhov kev xav ntawm kev sib deev. Txheeb ze ntawm kev tswj hwm, cov tib neeg muaj PHB tau paub ntau dua thiab ua kom muaj kev sib deev muaj zog thaum sib deev los ntawm qhov kev xav deev. Cov kev ua haujlwm loj dua tau pom nyob hauv caudate nucleus, qis qis parietal lobe, dorsal anterior cingulate gyrus, thalamus, thiab dorsolateral prefrontal cortex hauv PHB pawg tshaj li pawg tswj hwm. Ntxiv rau, cov qauv hemodynamic hauv cov chaw ua kom sib txawv ntawm cov pab pawg. Ua raws li cov kev tshawb pom ntawm lub hlwb tshawb nrhiav kev quav tshuaj yeeb dej caw thiab kev coj tus cwj pwm, cov tib neeg muaj tus cwj pwm coj ntawm PHB thiab kev muaj lub siab xav nthuav tawm kev ua kom muaj kev cuam tshuam hauv prefrontal cortex thiab thaj chaw subcortical. Hauv kev xaus, peb qhov txiaj ntsig yuav pab txhawb tus cwj pwm coj tus cwj pwm thiab cuam tshuam cov neural mechanism ntawm cov tib neeg muaj PHB.
Introduction
Qhov teeb meem ntawm hypersexual (PHB) txhais tias yog kev koom tes nrog kev sib deev rov qab ua nrog tsis muaj kev txwv ntau ntawm kev sib daj sib deev thiab kev coj tus cwj pwm txawm tias muaj kev paub txog cov txiaj ntsim kev tsis zoo (Goodman, 1993; Carnes, 2001, 2013). Cov neeg uas raug kev txom nyem los ntawm PHB tuaj yeem ntsib teeb meem hauv lawv tsev neeg cov kev sib raug zoo thiab kev ua haujlwm. Tsis tas li ntawd, lawv yuav muaj feem ntau dua rau kev cog lus kev kis kab mob kev sib deev los yog muaj kev sib deev tsis tau los ntawm kev sib deev kev sib deev (Schneider thiab Schneider, 1991; Kuzma thiab Dub, 2008). Hauv Teb Chaws Meskas, 3-6% ntawm cov tub ntxhais kawm hauv zej zos thiab cov tsev kawm qib siab muaj PHB (Coleman, 1992; Dub, 2000; Seegers, 2003). Hauv Kaus Lim, kwv yees li 2% ntawm tag nrho cov tub ntxhais kawm ntawv qib siab muaj PHB (Kim thiab Kwak, 2011). Vim nws muaj kev prevalence thiab teeb meem muaj feem, cov kev phom sij ntawm kev sib raug zoo yog pom hauv zej zog vim tias muaj xwm txheej ntawm PHB zoo li yuav loj tuaj.
Txawm hais tias qhov teeb meem ntawm PHB tam sim no yog pom, nws tsis muaj nyob rau hauv DSM-5 (American Psychiatric Association, 2013) Cov kev sib cav tseem tab tom sib tham raws li seb puas siab ntsws hypersexual yuav tsum tau cais ua tus kab mob; Yog li no, tsis muaj kev pom zoo los ntawm nws txoj kev txhais, kev faib tawm, los yog kev tshuaj ntsuam xyuas. Qhov no qhia txog cov teeb meem hauv kev tsim cov qauv kev cais tawm vim tsis muaj lub hom phiaj thiab cov kev tshawb fawb los ntawm cov teeb meem muaj feem xyuam nrog kev tsis sib haum xeeb.
Txawm hais tias, kev faib tawm ntawm PHB yog ib qho teeb meem tseem ceeb, nws tau npaj siab tias ntau yam kev sib deev yuav tsum tau cais ua ib pawg ntawm cov kev ntshawv siab vim tias PHB muaj cov tsos mob uas zoo ib yam li lwm hom kev quav tshuaj (Goodman, 2001; Kor thiab lwm tus, 2013). Qhov kev ntshaw ntawm txoj kev xav zoo yog hais txog cov kev sib raug zoo ntawm cov kab mob kev nyuab siab. Kev tshawb xyuas kev pom tau pom tau hais tias qhov kev ua ntawm lub hlwb hauv thaj tsam uas muaj kev koom tes hauv kev xav yog hloov kho cov neeg muaj yees quav tshuaj (Garavan li al., 2000; Tapert li al., 2003; Franklin li al., 2007;McClernon li al., 2009). Kev coj cwj pwm, kev twv txiaj, internet gaming, thiab tus cwj pwm kev ua plees ua yi, uas tsis koom nrog kev noj tshuaj kuj tseem muaj qhov ntshaw siab uas zoo nkaus li muaj feem xyuam rau kev hloov kho hauv cov cheeb tsam hauv lub hlwb (Crockford li al., 2005; Ko et al., 2009;Kühn thiab Gallinat, 2014; Voon li al., 2014).
Kev ntsuam xyuas lub hlwb kev xav ntawm kev quav yeeb quav tshuaj thiab kev coj tus cwj pwm coj tau pom tias muaj kev hloov hauv qhov prefrontal cortex (PFC) thiab subcortical nqi zog circuits hauv cov ntsiab lus nrog cov kab mob (Goldstein thiab Volkow, 2011). Qee qhov, cov kev tshawb fawb no tau pom hais tias qhov kev koom tes tseem ceeb ntawm PFC hauv kev quav yeeb quav, ob leeg los ntawm nws cov cai ntawm thaj tsam ntawm limbic thiab nws txoj kev koom tes hauv cov kev sib txuam ntawm kev siv tshuaj yeeb dej caw thiab kev coj cwj pwm. Kev cuam tshuam kev ua haujlwm ntawm PFC ua rau muaj kev puas tsuaj hauv kev txhawj xeeb thiab kev ntxub ntxaug, xws li kev ua tsis ncaj ncees rau ntau hom kev xav, xws li hauv kev quav yeeb quav tshuaj thiab kev coj cwj pwm, thiab tsis tshua muaj siab rau kev ua kom muaj txiaj ntsim zoo tshaj (Goldman-Rakic thiab Leung, 2002; Goldstein thiab Volkow, 2011).
Zoo ib yam li cov ntsiab lus ntawm kev tshawb nrhiav txog neuroimaging rau PHBs pom tias cov neeg uas muaj PHBs muaj ntau dua qhov kev sib deev muaj siab nyiam piv txwv ntawm kev noj qab haus huv thiab qhov kev ntshaw uas muaj zog yog txuam nrog ntau hom kev hnov lus neural nyob rau hauv cov lus teb sab qaum teb ntawm dorsal-ventral striatal-amygdala haumxeeb network (Voon li al., 2014). Nyob rau hauv ib lub paj hlwb thiab kev cob qhia kev ua haujlwm, Kühn thiab Gallinat (2014) pom hais tias ntau zaus pornography raug cuam tshuam nrog hloov hlwb lub hlwb thiab ua haujlwm hauv cov cheeb tsam PFC thiab tej zaum yuav ua rau ib tug nyiam mus nrhiav cov ncauj lus tshiab thiab ntau dua kev sib deev.
Cov kev tshawb fawb no tau muab pov thawj tias muaj kev ntshaw thiab muaj kev txawv txav ntawm lub cev muaj txiaj ntsig kuj muaj kev koom tes hauv PHB, txawm tias tus cwj pwm tsis yog qhov tsim teeb meem ntawm kev puas hlwb.
Hmoov tsis, qhov tseeb ntawm cov ntaub ntawv hais txog kev sib deev hauv kev sib deev hauv cov tib neeg nrog PHB tsis txaus. Cov kev tshawb fawb dhau los ntawm lub hlwb cov cuab yeej pib ua kev sib deev hauv cov tib neeg uas muaj PHB tau siv cov pa block paradigms thaum lub cev nqaj hlau resizing magnetic teeb meem (fMRI) thiab ib lub caij ntev raug rau cov stimulation erotic. Hauv kev tshawb fawb txog kev sib deev, qhov kev nthuav qhia pom zoo tseem ceeb ntawm qhov kev taw qhia ntawm kev pom thiab vim muaj kev sib txawv ntawm cov ntaub ntawv ua (Bühler li al., 2008). Hauv kev tsim qauv, qhov ntev ntawm qhov kev nthuav qhia kev mob yog qhov ntev, thiab qhov tshwm sim ntawm kev ua kom tsis tu ncua nyob hauv ib lub block yog qhov paub tseeb kiag li (Zarahn li al., 1997). Vim li no, cov qauv tsim tawm yuav tsim cov cheeb tsam uas muaj kev paub txog kev paub txog, xws li muaj kev tu ncua, kev tswj hwm saum, thiab kev tiv thaiv kev sib deev arousal. Qhov no yuav ua rau txo kev xav ntawm kev nyuaj siab thiab yog li hloov qhov pib qeeb paj hlwb (Schafer li al., 2005). Txaus siab rau, cov kev tsim muaj feem xyuam nrog cov xwm txheej yog qhov tsis zoo rau cov qauv kev pom zoo rau kev kuaj pom lub hlwb, thaum lawv muaj kev tshaj tawm txog kev ua haujlwm hemodynamic (Birn li al., 2002).
