Tasi le onosaʻi mai le fa ma faʻatoa maua mai erectile faʻaletonu le aoga o se tama talavou-taufaʻafefe ata mai le masani falemaʻi faʻataʻitaʻi (2013)

Faʻamatalaga: O suʻesuʻega Italia fou e maua ai le 25% o tagata fou na maua ogaoga O le faʻaaogaina o le erectile i lalo ole 40.

O FAAIUGA: O lenei suʻesuʻega suʻesuʻe na faʻaalia ai o se tasi i tagata e fa o loʻo sailia muamua fesoasoani faafomaʻi mo fou fou ED sa laʻititi nai lo 40 tausaga. Pe tusa ma le afa o alii talavou na mafatia i le ED ogaoga, ma fua tutusa i tagata matutua matutua. I le aotelega, o alii talavou e ese mai i latou matutua matutua e tusa ai ma tulaga o mataupu faafomaʻi ma sosaiete o le sociodemographic.


J Sex Med. 2013 Jul;10(7):1833-41. Pule: 10.1111 / jsm.12179.

Capogrosso P, Colicchia M, Ventimiglia E, Castagna G, Clementi MC, Suardi N, Castiglione F, Briganti A, Cantiello F, Damiano R, Montorsi F, Salone A.

puna

Matagaluega o Urology, University Vita-Salute San Raffaele, Milan, Italia.

lē faʻatino

FOLASAGA:

O le vailaʻau Erectile (ED) o se faitioga masani i tagata i luga o le 40 tausaga, ma o le aofaʻi o fua faʻatatau i le taimi o le matua. O le faʻaauau ma tulaga lamatia o ED i le va o alii talavou ua maeʻa ona suʻesuʻeina.

AIM:

Iloiloina o le sociodemographic ma faʻataʻitaʻiga o alii talavou (faʻamalamalamaina o le ≤ 40 tausaga) saili muamua fesoasoani faafomaʻi mo le fou fou ED pei o la latou masaniga feusuaiga muamua.

METHODS:

Ua maeʻa ona suʻeina faʻamatalaga faʻasalalauga ma faʻamatalaga mai le 439 mulimuli. O faʻamalositino maloloina na maua i le Charlson Comorbidity Index (CCI). Na faʻamaunuuina e tagata maʻi le Faʻamaumauga Faʻavaomalo o Erectile Function (IIEF).

IA FAIA MEA TAIMI:

Faʻamaumauga faʻamaumauga na suʻesuʻeina le eseesega ole sosaiete ma falemai i le va o tagata mamaʻi ≤ 40 tausaga ma> 40 tausaga.

TULAFONO:

O le fou o le ED e pei o le uluai maʻi na maua i 114 (26%) alii ≤ 40 tausaga (uiga [tausaga masani] [SD]]: 32.4 [6.0]; laina: 17-40 tausaga). Tagata mamaʻi ≤ 40 tausaga na i ai le tau maualalo o tulaga faʻaletonu (CCI = 0 i le 90.4% vs. 58.3%; χ (2), 39.12; P <0.001), o le maualalo maualalo tino tino aofaʻi faʻasino aofaʻi (P = 0.005), ma le maualuga maualuga faʻasalalauina aofaʻi testosterone tulaga (P = 0.005) pe a faʻatusatusa i na> 40 tausaga. O talavou ED e masani lava ona faʻaalia le masani o le ulaula tapaa ma faʻaaogaina fualaʻau faʻasaina, pe a faʻatusatusa i tama matutua (uma P ≤ 0.02). O le taimi muamua ejaculation na sili atu ona afaina i tama talavou, ae o le Peyronie faamaʻi na taatele i le vaega matutua (uma P = 0.03).  IIEF, ogaoga le tau o le ED na maua i le 48.8% aliʻi talavou ma le 40% matutua aliʻi (P> 0.05). E faʻapena foi, fua faatatau o le agamalu, agamalu-i-feololo, ma feololo ED e leʻi eseesega tele i le va o vaega e lua.

FAAIUGA:

O lenei suʻesuʻega suʻesuʻe na faʻaalia ai o se tasi i tagata e fa o loʻo sailia muamua fesoasoani faafomaʻi mo fou fou ED sa laʻititi nai lo 40 tausaga. Asili atu le afa o alii talavou sa mafatia i le ED ogaoga, ma fua tutusa i tagata matutua matutua. I le aotelega, o alii talavou e ese mai i latou matutua matutua e tusa ai ma tulaga o mataupu faafomaʻi ma sosaiete o le sociodemographic.

