J Psychiatr Res. 2014 Jul 16. pii: S0022-3956 (14) 00204-0. doi: 10.1016 / j.jpsychires.2014.07.007.
Han DH1, Lee YS1, Shi X2, Renshaw PF3.
Abstract
Cov kev tshawb fawb qhia txog lub hlwb tsis ntev los no qhia tias ob qho tib si rau sab xub ntiag thiab sab nqaij daim tawv yog qhov chaw sib tw tseem ceeb rau kev sib kho cov tsos mob ntawm kev quav yeeb quav tshuaj hauv internet. Peb suav tias qhov tsis xws ntawm kev ua haujlwm ua ntej thiab lub cev nqaij daim tawv ua haujlwm hauv cov neeg mob nrog kev tiv thaiv kev ua si hauv online (PGA) yuav tau xav txog qib N-acetyl aspartate (NAA) thiab cytosolic, choline muaj cov sib xyaw (Cho). Xya Caum peb cov tub ntxhais hluas PGA thiab 38 hnub nyoog thiab cov txiv neej sib luag hauv kev tswj hwm kev noj qab haus huv tau raug xaiv hauv txoj kev tshawb no. Txheej Txheem MR thiab 1H MRS cov ntaub ntawv tau los siv tshuab 3.0 T MRI scanner. Voxels tau raug muab tso rau ntawm sab xis ntawm sab xub ntiag cortex thiab sab hnub qub Hauv txoj cai frontal cortex, qib ntawm NAA hauv PGA tau tsawg dua li cov neeg hauv kev tswj hwm zoo. Hauv lub nruab nrab ib nrab cortex, qib ntawm Cho hauv PGA cov neeg koom nrog qis dua qhov tau pom nyob hauv kev tswj hwm kev noj qab haus huv. Cov Hluas Hluav Taws Xob hauv Is Taws Nem Kev Txom Nyem (YIAS) cov qhab nia thiab cov lus teb thev naus laus zis hauv PGA tau cuam tshuam tsis zoo nrog qeb ntawm NAA nyob rau sab xis pem hauv ntej cortex. Beck Depressive Inventory (BDI) cov qhab nia hauv PGA pawg neeg sib koom ua ke tau cuam tshuam nrog Cho qib nyob hauv qib sab xis. Qhov zoo tshaj plaws ntawm peb txoj kev paub, qhov no yog thawj zaug MRS kawm txog cov tib neeg uas muaj kev sib xyaw "on-line game". Txawm hais tias, cov ncauj lus nrog kev quav tshuaj yeeb yaj kiab "on-line game" hauv kev tshawb fawb tam sim no yog pub dawb los ntawm kev sib koom siab sib deev, cov neeg mob "on-line game addiction" tshwm sim qhia cov yam ntxwv nrog ADHD thiab MDD hais txog kev hloov pauv neurochemical nyob rau hauv sab hauv thiab sab nqaij daim tawv cortices.
KEYWORDS:
Choline cov khoom xyaw; Lub Nruab Nrab Cortex; Medial cortex hauv nruab nrab; N-acetyl aspartate
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