Yog li ntawd, lub hom phiaj ntawm txoj kev tshawb no yog los
(1) rov muab cov kev tshawb pom yav dhau los ntawm kev plees kev yeem hauv kev sib deev rau cov neeg uas muaj PHBs,
(2) qhia txog cov kev hloov hauv lub hlwb kev ua haujlwm hauv thaj tsam uas paub txog kev mob siab, thiab
(3) to taub qhov txawv ntawm qhov hemodynamic cov lus teb ntawm cov cheeb tsam ntawm lub hlwb dhau sij hawm rau cov neeg uas muaj PHBs los ntawm kev siv fMRI kev tshwm sim.
Peb pom tias cov tib neeg uas muaj PHBs yuav pom tias muaj kev sib deev ntau dua li cov kev tswj kev noj qab haus huv thiab lub cheeb tsam lub hlwb, xws li PFC thiab cov khoom plig hauv subcortical circuits, qhia kev ua haujlwm thiab cov lus teb hemodynamic.
txoj kev
Cov neeg koom
Kev tshawb nrhiav tam sim no 23 heterosexual txiv neej koom rau hauv pab pawg neeg PHB [muaj hnub nyoog = 26.12, standard deviation (SD) = 4.11 xyoo] thiab 22 heterosexual txiv neej koom rau pawg tswj hwm (mean age = 26.27, SD = 3.39 xyoo). Zaum 70 cov neeg tuaj koom tau raug nrhiav tau los ntawm cov chaw kho mob rau kev coj tus cwj pwm muaj teeb meem nrog kev sib deev thiab kev sib daj sib deev tsis sib thooj. Cov txheej txheem ntawm cov menyuam kawm ntawv tau ua raws li PHB cov kev ntsuas ntawm cov kev tshawb fawb dhau los (Table S1; Carnes li al., 2010; Kafka, 2010). Tnws cais tawm yog cov nram no: hnub nyoog tshaj 45 los yog hauv 18; ib qho kev puas siab puas ntsws xws li kev quav dej caw, kev nyuaj siab, kev nyuaj siab ploj, kev puas siab puas ntsws bipolar, los yog obsessive-compulsive disorder; tam sim no noj tshuaj; keeb kwm kev mob taub hau loj; nyiam txivneej; cov ntaub ntawv txhaum cai; los sis tsis tsim nyog rau duab (piv txwv li, muaj hlau nyob hauv nws lub cev, mob astigmatism, lossis claustrophobia). Cov kws kho mob tau tshawb xyuas cov kev sib tham ntawm tag nrho cov neeg muaj peev xwm, thiab ib pawg kawg ntawm 23 Cov Txiv Neej uas tau ntsib cov txheej txheem ntawm cov menyuam kawm ntawv thiab tsis cais cov kev xaiv raug xaiv rau pawg neeg PHB. Rau pawg tswj hwm, 22 cov neeg tuaj koom nrog cov pej xeem cov pej xeem (hnub nyoog, poj niam txiv neej, theem kev kawm, thiab qib nyiaj) uas sib haum ntawm pawg neeg PHB tau xaiv. Tag nrho cov neeg koom tau muab kev pom zoo kev pom zoo tom qab cov ntsiab lus ntawm qhov kev tshawb fawb tau piav qhia rau lawv. Lub Chungnam National University Institutional Review Board tau pom zoo rau cov kev sim thiab kev tso cai pom zoo (pom zoo zauv: 201309-SB-003-01). Txhua tus neeg tau txais nyiaj raug mob (150 las) rau lawv txoj kev koom tes.
Ntsuas Seev
Cov neeg koom ua tiav cov lus nug uas muaj cov lus nug txog lawv cov pej xeem thiab cov kev ua haujlwm rau kev xev rau cov 6 lub hlis dhau los thiab cov ntawv ntsuas, xws li Barratt Impulsiveness Scale-11 (Patton li al., 1995), Cov lus nug ntawm Buss-Perry Aggression (Buss thiab Perry, 1992), Cov lus nug Beck Depression (Beck li al., 1996), Beck ntxhov siab cov lus nug (Beck li al., 1996), Kev Sib Haum Ua Phev Txhaum Kev Sib Deev-R (SAST-R; Carnes li al., 2010), thiab Hypersexual Behavior Inventory (HBI; Reid li al., 2011; rooj 1). Cov lus nug ntawm kev coj tus cwj pwm kev ua plees ua yi yog hnub nyoog ntawm kev sib deev thawj zaug thiab kev sib daj sib deev tam sim no. Ib qho tshwj xeeb yog kev sib deev tau txhais tias yog kev sib raug zoo uas tsuas yog ob tug neeg koom nrog kev sib daj sib deev nkaus xwb nrog lwm tus. A tsis muaj kev sib deev tau txhais tias kev tswj cov kev sib deev ntau yam nrog ntau tus neeg sib deev sib txawv tsis muaj kev tiv thaiv kev sib raug zoo hauv kev sib raug zoo.
ROOJ 1
Cov lus 1. Piav yam ntxwv.
Cov lus nug hais txog kev sib deev nrog kev sib raug zoo nrog kev sib deev txhua lub limtiam, qhov ntau zaus ntawm kev zoo siab rau txhua lub limtiam, kev saib duab pornography txhua lub limtiam, thiab tag nrho cov neeg koom nrog kev sib deev hauv 6 lub hlis dhau los. Tsis tas li ntawd, qhov SAST-R (Carnes li al., 2010) thiab HBI (Reid li al., 2011) raug siv los ntsuam xyuas cov neeg kawm ntawv PHB ntawm cov neeg koom. Tus SAST-R muaj 20 lus nug tsim los ntsuam xyuas qhov kev sib daj sib deev ntawm kev sib daj sib deev. Tus qhab nia yog ntawm 0 rau 20 cov ntsiab lus, nrog cov qhab nias dua uas qhia tias kev sib daj sib deev loj dua. HBI muaj cov lus nug 19, thiab tus qhab nia ntawm 19 rau 95. Tag nrho cov qhab-nees 53 lossis siab tshaj yog qhia tias muaj teeb meem ntawm hypersexualCov. Kev sib xyaw sab hauv (Cronbach's α coefficient) ntawm SAST-R thiab HBI yog 0.91 thiab 0.96, feem (Carnes li al., 2010; Reid li al., 2011).
Kev Txhim Kho Qhov Kev Ntsuam Xyuas thiab Txoj Kev Ntsuas
Ib tug prestudy tau soj ntsuam rau 130 tus txiv neej uas muaj kev sib deev kev ua haujlwm uas tsis koom nrog hauv kev ua haujlwm fMRI kom thiaj li xaiv cov kev sib deev thiab cov tsis muaj cwj pwm tsis txaus siab rau txoj kev tshawb fMRI (Cov Ntaub Ntawv S1). Qhov muag pom tau muaj 20 cov duab uas tau sau los ntawm International Affective Picture System (6 duab; Lang thiab al., 2008) thiab Internet cov websites (14 duab). Cov kev sib deev kev sib deev tshwm sim ntawm cov duab depicting liab qab poj niam thiab kev sib deev ua si. Tsis tas li ntawd, 20 cov duab uas tsis ntxias kev nyiam muaj kev sib daj sib deev tau raug xaiv los ua qhov tsis hnov mob tsis muaj teebmeem. Lawv tau sib raug zoo nrog txoj kev sib deev rau lawv qib siab zoo. Lub suab paj nruag nonsexual qhia tau zoo heev txog kev ua yeeb yam, xws li kev ua si hauv dej, kev ua koob tsheej ntawm ib tus yeej yeej, thiab caij skiing. Cov stimuli tau xaiv thiaj li paub lub hlwb kev ua ub no uas yog kev sib deev nrog kev sib deev los ntawm kev txiav txim tawm yam ua tau los ntawm kev xav ntawm kev plees kev yi thiab kev siab dav dav.
Rau qhov fMRI experimental paradigm, cov lus qhia luv luv txog cov kev sim tau muab rau 6 s thaum pib ntawm kev sim, uas tau ua raws li kev nthuav qhia ntawm kev sib deev los yog kev ua kom tsis muaj ceem rau 5 s txhua. Txhua qhov kev nkag siab ntawm nruab nrab yog 7-13 s (nruab nrab, 10 s) los pab tus neeg koom nrog rov qab mus rau lawv lub xeev qhov tseem ceeb. Kom cov neeg tuaj koom rau qhov stimuli, lawv tau hais kom nias qhov khawm teb thaum lub phiaj xwm npaj txhij txog rau kwv yees li 500 ms rau tag nrho ntawm 12 lub sij hawm thaum muaj lub caij nyoog. Tag nrho lub sij hawm yuav tsum tau sim rau 8 min thiab 48 s (Xam 1).
