- Qhov no yog tsab xov xwm hais txog txoj kev tshawb fawb no: Ua Yuam Ua Txheej ntawm Cov Kev Pom Zoo thiab Kev Nyuaj Hloov Zoo Los ntawm VTA Dopamine Neuronal Coob
Los ntawm Tom Corwin, Sunday, Feb. 20, 2011
Fredrick thiab Antonio Jackson thiab Laura Rodriguez grinned tom qab sib tw mus-karts ntawm Kev Tawm Tsam Hla. Lawv lees tias lawv nyiam me ntsis kev txaus siab thiab txaus ntshai - tom qab tag nrho, lawv tau Marines. Antonio, 27, nyiam nyiam cov ntug dej hiav txwv.
Nws tau hais tias, "Qee lub sijhawm koj txoj kev xav zoo li, 'Kuv ntseeg tsis tau kuv tsuas yog ua qhov ntawd xwb," “Thaum koj tawm mus, koj zoo li, 'Au, kuv tau rov qab los ntawm qhov no. Nws yog qhov zoo. ' ”
Raws li nws hloov tawm, qee tus neeg lub hlwb yuav txaus siab me ntsis kev ntshai, raws li kev tshawb fawb los ntawm Georgia Health Sciences University thiab Shanghai Lub Chaw Haujlwm ntawm Lub Hlwb Piav Qoj Qib Genomics hauv Suav. Lawv cov kev tshawb fawb, luam tawm lub lim tiam dhau los ntawm phau ntawv journal PLoSOne, npaj rau dopamine-producing neurons hauv cheeb tsam ventral tegmental, los yog VTA, hauv lub hlwb.
Dr. Joe Z. Tsien, tus co-tus ntawm lub hlwb thiab kev coj cwj pwm ntawm Discovery Institute ntawm GHSU. Yav dhau los nws tau xav tias txhua yam nws tau ua yog teb thiab txhawb kev teb rau qhov zoo.
Tsien hais tias "Dab tsi peb daim ntawv yuav qhia tias qhov no tsis yog qhov teeb meem no."
Cov kws tshawb fawb tau ua haujlwm nrog cov nas uas nws lub hlwb tau wired nrog electrodes mus rau sau cov sij hawm tua neeg ntawm cov neurons. Lawv tau raug khoov zoo, xws li txais cov pellet suab thaj, thiab kev ntshai ua rau lub siab, xws li tuav lub npov nas. Ze li ntawm tag nrho cov dopamine uas ua rau cov neurons hauv thaj tsam ntawm lub hlwb tau teb rau cov xwm txheej ntshai, Tsien hais.
Cov neurons zoo li "tsis yog rau tus nqi zog xwb, tab sis kuj heev, heev robustly rau cov yeej tseem ceeb tsis zoo," nws hais. Txawm hais tias feem ntau ntawm cov neurons tau raug tsim txom lossis kaw hauv kev teb rau kev ntshai, lawv muaj qhov "rov qab" qhov kev txaus siab tom qab qhov xwm txheej tas, Tsien hais.
"Cov neurons no yuav qhia qee yam ntawm kev piav qhia txog kev tsav tus cwj pwm kom zoo," nws hais. "Cov no yog cov xwm txheej ntshai, tab sis peb tuaj yeem pom qhov muaj kev txaus siab ntau heev uas yuav tsum ua rau tso tawm ntawm dopamine, uas tuaj yeem piav qhia vim li cas qee tus neeg - tsis yog txhua tus neeg, qee cov neeg txaj muag rau nws - muaj kev nyiam los ntawm tus cwj pwm pheej hmoo heev . ”
Qhov tseeb, cov kws tshawb nrhiav tau nrhiav thaj chaw ib leeg ntawm neurons, kwv yees li 25 feem pua hauv thaj tsam ntawd lub hlwb, uas tau zoo siab heev los ntawm cov xwm txheej ntshai, Tsien hais. Hais txog qhov ua dogma dhau los hais tias thaj tsam ntawm lub hlwb nyiam qhov txiaj ntsig stimuli, uas yog "txaus ntshai heev," nws hais.
Nws tau hais tias "Qhov ntawd tuaj yeem yog ib feem ntawm qhov kev hloov kho ntawd lossis kev ua kom zoo siab rau kev coj cwj pwm," nws hais.
Cov stimulus feem ntau ua ke nrog ib lub suab ua ntej, thiab cov kev taw qhia kuj tau ua kom muaj lus teb, tab sis feem ntau tsis yog thaum tus tsiaj raug muab tso rau hauv ib lub thawv txawv, uas qhia cov lus teb tau muaj xwm txheej.
Txoj kev kawm no tau sau tseg tias "cov kev kawm ib puag ncig tau ua lub luag haujlwm tseem ceeb hauv kev ua tus neeg ua txhaum los yog coj tus cwj pwm zoo li cas,"
Nws tseem qhia tau hais tias kev sib raug zoo ntawm kev muab nqi zog thiab kev rau txim yog tsis li txiav-thiab-qhuav, Tsien hais.
Nws hais tias, "Lawv yog kwv tij." “Yog koj tau txais nyiaj txhua hnub, tomqab ib pliag koj tsis xav tias qhov nqi zog no yog vim tias qhov xav tau. Ntawm qhov tod tes, yog tias txhua txhua hnub koj tau txais kev rau txim thiab ib hnub koj tsis tau txais nws, koj xav tias qhov ntawd yog nqi zog. Yog vim li cas kuv xav tias qhov no yuav pab peb to taub vim li cas peb lub hlwb tseem muaj cov txheej txheem hloov kho tau no muaj peev xwm kam nrog cov ncauj lus dav dav, "ob qho tib si zoo thiab tsis zoo.
Rau Rodriguez, nws piav txog vim li cas nws ua rau saib scary movies thiab sib xeem khiav.
Nws hais tias, "Koj xav rov qab pib." "Koj xav khiav rov qab thiab mus tau rau daim coaster roller. Koj tau txais siab me me ntawm nws. Nws zoo. ”
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