BMC Psychiatry. 2018 Dec 20;18(1):396. doi: 10.1186/s12888-018-1974-6.
Chaw ua si J1, Sung JY2, Kim DK2, Kong ID3, Hughes TL4, Kim N5.
Abstract
KEV THOV:
Tus nab npawb ntawm cov neeg uas muaj kev ua si hauv Internet (IGA) yog nce thoob ntiaj teb. IGA paub tias yuav muaj feem nrog tus kheej yam ntxwv, tus cwj pwm tsis zoo, thiab kev mob ntawm lub cev. Txawm li cas los, ob peb cov kev tshawb fawb tau soj ntsuam cov caj ces yam uas muaj feem rau IGA. Qhov kev tshawb nrhiav no yog los soj ntsuam cov koom haum ntawm IGA thiab cov kabmob ntawm kev ntxhov siab txog kev ntxhov siab.
KEV HLOOV:
Qhov kev tshawb fawb no tau tshawb nrog 230 txiv neej kawm tiav qib high school nyob hauv nroog South Kauslim. Peb tau xaiv tsib yam kev sib tw nrog cov neeg sib tw: DAT1, DRD4, NET8, CHRNA4, thiab CRHR1. DAT1 thiab DRD4 cov noob tau genotyped los ntawm polymerase chain reaction, thiab cov NET8, CHRNA4, thiab CRHR1 genes genotyped by pyrosequencing tsom. Peb tau ua qhov kev ntsuam xyuas Chi-square los kuaj xyuas kev sib raug zoo ntawm cov tsib tus neeg sib tw mus rau IGA.
COV LUS QHIA:
Muaj cov AA genotype thiab A allele ntawm tus CRHR1 noob (rs28364027) tau txuam nrog ntau dua qhov sib txawv ntawm pawg IGA pab pawg (p =. 016 thiab p =. 021, feem ntau) rau cov pab pawg tsis yog IGA. Ntawm qhov sib piv, DAT1, DRD4, NET8, thiab CHRNA4 noob polymorphisms tsis pom qhov txawv ntawm pawg IGA thiab pawg tswj hwm.
TXHEEJ XWM:
Cov kev tshwm sim no qhia tias polymorphism ntawm tus CRHR1 noob tau ua lub luag haujlwm tseem ceeb hauv IGA qhov kev tsim txom hauv cov tub ntxhais hluas ntxhais Kauslim teb. Cov kev tshawb pom no muab kev pom zoo thiab lub hauv paus rau kev tshawb nrhiav txog caj ces yam muaj feem xyuam nrog IGA.
KEYWORDS: CRHR1; Gene polymorphism; Kev ua si hauv Internet gaming
PMID: 30572854
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