DAIM NTAWV 1
Daim duab 1. Qhov kev tshwm sim muaj feem cuam tshuam rau kev sib deev muaj siab.
Tom qab ua tiav qhov kev sim ua fMRI, cov neeg koom ua tib zoo saib tib lub suab paj nruag fMRI, thiab lawv yuav tsum teb cov lus nug hauv qab no rau kev soj ntsuam ntawm kev xav.
Ua ntej, lawv tau hais kom lawv teb tias "tau" los sis "tsis muaj" thaum nug tias seb lawv puas xav tau kev sib daj sib deev thaum lawv pom tau tias txhua hom kev mob nkeeg.
Qhov thib ob, lawv yuav tsum tau ua lawv qhov kev sib deev ntawm tsib lub ntsiab lus Likert xws li 1 (khaus tsawg) rau 5 (feem ntau khaus).
Thib peb, cov neeg koom kev kawm ntawm cov kev ntsuas ntawm qhov muaj nqis thiab arousal rau txhua qhov kev xav tau txiav txim siab raws li xya-point Likert nplai.
Cov kev ntsuam xyuas tau tsim los ntawm ob qhov ntev. Kev pom zoo, uas yog qhov zoo lossis tsis zoo, txij ntawm tsis zoo ntawm 1 kom zoo heev ntawm 7, thiab kev xav ntawm kev xav ntawm lub siab ntawm 1 kom muaj siab / aroused ntawm 7. Thaum kawg, cov neeg koom yuav tsum tau tshaj tawm cov kev xav uas lawv tau ntsib dua li kev sib deev thaum lawv raug rau txhua qhov stimulus.
Image Txaus
Cov duab tshaaj tau ua nrog 3.0 T Philips nqaj hlau magnetic resonance scanner (Philips Healthcare, Zoo, Lub Netherlands). Ib qho nkaus xwb txhaj tshuaj echo-planar kuaj fMRI scanning method [imaging variables: lub sij hawm rov ua dua (TR) = 2,000 ms, ncha lub sij hawm (TE) = 28 ms, hlais tuab = 5 mm uas tsis muaj qhov sib txawv, qhov xaus = 64 × 64, saib (FOV) = 24 × 24 cm, ntxeev kaum = 80 °, thiab nyob rau hauv dav hlau = 3.75 mm] tau siv los nrhiav 35 nruam slices ntawm cov ntshav oxygen qib-nyob (BOLD) cov duab. T1-qhov hnyav anatomical dluab tau txais nrog 3-seem dej ntws los ntawm kev rov ua kom rov qab rov qab (TR = 280, TE = 14 ms, ntxeev siab = 60 °, FOV = 24 × 24 cm, matrix = 256 × 256, thiab hlais tuab = 4 mm).
Cov Tshawb Fawb Tsom Cai
Txhawm rau soj ntsuam cov kev coj cwj pwm thiab kev ua neural uas tau ua raws li kev xav ntawm kev sib daj sib deev, cov duab thiab cov ntaub ntawv puas ntsoog rau peb daim duab uas tau ua rau lwm tus xav txawv, xws li qias neeg, chim siab, lossis tsis paub, tsis yog kev sib deev . Ywj siab t-tsis ntawm cov frequencies thiab kev sib tw ntawm kev sib deev ntawm ob pawg neeg tau siv SPSS 22 (IBM Corporation, Armonk, NY, USA). Lub sij hawm ntawm kev sib deev muaj siab suav hais tias yog cov tub ntxhais uas muaj kev sib deev los ntawm cov kev sib deev hauv 20, thiab qhov kev siv ntawm kev sib deev arousal yog qhov nruab nrab ntawm kev sib deev muaj siab rau 20 erotic duab.
SPM8 (Lub Rooj Tsav Xwm Saib Xyuas Kev Txawj Ntse Zoo Zoo, London, UK) yog siv los tshawb xyuas cov ntaub ntawv fMRI. Hauv cov theem ua ntej, MRI duab tau txais kev ua tiav hauv qhov kev txiav txim hauv qab no: daim ntawv teev cov kev kho kom haum, kev hloov kev ua haujlwm, thiab qhov hloov mus rau qhov Standard template los ntawm Montreal Neurological Institution (MNI). Tom qab, cov normalized dluab twb smoothed nrog ib 8-hli Gaussian ntsiav.
Tom qab ua tiav qhov preprocessing, cov qauv tsim muaj ob qho kev mob (kev sib deev mob thiab qhov tsis muaj xwm txheej) tau tsim rau txhua tus neeg koom los paub lub cheeb tsam uas muaj kev sib deev nrog kev ua si. Qee leej neeg soj ntsuam ntawm kev sib piv ntawm kev sib daj sib deev tsis raug siv rau qhov kev ntsuam xyuas random, thiab txhais tau cov duab tau tsim rau txhua qhov kev kawm. Ib tug qauv t-tsis txog ntawm cov duab raug siv los ntsuam xyuas qhov teebmeem ntawm cov teebmeem hauv txhua pab pawg hauv cov duab sib piv hauv cov kev ntsuam xyuas tus kheej. Ob-qauv t-tsis tau ua kom paub qhov txawv ntawm ob pawg rau lub hlwb cov lus teb hauv kev sib deev ntawm qhov tsis muaj xwm txheej. Tsis tas li ntawd xwb, kev txheeb xyuas kev sib txuas lus tau ua nyob rau hauv pawg neeg PHB los txiav txim siab rau cov cheeb tsam ntawm kev sib raug zoo uas muaj feem xyuam nrog kev siab tawv ntawm kev hypersexuality raws li SAST-R. Vim tias qhov sib txawv ntawm cov lus nug ntawm cov lus nug kuj yuav tsis dhau los qhia tau ntau qhov sib txawv hauv cov pawg tswj hwm, kev sib txheeb ntawm kev sib txheeb tsis tau ua hauv pawg tswj xyuas. P qhov tseem ceeb tshaj 0.05 (Cuav Ntaus Nqi Cwjpwm (Claim Discovery Rate, corrected, qhov loj npaum li cas ≥ 20) lossis 0.001 (tsis meej, pawg loj ≥ 20) yog qhov tseem ceeb rau lub hlwb yam li cov qib no raug lees txais hauv kev tshawb fMRI. Tag nrho cov hauj lwm ntawm cov voxels activated muaj qhia raws li MNI tswj hauv Cov Ntxhuav 3, 4.
Cov teeb meem ntawm kev hloov ntawm qhov feem pua tau muab rho tawm los ntawm Regions of Interest (ROIs) raws li cov txiaj ntsim ntawm cov neeg sib txawv ntawm cov neeg thiab kev txheeb ze sib piv [piv txwv li ob leeg thalamus, txoj cai dorsolateral prefrontal cortex (DLPFC), sab laug caudate nucleus, txoj cai supramarginal gyrus, thiab txoj cai dorsal anterior cingulate gyrus] nrog MarsBaR (http://www.sourceforge.net/projects/marsbar). Cov ROIs tau tsim los ntawm qhov muab 5-mm kheej ib ncig ntawm cov kab ke qhia hauv Cov Ntxhuav 3, 4. Txhawm rau kuaj xyuas cov teeb meem ntawm lub cev ntawm lub cev ntawm lub cev ntawm lub cev, lub sijhawm BOLD teeb lub sij hawm kuj tau muab rho tawm los ntawm ROIs thaum lub sij hawm nthuav tawm ntawm txhua qhov kev sib deev (tag nrho ntawm 12 s; 5 s thiab 7 s tom qab) rau tag nrho cov neeg koom. Lub sij hawm kawm tau tom qab ntawm cov neeg koom hauv txhua pawg.
Raws li kev soj qab taug kev ntawm kev sib raug zoo los laij cov kev sib haum xeeb coefficient, kev sib raug zoo ntawm cov qhab nia ntawm SAST-R thiab HBI thiab feem pua cov teeb meem hloov hauv cov ROIs raws li cov txiaj ntsim ntawm kev txheeb ze sib piv (Cov lus 4) tau soj ntsuam hauv PHB pab pawg nrog SPSS 22.
tau
Cov txiaj ntsim ntawm Kev Ntsuam Xyuas Kev Xav
Ntawm 20 kev tswj hwm kev noj qab nyob zoo, tsuas yog ob leeg qhia lwm tus cwj pwm txawv dua li kev sib deev arousal teb rau peb cov kev sib deev kev sib deev. Ib tug neeg koom rau hauv pawg tswj hwm tau qhia tias ob txoj kev sib deev ntawm cov poj niam sexual stimuli vim raug yuam ua kev chim siab thiab npau taws, thaum lwm tus neeg koom hauv pawg tswj hwm tau hais tias ib daim duab ntawm kev sib deev ua rau luag. Peb qho duab ntawm kev sib daj sib deev uas ntxias kev xav ntawm lwm yam kev sib deev arousal raug tshem tawm ntawm cov ntaub ntawv ntsuam.