© 2013 International Society for Sexual Medicine.

FUAFUAGA:

Tausaga, Tausiga o Fomaʻi, Faʻatonuga, Matua, Erectile Faʻasalaga, Tulaga o le Soifua Maloloina, Faʻamaumauga Faʻavaomalo o le Erectile Function, Faʻamatalaga Faʻatau, Tamaitiiti

PMID: 23651423


faʻatomuaga

O le vailaʻau Erectile (ED) o se faitioga masani i tagata i luga ole 40 tausaga le matua, ma o le aofaʻi o fua faʻatatau i luga o le tausaga matua [1].
O le tele lava o tusitusiga i luga o le mataupu a ED e masani lava ona tatala i se faʻamatalaga, tusa lava po o le a le amanaia o soʻo se faitau aofai poʻo se ituaiga,
o soʻo se sosaiete faasaienisi o le suʻesuʻega / o le tagata suʻesuʻe e patino, ma o soʻo se tusi faʻasaienisi lea na faʻasalalau ai tusitusiga. I nisi faaupuga, o le matutua o tagata, o le tele foi lea o latou amata feutagaʻi ma ED [2].

I se faʻatusatusaga, ED ua faasolosolo ona maua se taua matafaioi o se faʻata o le soifua maloloina o tamaloloa, manatu taua tele talafeagai i le fatu fatu
laufanua [3-6]. O le mea lea, e mautinoa lava o ED ua oʻo i se taua taua tele e le gata i le matata o vailaʻau, ae e oʻo foʻi i le matata o le soifua maloloina lautele, ona o lona aʻafiaga i vaega lautele o le olaga o le tagata. O le faʻateleina o le fiafia i lenei mataupu na mafua ai le atinaʻeina o le toʻatele
suʻesuʻega e uiga i le aʻafia ma le aʻafia o aʻafiaga a le ED i vaega eseese o tagata gasegase [7, 8]; i lenei tulaga, o le tele o faʻamatalaga ua lolomiina e faasino i le faitau aofaʻi matua ma le matutua, ma sili atu ona patino i tamaloloa i luga o le 40 tausaga o le matua [7-9]. O le mea moni, o tagata matutua, aemaise lava le matutua, e masani ona mafatia mai tulaga leaga-e pei o le maʻisuka, oona, cardiovascular diseases (CVD), ma le maualalo o faailoga urinary symptoms (LUTS) -o nei mea uma ua afaina ai tulaga lamatia mo ED [7-12].

I le isi itu, o le tulaga masani ma tulaga lamatia o le ED i alii talavou na matuā suʻesuʻeina. O faʻamatalaga i luga o lenei vaega o tane na faʻaalia fua o le ED i le va o 2% ma toetoe lava 40% i tamaiti laiti nai lo 40 tausaga [13-16]. I le aotelega, o faʻamatalaga faʻasalalau na faamamafaina ai le taua o le ED i alii talavou, e ui lava o lenei vaega patino o tagata taitoatasi e foliga mai e le tutusa le tutusa o tulaga lamatia o le soifua maloloina o alii matutua oe faitioina le faaleagaina o le erectile [15, 16], ma mafua ai ona talitonu o se vaega o le mafaufau e sili atu ona taatele i tagata gasegase o loʻo i ai le le mautonu o le faʻatuina poʻo le faʻanoanoa o galuega e le faʻaleagaina [17].

I le aotelega, toetoe o suʻesuʻega uma o loʻo lipotia ai le faʻaaogaina o le ED e faatatau i le faitau aofai o tagata, ma i lenei tulaga e leai se faʻamatalaga faʻapitoa
i aso masani o togafitiga faafomaʻi; faʻapea foi, e leai ni faʻamatalaga manino e maua e uiga i na tagata gasegase oeo loʻo sailia moni fesoasoani i le falemaʻi mo se faʻafitauli e fesoʻotaʻi ma le lelei o le fausiaina. I lenei itu, na matou taumafai ai e iloilo le masani ma le vaʻaia o le ED i alii talavou (faʻamalamalama faʻamalamalamaina ≤40 tausaga) o se vaega o le kulupu o le Caucasian mulimuli-Europa o loʻo sailia muamua fesoasoani faafomaʻi mo feusuaʻiga i feusuaiga i se tasi o aʻoga faʻapitoa.