Kev ywj pheej t-tsis qhia tias tsis muaj kev sib txawv ntawm cov neeg hauv kev loj hlob thiab kev coj noj coj ua teb rau kev sib deev cues [kev muaj muag: t(43) = 0.14, p> 0.05, Cohen's d = 0.042; arousal: t(43) = 0.30,p> 0.05, Cohen's d = 0.089]. Tsis tas li ntawd, qhov feem pua ntawm kev sib deev ntawm cov tub ntxhais hluas ntawm 20 erotic duab uas evoked muaj siab kev sib deev showed tias pawg neeg PHB muaj kev sib deev muaj siab ntau dua li cov pab tswj thaum muaj kev sib deev nrog kev sib deevkuv [t(43) = 3.23, p <0.01, Cohen's d = 0.960]. Tnws khov kho ntawm kev sib deev arousal pom tias pawg neeg PHB tau ntsib ntau dua kev sib deev sib deev tshaj qhov kev pab pawg hauv kev teb rau kev sib deev rau cov duab [t(43) = 14.3, p <0.001, Cohen's d = 4.26]. Cov txiaj ntsim ntawm kev soj ntsuam ntawm kev puas siab puas ntsws yog tshwm nyob rau hauv Table 2.
ROOJ 2
Cov lus 2. Kev soj ntsuam txog kev puas hlwb.
fMRI cov ntsiab lus
Nyob rau hauv PHB, kev ua kom raug pom nyob hauv ob sab / nruab nrab ntawm frontal gyri [Brodmann thaj tsam (BA) 9], cuneus / precuneus (BA 7, 18, thiab 19), qaug zog, thalamus, thiab cingulate gyri (BA 24 thiab 32 ) teb rau kev sib deev stimuli piv nrog cov stimulus nonsexual. I(pawg Xwm Txheej), kev tiv thaiv tau tshwm sim nyob rau hauv ob sab nrab / inferior frontal gyri (BA 9), cuneus / precuneus (BA 7, 18, thiab 19), striatum, thalamus, thiab sab laug cingulate gyrus (BA 24) Tus nqi,p <0.05).
Hauv qhov kev soj ntsuam ntawm pawg neeg, PHB pawg tau pom ntau dua kev ua rau hauv txoj cai dorsal anterior cingulate cortex (dACC; BA 24 thiab 32), bilateral thalami, sab laug caudate nucleus, txoj cai DLPFC (BA 9, 46), thiab txoj cai supramarginal gyrus (BA 40) ntsig txog kev ua kom nyob rau pawg tswj xyuas thaum lub sij hawm kis tau tus cwj pwm ntawm kev sib deev piv nrog rau kev ua kom tsis muaj zog. Tsis muaj hlwb hauv cheeb tsam hauv pawg tswj xyuas pom kev ua kom ntau dua hauv pawg neeg PHB. Tag nrho cov hauj lwm sib koom ua rau cov voxels qhib ua muaj qhia tau tias MNI tswj hauv Cov Ntxhuav 3, 4. Xam 2 qhia qhov feem pua ntawm cov kev hloov hauv kev tswj thiab PHB pawg hauv txhua qhov kev sim (qhov ntawd, kev sib deev thiab cov tsis muaj cwj pwm) rau cov xaiv ROIs, thiab daim duab 3 qhia txog lub sij hawm ntawm txhua pawg ntawm qhov kev hloov ntawm cov teeb meem ntawm txhua lub sij hawm taw tes rau hauv ROIs thaum nthuav tawm ntawm txhua qhov kev sib deev (tag nrho ntawm 12 s; 5 thiab 7 s tom qab ntawd) raws li cov txiaj ntsim ntawm pawg neeg soj ntsuam.
ROOJ 3
Cov lus 3. Lub hlwb hauv cheeb tsam txheeb xyuas los ntawm pawg neeg soj ntsuam.
Cov lus 4. Hlwb thaj chaw uas tau txheeb xyuas hauv kev txheeb ze rau hauv PHB thaum muaj kev sib deev kev sib deev.
DAIM NTAWV 2
Daim duab 2. Cov qhab-nees ntawm kev sib tw ntawm pawg neeg. (A) Bilateral thalamus (MNI coordinate; x = 6, y = -36, z = 4) (B) Txoj cai dorsolateral prefrontal cortex (MNI coordinate;x = 56, y = 10, z = 22) (C) Sab laug caudate nucleus (MNI coordinate; x = -38, y = -32, z = 2)(D) Txoj cai supramarginal gyrus (MNI coordinate; x = 50, y = -42, z = 32) (E) Txoj cai dorsal anterior cingulate gyrus (MNI coordinate; x = 24, y = -16, z = 34). Cov txiaj ntsim ntawm kev sib piv ntawm kev ua kom nyob rau hauv kev sib deev kev ua haujlwm tsis muaj kev txhawb zog ntawm cov neeg mob PHB thiab kev tswj hwm (p <0.05, Tus Nqi Tshawb Nrhiav Tsog, Kho). Cov pawg tswj hwm thiab PHB pawg yog sawv cev raws li xim xiav thiab xim liab, ua ntu zus. Lub y-axis qhia cov feem pua hloov pauv thiab cov cim yuam kev sawv cev Txheem Tus Qauv Ntawm Qhov Txhais Tau Zoo.
DAIM NTAWV 3
Daim duab 3. Lub sijhawm ntawm cov lus teb hemodynamic hauv txhua cheeb tsam ntawm kev txaus siab.(A) Bilateral thalamus (MNI coordinate; x = 6, y = -36, z = 4) (B) Txoj cai dorsolateral prefrontal cortex (MNI coordinate; x = 56, y = 10, z = 22) (C) Sab laug caudate nucleus (MNI coordinate; x = -38, y = -32, z = 2) (D) Txoj cai supramarginal gyrus (MNI coordinate; x = 50, y = -42, z = 32) (E) Txoj cai dorsal anterior cingulate gyrus (MNI coordinate; x = 24, y = -16, z = 34). Y-axis thiab x-axis qhia txog qhov sib txawv ntawm cov teeb liab thiab lub sijhawm (s), raws li, thiab qhov yuam kev tuav tam ntawm tus Standard Error of Meaning.
Qhov kev sib piv ntawm cov cheeb tsam uas muaj feem xyuam nrog SAST-R score tau qhia tias txoj cai thalamus thiab DLPFC (BA 9) tau sib haum nrog cov qhab-nees xeem S-R (p <0.001, tsis paub meej) nyob rau hauv PHB pawg thaum lub sijhawm kov cov kev sib deev, raws li qhia nyob rau hauv Table 4. Tnws cov kev tshwm sim ntawm kev soj ntsuam tom qab pom tau hais tias feem pua ntawm cov teeb liab hloov uas tau muab rho tawm ntawm txoj cai thalamus thiab DLPFC sib raug zoo nrog qhov sib txawv ntawm hypersexuality, raws li tau hais hauv daim duab 4. Qhov teeb meem feem pua hloov ntawm txoj cai thalamus thiab txoj cai DLPFC sib cuam tshuam nrog SAST-R cov qhab nia ntawm PHB pab pawg thaum lub sij hawm kis tau tus mob ntawm kev sib deev (txoj cai thalamus: r = 0.74, n = 23, p <0.01; txoj cai DLPFC: r = 0.63, n = 23, p <0.01). Ntxiv rau, feem pua teeb liab lub pauv ntawm txoj cai DLPFC thiab txoj cai thalamus tau muaj feem ntsig txog HBI cov qhab nia hauv pawg PHB (txoj cai thalamus: r = 0.65, n = 23, p <0.01; txoj cai DLPFC: r = 0.53, n = 23, p <0.01), raws li pom hauv daim duab 4.
DAIM NTAWV 4
Daim duab 4. Cov qhab-nees ntawm kev txheeb xyuas kev sib raug zoo. Sab laug, muaj zog magnetic resonance imaging (fMRI) correlational tsom. Cov cheeb tsam uas qhia txog kev sib deev ntawm lub hlwb ua si thaum muaj kev sib deev thiab kev sib deev ntawm kev sib deev Screen-R (SAST-R)p <0.001, rov tsis pom kev). Txoj cai, kev sib raug zoo nruab nrab ntawm cov feem pua teeb liab tawm tau muab rho tawm los ntawm txhua thaj chaw thiab cov qhab nia kev sib deev [piv txwv li, SAST-R thiab Hypersexual Cwj Pwm Kev Coj Tus Kheej (HBI) cov qhab nia]. Txoj kab xoo qhia txog qhov kev sib daj sib deev, thiab y-axis sawv cev rau qhov feem pua hloov pauv. (A) Bilateral thalamus (MNI coordinate; x = 4, y = -32, z = 6) (B) Txoj cai dorsolateral prefrontal cortex (MNI coordinate; x = 56, y = 8, z = 22).
kev sib tham
Txoj kev tshawb xyuas tam sim no xyuas seb puas muaj qhov sib txawv hauv cov qib kev sib deev ntawm cov neeg uas muaj mob PHB thiab kev tswj kev noj qab haus huv thiab, yog tias muaj, puas qhov txawv no yog muaj feem xyuam rau kev hloov kho hauv cov neural substrates kev sib deev hauv cov tib neeg no. Raws li tau hais tseg, PHB pawg tau pom tias muaj kev sib daj sib deev ntau npaum li cas ntawm kev sib deev thiab hloov kho rau hauv PFC thiab subcortical chaw piv rau cov tswj. Cov kev tshwm sim no tau pom tias cov kev hloov hauv cov kev sib hloov hauv cov hlab ntsha neural uas ua rau lub siab xav ua rau tus cwj pwm muaj kev sib deev zoo ib yam li cov neeg teb rau qhov kev nthuav qhia rau cov neeg uas muaj kev quav yeeb quav tshuaj lossis kev coj tus cwj pwm (Garavan li al., 2000; Tapert li al., 2003; Crockford li al., 2005; Franklin li al., 2007;Ko et al., 2009; McClernon li al., 2009). Voon li al. (2014) qhia txawv txav txawv txav thiab kev hloov ntawm thaj chaw hauv thaj chaw uas muaj kev ntshaw siab rau cov tib neeg uas muaj kev sib deev ntawm kev sib deev. Peb replicated thiab ncua cov ntsiab lus los ntawm kev soj ntsuam cov sij hawm series ntawm kev ua kom lub sij hawm tag nrho 12 s hauv cov cheeb tsam uas muaj kev sib deev muaj siab.
Raws li kev tshawb nrhiav, kev soj ntsuam ntawm cov kev soj ntsuam ntawm kev puas siab puas ntsws pom tias pawg neeg PHB pom ntau dua kev sib deev muaj siab tshaj qhov kev tswj hwm thaum muaj kev sib deev kev sib deev, uas pom tias pawg neeg no muaj tsawg dua rau kev sib deev. Thaum muaj kev sib deev muaj siab, cov pab pawg neeg hu ua PHB pom tias muaj kev sib deev ntau dua li cov pab pawg neeg tau ua. Qhov no tshwm sim tau zoo ib yam li cov kev tshawb pom yav dhau los rau cov tib neeg uas muaj kev koom tes ntawm PHB (Laier li al., 2013; Laier thiab Hom, 2014; Voon li al., 2014), qhov tshwj xeeb tshaj yog qhia tias qhov kev ntshaw ntawm kev saib duab liab qab yuav ua rau lub luag haujlwm tseem ceeb hauv cybersex kev tiv thaiv.
Cov kev tshwm sim ntawm lub hlwb cov lus teb rau kev sib deev nrog kev sib deev nrog cov kev tshawb pom yav dhau los uas tau pom hais tias kev ua si yog pom hauv hlwb thaj chaw koom nrog rau kev sib deev xav lossis kev txhawb zog / kev cia siab, nrog rau kev sib deev lossis kev sib txeeb / kev txav siab, thaum txhua tus koom raug kev deev stimuli (Georgiadis thiab Kringelbach, 2012). Cov txiaj ntsim ntawm cov kev sib piv ntawm lub hlwb tuaj qhia txog kev ua kom zoo hauv DLPFC (BA 9) thiab subcortical regions, nrog rau txoj cai dACC (BA 24 thiab 32), sab laug caudate nucleus, txoj cai supramarginal gyrus (BA 40), thiab muaj cai thalamus, thiab cov kev hloov no tej zaum yuav cuam tshuam nrog tus yam ntxwv coj cwj pwm ntawm PHB pawg. Txuas ntxiv rau lub hlwb ua kom zoo, peb tau kuaj xyuas ib lub sij hawm series ntawm cov lus teb hemodynamic hauv cov cheeb tsam no thiab tom qab lub caij uas muaj siab rau kev sib deev hauv cov cheeb tsam no.
Ntawm cov cheeb tsam no, sab laug caudate nucleus thiab txoj cai ACC (BA 24 thiab 32) thiab txoj cai DLPFC yog xav tias yuav tsum tau txuam nrog kev txhawb zog ntawm kev sib deev muaj siab. Kev koom tes ntawm cov caudate nucleus hauv kev xav thiab kev sib yuav ua nqi yuav suav rau nws cov lus teb rau kev sib deev kev sib deev (Delgado, 2007). Tus dorsal striatum yog qhib lub sijhawm thaum muaj nqi zog (Delgado, 2007), uas muaj peev xwm qhia txog qhov xav tau uas yog txuam nrog kev cia siab. Nyob rau hauv kev tshawb ntawm neural cov lus teb txuam nrog kev siv cov duab liab qab, kev ua kom ntau dhau ua rau pornography raug tej zaum yuav ua rau hnav thiab downregulation ntawm striatum, nrog rau cov caudate nucleus, nyob rau hauv cov tswj kev noj qab haus huv (Kühn thiab Gallinat, 2014). Txawm li cas los xij, hauv txoj kev tshawb nrhiav tam sim no, kev ua kom ntau tus tau pom nyob rau hauv caudate nucleus hauv PHB pab pawg, txawm tias pawg neeg PHB saib pornography ntau dua. Cov kev sib txawv ntawm qhov kev tshwm sim ntawm qhov kev kawm tam sim no thiab cov ntawm Kühn thiab Gallinat (2014) tej zaum yuav piav qhia los ntawm qhov txawv ntawm cov neeg koom. Qhov ntawd yog, qhov sib txawv ntawm kev siv cov txiv neej noj qab nyob zoo hauv txoj kev tshawb xyuas yav dhau los, peb txoj kev tshawb nrhiav tau rau cov neeg uas muaj PHB. Cov khoom pov thawj pom tau hais tias qhov caudate nucleus yog qhov tseem ceeb rau txoj kev coj tus cwj pwm thiab kev kho tus cwj pwm (Vanderschuren thiab Everitt, 2005). Qhov qhib rua ntawm caudate nucleus nyob rau hauv txoj kev tshawb no yuav qhia tau tias kev sib deev cue-reactivity yog tsim los tom qab rov dhau kev sib deev kev.
Lub DACC paub tias yog muaj feem xyuam rau cov kev xav ntawm kev sib deev (Redouté li al., 2000; Arnow li al., 2002; Hamann li al., 2004; Ferretti li al., 2005; Ponseti li al., 2006; Paul et al., 2008). Peb cov kev tshawb pom ntawm DACC ua kom pom tias nws muaj lub luag haujlwm nyob hauv kev sib deev, thiab cov txiaj ntsim tau zoo li cov kev kawm txog kev xav txog neural ua si hauv cov ntsiab lus nrog kev sib deev compulsive behaviors (Voon li al., 2014). Tsis tas li ntawd, lub DACC paub tias tseem ceeb hauv kev pib ua tus cwj pwm coj ntawm lub hom phiaj los ntawm kev daws teeb meem ntawm qhov kev tawm tsam rau kev coj cwj pwm thiab kev tiv thaiv ntawm kev sib tw (Devinsky li al., 1995; Arnow li al., 2002;Karama li al., 2002; Moulier li al., 2006; Safron li al., 2007). Neuroanatomically, cov haujlwm DACC rau DLPFC thiab parietal lobe (Devinsky li al., 1995; Pizzagalli li al., 2001). Nyob rau hauv txoj kev tshawb no, qhov qhib rau hauv DACC hauv PHB pawg yuav muaj kev cuam tshuam nrog kev sib cav sib ceg ntawm kev sib deev ua rau kev ua yeeb yam thiab kev ua kom muaj kev cuam tshuam cov kev cuam tshuam ntawm cov teeb meem ntawm qhov teeb meem thaum lub sijhawm qhia txog kev sib deev.
Qhov qhib rua ntawm supramarginal gyrus yog txuam nrog ntau lub xim rau cov hom phiaj uas tau pom tias yog kev sib deev cues (Redouté li al., 2000; Stoléru li al., 2012). Cov kev tshawb fawb yav dhau los tau npaj siab tias kev ua kom muaj zog rau kev sib deev yog ib qho tseem ceeb hauv kev tswj xyuas kev sib deev (Barlow, 1986; Janssen thiab Everaerd, 1993) thiab muaj feem xyuam rau txoj kev xav ntawm kev sib deev (Kagerer li al., 2014). Hauv kev tshawb nrhiav tam sim no, kev ua kom tau supramarginal yuav muaj kev cuam tshuam cov xim ntau dua los ntawm PHB rau kev sib deev thiab cov uas yuav ua rau ntau theem ntawm kev sib deev sib piv nrog rau pawg tswj hwm.
Ntawm cov cheeb tsam uas tau ua rau cov kev sib tw ua ke, DLPFC thiab thalamus ncaj nraim nrog qhov kev sib daj sib deev ntawm kev sib daj sib deev nyob rau hauv PHB cov ntsiab lus. Peb pom tias kev ua kom ntau dua thalamus, uas yog nyob rau hauv kab nrog tshawb pom dhau los ntawm cov kev tshawb fawb ntawm kev sib deev arousal (Redouté li al., 2000; Moulier li al., 2006). Raws li cov kev tshawb fawb dhau los ntawm kev sib deev muaj siab, qhov ua kom thalamus muaj feem xyuam rau cov lus teb ua muaj sia (piv txwv tias, kev npaj rau kev sib daj sib deev) uas yog vim raug yuam los ntawm kev sib deev thiab muaj kev sib haum xeeb nrog cov pob txha (MacLean thiab Ploog, 1962; Redouté li al., 2000; Moulier li al., 2006). Interestingly, peb kuj pom ib lub dav dua thiab dav dav hemodynamic hauv lub thalamus piv nrog rau hauv cov tswj. Qhov kev sib cav thiab qhov dav no tseem ceeb qhia tau tias kev sib deev arousal yog muaj zog thiab ntev mus rau cov neeg uas muaj PHB.
Zoo ib yam li cov kev tshawb nrhiav ntawm neural ua si rau cov tib neeg uas muaj kev tiv thaiv thaum muaj kev tu siab, peb pom hloov PFC cov kev ua haujlwm nyob rau hauv pab pawg neeg PHB. Lub PFC plays lub luag haujlwm tseem ceeb hauv kev npaj yav tom ntej thiab kev ua haujlwm (Bonson li al., 2002). Neuroanatomically, PFC txuas nrog rau ntau qhov chaw, nrog rau DACC, caudate nucleus, thiab parietal lobe (Devinsky li al., 1995; Pizzagalli li al., 2001; Goldman-Rakic thiab Leung, 2002). Cov kev tshawb fawb yav dhau los txog kev quav yeeb tshuaj tau qhia tias kev ua haujlwm ntawm lub network no, nrog rau PFC, cuam tshuam nrog PFC cov cai ntawm limbic cov nqi zog thaj tsam thiab nws cov kev koom tes hauv kev ua haujlwm siab dua, nrog rau kev tswj tus kheej, kev ua kom zoo nkauj, thiab paub txog (Goldman-Rakic thiab Leung, 2002; Feil li al., 2010; Goldstein thiab Volkow, 2011; Kühn thiab Gallinat, 2014). Qee qhov, cov kev tshawb fawb no tau pom tias DLPFC cuam tshuam txog kev ua tsis ncaj ncees, ua rau cov tsos mob tshwm sim, xws li kev txawv txav tsis zoo rau ib hom kev ua yeeb yam xws li hauv kev quav yeeb quav tshuaj thiab kev coj tus cwj pwm tsis zoo thiab tsis txaus siab rau lub cev (Goldman-Rakic thiab Leung, 2002; Goldstein thiab Volkow, 2011). Hauv txoj kev tshawb xyuas tam sim no, kev soj ntsuam ntau dua DLPFC ua rau pawg neeg PHB piv rau pawg tswj hwm yuav muaj kev cuam tshuam ntev heev rau kev sib deev cues.
Hauv cov ntsiab lus, PHB pawg pom tias muaj kev sib deev ntau dua uas yog txuam nrog kho hlwb. Cov kev tshawb pom no qhia tias pawg neeg PHB yuav txhawj xeeb rau kev sib deev ntau dua thiab tias nws muaj peev xwm teb tau yooj yim vim hais tias cov lus teb rau kev sib deev tsis pub muaj kev sib haum xeeb zoo. Cov kev txwv ntawm txoj kev kawm tam sim no yog raws li nram no. Ua ntej, qhov kev sib tw ntawm cov ntsiab lus yog Neeg Esxias. Thib ob, txoj kev tshawb no cuam tshuam txog cov poj niam txiv neej nkaus xwb, thiab yav tom ntej cov kev tshawb fawb nrog poj niam txiv neej thiab tub nyiam txiv neej yuav tsum pab kom nkag siab zoo dua. Cov ntaub ntawv PHB nrog cov kab mob tshwm sim ntawm kev puas siab puas ntsws tsis koom rau hauv qhov kev tshawb fawb, yog li ua kom txoj kev tshawb xyuas ntawm neural ua haujlwm raws li hauv PHB. Txawm li cas los, raws li kev tshawb nrhiav los ntawm Weiss (2004), 28% ntawm cov txiv neej nrog kev mob nkeeg ntawm kev mob nkeeg ntawm qhov kev nyuaj siab loj. Kev siv cov teeb meem no ua ke tsis pub muaj kev paub txog cov kev tshawb fawb los ntawm cov pejxeem thoob ntiajteb. Thaum kawg, ob pab pawg neeg muaj peev xwm sib txawv nrog rau kev paub txog tus kheej thiab / lossis kev xav ntawm lub siab vim kev kho mob ntawm cov neeg koom tes hauv PHB. Peb tau sim txo cov kev sib txawv ntawm cov tswj thiab PHB cov kev sib txuas los ntawm kev sib txawv rau qhov tseem ceeb ntawm cov neeg mob, nrog rau lub hnub nyoog, kev kawm ntawv, thiab kev ua haujlwm, rau kev sib piv thiab siv cov txheej txheem nruj nruj, xws li muaj cov kev puas siab puas ntsws thiab kev siv tam sim no psychotropic tshuaj, rau ob pawg. Tom ntej no, peb npaj yuav tshuaj xyuas cov kev hloov ntawm lub sijhawm kho mob lossis kev kho mob rau cov lus teb, nrog rau cov lus teb rau kev sib deev, ntawm cov neeg uas muaj PHB.
Dua li ntawm cov kev txwv no, cov ntsiab lus ntawm qhov kev tshawb fawb no tuaj yeem pab txhawb rau cov ntawv nyeem thiab muaj qhov cuam tshuam rau yav tom ntej ntawm kev tshawb fawb. Peb txheeb xyuas lub hlwb tshwj xeeb uas tau muaj kev sib deev nrog kev sib deev thiab kev hloov ntawm lub cev ntawm cov cheeb tsam ntawm cov cheeb tsam ntawm cov kev kawm nrog PHB. Zoo li lub hlwb kev tshawb xyuas txog kev quav yeeb quav tshuaj thiab kev coj cwj pwm, PHB yog muaj feem xyuam nrog cov kev hloov pauv hauv PFC thiab subcortical, txawm tias tsis muaj neurotoxicity ntawm cov tshuaj. Peb cov qhabnias yog li ntawd tseem ceeb rau kev coj tus cwj pwm thiab kev sib raug zoo ntawm cov tib neeg nrog PHB, thiab tawm ib kauj ruam dhau qhov piav qhia ntawm cov yam ntxwv xws li cov kev tshawb fawb dhau los.
Nyiaj
Cov haujlwm no tau txais kev pabcuam los ntawm Kauslim Tebchaws Lub Koomhaum Kev Ncaj Ncees (Tsis yog E35600) thiab kev tshawb nrhiav nyiaj ntawm 2014 Chungnam National University.
Teebmeem ntawm Cov Lus Qhia Txaus
Cov sau phau ntawv tshaj tawm tias qhov kev tshawb fawb tau ua thaum tsis muaj kev lag luam los yog nyiaj txiag kev sib raug zoo uas yuav raug txwv tsis pub muaj kev cuam tshuam ntawm kev txaus siab.
ACKNOWLEDGMENTS
Cov sau phau ntawv xav ua tsaug rau Kauslim Teb Kws Teev Kauslim rau kev tso cai rau txoj kev tshawb fawb ntawm lub Department of Human Imaging Center los ntawm kev siv 3T MRI scanner (Phillips).
Cov Ntaub Ntawv Ntxiv
Cov ntaub ntawv ntxiv rau daim ntawv no muaj nyob hauv online ntawm: http://journal.frontiersin.org/article/10.3389/fnbeh.2015.00321
References
American Psychiatric Association (2013). Diagnostic thiab Ntawv Qhia Tawm Ntawm Cov Kev Xiam Hlwb Xiam Hlwb, 5th Edn. Arlington, VA: American Mental Publishing Publishing.
Arnow, BA, Desmond, JE, Banner, LL, Glover, GH, Solomon, A., Polan, ML, li al. (2002). Hlwb pob txha thiab kev sib deev arousal hauv kev noj qab haus huv, cov menyuam muaj hnub nyoog. Lub hlwb 125, 1014-1023. doi: 10.1093 / brain / awf108
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Barlow, DH (1986). Ua rau kev sib deev tsis meej: lub luag haujlwm ntawm kev ntxhov siab thiab kev cuam tshuam kev cuam tshuam. J. Nrog koj tham. Clin. Psychol. 54, 140-148. doi: 10.1037 / 0022-006X.54.2.140
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Beck, AT, Steer, RA, thiab Brown, GK (1996). Beck Depression Inventory-II. San Antonio, TX: Psychological Corporation.
Birn, RM, Cox, RW, thiab Bandettini, PA (2002). Nrhiav kom paub txog kev kwv yees nyob rau hauv kev tshwm sim muaj feem xyuam fMRI: xaiv txoj kev pom kev zoo tshaj plaws. Neuroimage 15, 252-264. doi: 10.1006 / nimg.2001.0964
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Dub, DW (2000). Epidemiology thiab phenomenology ntawm tus cwj pwm kev sib deev compulsive. CNS Spectr. 5, 26-72. doi: 10.1017 / S1092852900012645
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Bonson, KR, Grant, SJ, Contoreggi, CS, Txuas, JM, Metcalfe, J., Weyl, HL, li al. (2002). Neural systems thiab cue-vim raug yuam ua yeeb yaj kiab. Neuropsychopharmacology 26, 376–386. doi: 10.1016/S0893-133X(01)00371-2
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Bühler, M., Vollstädt-Klein, S., Klemen, J., thiab Smolka, MN (2008). Puas erotic stimulus kev nthuav qhia kev tsim rau lub hlwb kev ua qauv? Kev tshwm sim-sib txuas thiab blocked fMRI designs. Behav. Lub hlwb Funct. 4:30. doi: 10.1186/1744-9081-4-30
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Buss, AH, thiab Perry, M. (1992). Cov lus nug txog kev ua phem. J. Pers. Soc. Psychol. 63, 452-459. doi: 10.1037 / 0022-3514.63.3.452
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Carnes, P. (2013). Contrary to Hlub: Pab Tus Neeg Mob Kev Sib Deev. Center City, MN: Hazelden Publishing.
Carnes, P., Green, B., thiab Carnes, S. (2010). Tib yam tseem txawv: rov ntsuam xyuas kev sib deev ntawm kev sib deev (SAW) kom muaj kev ywj pheej thiab poj niam txiv neej. Pw ua ke. Khwv yees. Compuls. 17, 7-30. doi: 10.1080 / 10720161003604087
Carnes, PJ (2001). Tawm ntawm Ntxoov ntxoo: Nkag siab Kev Tiv Thaiv Kev Sib Deev. Center City, MN: Hazelden Publishing.
Coleman, E. (1992). Puas yog koj tus neeg mob mob ntawm kev coj tus cwj pwm ntawm kev sib deev? Psychiatr. Ann. 22, 320–325. doi: 10.3928/0048-5713-19920601-09
Crockford, DN, Goodyear, B., Edwards, J., Quickfall, J., thiab el-Guebaly, N. (2005). Cue-vim raug lub hlwb ua si ntawm cov neeg twvtxiaj. Biol. Psychiatry 58, 787-795. doi: 10.1016 / j.biopsych.2005.04.037
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Delgado, MR (2007). Kev Tshaj Tawm Txog Kev Tshaj Tawm los ntawm cov tib neeg hauv plab. Ann. NY Acad. Sci. 1104, 70-88. doi: 10.1196 / annals.1390.002
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Devinsky, O., Morrell, MJ, thiab Vogt, BA (1995). Kev koom tes ntawm anterior cingulate cortex rau tus cwj pwm. Lub hlwb 118, 279-306. doi: 10.1093 / lub hlwb / 118.1.279
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Feil, J., Sheppard, D., Fitzgerald, PB, Yücel, M., Lubman, DI, thiab Bradshaw, JL (2010). Txhaj, nrhav kev tshawb nrhiav, thiab lub luag haujlwm ntawm cov kev coj ua ntej hauv kev tswj hauv kev tswj cov kev txwv tswj. Neurosci. Biobehav. Rev. 35, 248-275. doi: 10.1016 / j.neubiorev.2010.03.001
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Ferretti, A., Caulo, M., Del Gratta, C., Di Matteo, R., Merla, A., Montorsi, F., et al. (2005). Dynamics ntawm cov txiv neej kev sib deev arousal: cov Cheebtsam ntawm lub hlwb ua haujlwm qhia los ntawm fMRI. Neuroimage 26, 1086-1096. doi: 10.1016 / j.neuroimage.2005.03.025
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Franklin, TR, Wang, Z., Wang, J., Sciortino, N., Harper, D., Li, Y., li al. (2007). Limbic qhib rau kev haus luam yeeb cues uas tsis zoo rau kev tshem tawm nicotine: ib qho kev tshawb fMRI txoj kev tshawb fawb. Neuropsychopharmacology 32, 2301-2309. doi: 10.1038 / sj.npp.1301371
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Garavan, H., Pankiewicz, J., Bloom, A., Cho, JK, Sperry, L., Ross, TJ, li al. (2000). Cue-vim raug yuam ua yeeb yaj kiab: neuroanatomical qhov tshwj xeeb rau cov neeg siv yeeb tshuaj thiab kev siv yeeb tshuaj. Kuv. J. Psychiatry 157, 1789-1798. doi: 10.1176 / appi.ajp.157.11.1789
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Georgiadis, JR, thiab Kringelbach, ML (2012). Tib neeg kev sib deev qhov kev sib deev: lub hlwb muaj peev xwm saib xyuas kev sib deev nrog lwm yam kev lom zem. Kev kawm. Neurobiol. 98, 49-81. doi: 10.1016 / j.pneurobio.2012.05.004
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Goldman-Rakic, PS, thiab Leung, HC (2002). "Functional architecture ntawm dorsolateral prefrontal cortex nyob rau hauv liab thiab tib neeg," nyob rau hauv Ntsiab cai ntawm Front Lobe Function, eds DT Stuss thiab RT Knight (New York, NY: Oxford University Press), 85-95.
Goldstein, RZ, thiab Volkow, ND (2011). Tsis zoo ntawm cov prefrontal cortex hauv kev quav tshuaj: kev tshawb nrhiav txog neuroimaging thiab kev kuaj mob. Nws. Rev. Neurosci. 12, 652-669. doi: 10.1038 / nrn3119
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Goodman, A. (1993). Kev kuaj mob thiab kev kho mob ntawm kev sib daj sib deev. J. Kev Sib Haum Sawv Cev Marital Ther. 19, 225-251. doi: 10.1080 / 00926239308404908
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Goodman, A. (2001). Dab tsi yog nyob rau hauv ib lub npe? Terminology los tsim ib qho mob ntawm tus cwj pwm sib deev. Kev Nyuaj Siab Ntxiv. Compuls. 8, 191-213. doi: 10.1080 / 107201601753459919
Hamann, S., Herman, RA, Nolan, CL, thiab Wallen, K. (2004). Txiv neej thiab cov poj niam sib txawv hauv amygdala qhov kev xav kom pom kev sib deev. Nws. Neurosci. 7, 411-416. doi: 10.1038 / nn1208
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Janssen, E., thiab Everaerd, W. (1993). Txiav txim siab ntawm cov txiv neej kev sib deev arousal. Ann. Rev. Kev sib deev Res. 4, 211-245. doi: 10.1080 / 10532528.1993.10559888
Kafka, MP (2010). Hypersexual teeb meem: kev thov mob rau DSM-V. Koov. Pw ua ke. Behav. 39, 377–400. doi: 10.1007/s10508-009-9574-7
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Kagerer, S., Wehrum, S., Klucken, T., Walter, B., Vaitl, D., thiab Stark, R. (2014). Kev sib deev ntawm kev sib deev: tshawb xyuas cov tib neeg sib txawv hauv kev xav tsis zoo rau kev sib deev. PLOS IB 9: e107795. doi: 10.1371 / journal.pone.0107795
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Karama, S., Lecours, AR, Leroux, JM, Bourgouin, P., Beaudoin, G., Joubert, S., thiab al. (2002). Cov cheeb tsam ntawm lub hlwb ua rau cov txiv neej thiab pojniam thaum lub sij hawm saib ntawm cov zaj duab xis erotic excerpts. Hum. Hlwb Mapp, 16, 1-13. doi: 10.1002 / hbm.10014
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Kim, M., thiab Kwak, JB (2011). Cov tub ntxhais hluas cybersex qhov yees hauv cov xov xwm digital yog era. J. Tib neeg. 29, 283-326.
Ko, CH, Liu, GC, Hsiao, S., Yen, JY, Yang, MJ, Lin, WC, li al. (2009). Lub hlwb kev ua si nrog kev ua si ntawm kev ua si hauv online gaming. J. Psychiatr. Res. 43, 739-747. doi: 10.1016 / j.jpsychires.2008.09.012
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Kor, A., Fogel, Y., Reid, RC, thiab Potenza, MN (2013). Puas tsim nyog tias hypersexual tsis meej tau muab cais ua kev tiv thaiv? Pw ua ke. Khwv yees. Compuls. 20, 27-47. doi: 10.1080 / 10720162.2013.768132
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Kühn, S., thiab Gallinat, J. (2014). Hlwb pob txha thiab kev sib txuas ua haujlwm nrog cov duab liab qab siv: lub hlwb ntawm porn. JAMA Psychiatry 71, 827-834. doi: 10.1001 / jamapsychiatry.2014.93
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Kuzma, JM, thiab Dub, DW (2008). Epidemiology, kev nthuav dav, thiab keeb kwm ntawm kev coj tus cwj pwm kev sib deev compulsive.Psychiatr. Clin. North Am. 31, 603-611. doi: 10.1016 / j.psc.2008.06.005
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Laier, C., thiab Hom, M. (2014). Empirical cov pov thawj thiab theoretical xav txog ntawm yam tseem ceeb los ntawm cybersex yees ntawm lub tswv yim-cwj pwm saib. Pw ua ke. Khwv yees. Compuls. 21, 305-321. doi: 10.1080 / 10720162.2014.970722
Laier, C., Pawlikowski, M., Pekal, J., Schulte, FP, thiab Hom, M. (2013). Cybersex kev tiv thaiv: kev ua plees ua yaus muaj kev sib deev thaum saib duab liab qab thiab tsis sib txuas lus ntawm kev sib deev ua qhov txawv. J. Behav. Khwv yees. 2, 100-107. doi: 10.1556 / JBA.2.2013.002
Lang, PJ, Bradley, MM, thiab Cuthbert, BN (2008). Thoob Ntiaj Teb Cov Yees Duab Daim Qauv (IAPS): Kev Tshaj Xo Ntawm Cov Duab thiab Cov Kev Qhia Siv. Cov Ntaub Ntawv Xov Xwm A-8. Gainesville, FL: University of Florida.
MacLean, PD, thiab Ploog, DW (1962). Kab mob sawv cev ntawm cerebral erection. J. Neurophysiol. 25, 29-55.
McClernon, FJ, Kozink, RV, Lutz, AM, thiab Rose, JE (2009). 24-h haus luam yeeb tsis pub muaj zog ua haujlwm fMRI-BOLD ua rau kev haus luam yeeb cs hauv cerebral cortex thiab dorsal striatum. Psychopharmacology 204, 25–35. doi: 10.1007/s00213-008-1436-9
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Moulier, V., Mouras, H., Pélégrini-Issac, M., Glutron, D., Rouxel, R., Grandjean, B., et al. (2006). Neuroanatomical correlates ntawm rab qaum erection evoked ntawm photographic stimuli nyob rau hauv tib neeg cov txiv neej. Neuroimage 33, 689-699. doi: 10.1016 / j.neuroimage.2006.06.037
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Patton, JH, Stanford, MS, thiab Barratt, ES (1995). Qhov teeb meem ntawm Barratt Impulsiveness nplai. J. Clin. Psychol. 51, 768-774.
Paul, T., Schiffer, B., Zwarg, T., Krüger, TH, Karama, S., Schedlowski, M., et al. (2008). Lub hlwb lub hlwb kom pom kev sib deev hauv kev sib deev nyob rau hauv heterosexual thiab homosexual caug. Hum. Hlwb Mapp. 29, 726-735. doi: 10.1002 / hbm.20435
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Pizzagalli, D., Pascual-Marqui, RD, Nitschke, JB, Oakes, TR, Larson, CL, Abercrombie, HC, li al. (2001). Cov kev ua ub no ua ntej yuav ua ib yam dab tsi uas yuav tsum tau ua kom paub txog cov kev kho mob ntawm kev nyuaj siab tshaj plaws: kev pov thawj los ntawm lub hlwb hluav taws xob tomography. Kuv. J. Psychiatry 158, 405-415. doi: 10.1176 / appi.ajp.158.3.405
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Ponseti, J., Bosinski, HA, Wolff, S., Peller, M., Jansen, O., Mehdorn, HM, al. (2006). Ib qho kev haumxeeb endophenotype rau kev plees kev yi rau tib neeg. Neuroimage 33, 825-833. doi: 10.1016 / j.neuroimage.2006.08.002
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Redouté, J., Stoléru, S., Grégoire, MC, Costes, N., Cinotti, L., Lavenne, F., et al. (2000). Lub hlwb ua haujlwm ntawm kev ua kom pom kev sib deev hauv tib neeg cov txiv neej. Hum. Hlwb Mapp. 11, 162–177. doi: 10.1002/1097-0193(200011)11:3<162::AID-HBM30>3.0.CO;2-A
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Reid, RC, Garos, S., thiab Carpenter, BN (2011). Kev ntseeg, kev siv tau, thiab kev tsim kho kev xav ntawm Hypersexual Behavior Inventory nyob rau hauv kev soj ntsuam ntawm cov txiv neej. Pw ua ke. Khwv yees. Compuls. 18, 30-51. doi: 10.1080 / 10720162.2011.555709
Safron, A., Barch, B., Bailey, JM, Gitelman, DR, Parrish, TB, thiab Reber, PJ (2007). Neural correlates ntawm kev sib deev arousal nyob rau hauv homosexual thiab heterosexual cov txiv neej. Behav. Neurosci. 121, 237-248. doi: 10.1037 / 0735-7044.121.2.237
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Schafer, A., Schienle, A., thiab Vaitl, D. (2005). Stimulus hom thiab tsim feem hauv cov lus teb hemodynamic rau kev pom kev qias thiab ntshai ntshai. Int. J. Psychophysiol. 57, 53-59. doi: 10.1016 / j.ijpsycho.2005.01.011
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Schneider, JP, thiab Schneider, B. (1991). Kev sib deev, Lies, thiab kev zam txim: Khub niam txiv hais tawm ntawm kev kho kom zoo ntawm kev sib deev.Center City, MN: Hazeldon Publishing.
Seegers, JA (2003). Cov tsos mob ntawm kev sib deev nyob rau hauv tsev kawm ntawv qib siab. Pw ua ke. Khwv yees. Compuls. 10, 247-258. doi: 10.1080 / 713775413
Stoléru, S., Fonteille, V., Cornélis, C., Joyal, C., thiab Moulier, V. (2012). Cov kev tshawb fawb txog kev sib deev ntawm kev ua plees ua yig thiab orgasm hauv cov poj niam thiab cov poj niam uas muaj kev noj qab haus huv: kev ntsuam xyuas thiab kev ntsuas. Neurosci. Biobehav. Rev. 36, 1481-1509. doi: 10.1016 / j.neubiorev.2012.03.006
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Tapert, SF, Cheung, EH, Brown, GG, Frank, LR, Paulus, MP, Schweinsburg, AD, li al. (2003). Neural teb rau cov cawv cawv hauv cov hluas thaum haus cawv. Koov. Gen. Psychiatry 60, 727-735. doi: 10.1001 / archpsyc.60.7.727
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Vanderschuren, LJ, thiab Everitt, BJ (2005). Kev coj cwj pwm zoo thiab hlwb nees ntawm kev siv tshuaj yaj yeeb ntawm compulsive. Eur. J. Pharmacol. 526, 77-88. doi: 10.1016 / j.ejphar.2005.09.037
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Voon, V., Mole, TB, Banca, P., Porter, L., Morris, L., Mitchell, S., et al. (2014). Neural correlates ntawm cue reactivity rau cov neeg uas muaj thiab tsis muaj compulsive kev coj cwj pwm. PLOS IB 9: e102419. doi: 10.1371 / journal.pone.0102419
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Weiss, D. (2004). Qhov kev nyuab siab ntawm kev nyuaj siab nyob rau hauv poj niam txiv neej yog tus neeg nyob hauv Tebchaws Meskas. Pw ua ke. Khwv yees. Compulsivity 11, 57-69. doi: 10.1080 / 10720160490458247
Zarahn, E., Aguirre, G., thiab D'Esposito, M. (1997). Kev sim-siv-sim kev sim rau fMRI. Neuroimage 6, 122-138. doi: 10.1006 / nimg.1997.0279
PubMed Abstract | CrossRef Cov Ntaub Ntawv Tag Nrho | Google Scholar
Cov ntsiab lus: teeb meem hypersexual teeb meem, kev sib deev muaj siab, muaj peev xwm ua tau zoo tshaj cov duab tshav, dorsolateral prefrontal cortex, hemodynamic teb
Citation: Seok JW and Sohn JH (2015) Kev Ntsuas Ntawm Lub Neej Kev Sib deev hauv Cov Tib Neeg Muaj Teeb Meem Hypersexual Cwj Pwm.Pem hauv ntej. Behav. Neurosci. 9: 321. doi: 10.3389 / fnbeh.2015.00321
Txais: 18 Lub Rau Hli 2015; Txais: 10 Kaum Ib Hlis 2015;
Luam tawm: 30 Kaum Ib Hlis 2015.
Edited by:
Morten L. Kringelbach, University of Oxford, UK thiab University of Aarhus, Denmark, UK
Rov los:
Matthias Hom, University Duisburg-Essen, lub teb chaws Yelemees
Janniko Georgiadis, University Medical Center Groningen, Netherlands
Copyright © 2015 Seok thiab Sohn. Nov yog tsab xov xwm qhib kev nkag tau faib nyob rau hauv nqe lus ntawm Creative Commons Attribution Licence (CC BY). Kev siv, faib los yog muab luam tawm hauv lwm lub rooj sab laj raug tso cai, yog tias tus thawj tus kws sau ntawv lossis tus muab ntawv pov thawj raug xa tawm thiab tias daim ntawv tshaj tawm thawj zaug hauv phau ntawv no yog raug teev lus, raws li kev lees paub kev kawm. Tsis pub siv, faib lossis muab luam tawm uas tsis ua raws li cov ntsiab lus no.
* Txoj Haujlwm: Jin-Hun Sohn, [email tiv thaiv]
;