Metotia

Faitau aofai

O suʻesuʻega sa faʻavae i luga o se kulupu o le 790 mulimuli Caucasian-Europa ole gasegase o gasegase e saili muamua fesoasoani faafomaʻi mo le faʻaleagaina fou o feusuaiga i le va o Ianuari Ianuari 2010 ma Iuni 2012 i se tasi o falemaʻi aʻoga faʻapitoa. Mo le faʻamoemoega patino o lenei suʻesuʻega suʻesuʻe, na o faʻamatalaga mai maʻi na faitioina ED. I lenei sini, ED ua faauigaina o le tumau pea le le mafai ona ausia pe tausia se fausaga talafeagai mo le lelei o le faia o feusuaiga [18].

O tagata gasegase sa iloiloina lelei ma se faʻamatalaga auiliili faʻamaʻi ma feusuaiga, e aofia ai faʻamatalaga i le sociodemographic. O faʻamalositino ma le faʻaogaina o le soifua maloloina na maua i le Charlson Comorbidity Index (CCI) [19] e le gata o se faʻaauau pea poʻo se faʻavasegaina faʻapitoa (ie, 0 vs. 1 vs. ≥2). Sa matou faaaogaina le Faʻavasegaga Faʻavaomalo o faʻamaʻi, Toe iloiloga 9th, Faʻaleleia o Falemaʻi. Faʻamaumauga o le numera o le tino (BMI),
faʻamalamalamaina o le mamafa i kilokalama i le maualuga i sikuea sikuea, na iloiloina mo tagata maʻi taitasi. Mo le BMI, matou te faʻaaogaina le vaʻaiga na fuafuaina e
o le National Institutes of Health [20]: mamafa masani (18.5-24.9), mamafa tele (25.0–29.9), ma le vasega ≥1 lapoʻa (-30.0). O le toto maualuga na faʻamatalaina ina ua ave vailaʻau antihypertensive ma / pe mo le toto maualuga (≥140 mm Hg systolic poʻo -90 mm Hg diastolic). O le Hypercholesterolemia na faʻamatalaina ina ua faia le lipid-lowering therapy ma / poʻo le maualuga-density lipoprotein cholesterol (HDL) cholesterol sa <40 mg / dL. E faʻapena foi, hypertriglyceridemia na faʻamatalaina a o plasma triglycerides o plasma150 mg / dL [21]. Polokalame faʻaleaʻoaʻoga a le National Cholesterol Education-Panel Panel Treatment III [21] taiala na faʻaaogaina i taimi uma e faʻamatala ai le faʻamaʻi o le gasegase o le metabolic (MeTs) i le vaega atoa o tagata ma ED.

Mo le mafuaʻaga faʻapitoa o lenei suʻesuʻega ma ia atagia mai ai le masani masani o le falemaʻi o meaola tau vailaʻau, na matou filifilia e fuaina le aofaʻi o testosterone (tT) tulaga e ala i le faʻaaogaina o auala faʻavasega avanoa. Hypogonadism na faʻamatalaina o tT <3 ng / mL [22].

Ona togafitia lea o tagata maʻi e tusa ai ma a latou sootaga (ua faauigaina o le "sootaga feusuai mausali" pe afai o le gasegase e tutusa le paaga
mo masina e ono pe sili atu; a leai "leai se mafutaga tumau" poo le nofofua). E faʻapea foʻi, na faʻateʻavaeina tagata gasegase e tusa ai ma o latou tulaga tau aʻoaʻoga i se vaega maualalo o aʻoaʻoga (e pei o aʻoaʻoga tulagalua ma aʻoga maualuga), se vasega maualuga o le aʻoga maualuga, ma i aliʻi e maualuga aʻoaʻoga (e pei o le iunivesite / le pasene).

E le gata i lea, na talosagaina ia gasegase e faamaea le Faasino Upu Faavaomalo o Erectile Function (IIEF) [23]; e tuʻuina atu se faʻavae mo le faʻamalamalamaina o le faʻamaoni ED, na matou faʻaogaina le faʻavaeina o le galuega IIEF-erectile e pei ona fuafuaina e Cappelleri et al. [24].

O faafitauli o le tusitusi tusitusi faapea foi isi faafitauli faitau ma tusitusi na le aofia uma i tagata gasegase.

Faʻamaumauga o faʻamatalaga na faia i le mulimuli i taʻiala o loʻo otooto atu i le Tautinoga o Helsinki; e sainia uma e le au gasegase se maliega faʻatagaina e malilie e tuʻuina atu a latou lava faʻamatalaga le iloa mo suʻesuʻega i le lumanaʻi.

Faʻamaumauga autu o taunuʻuga

O le vaega pito sili ona taua o lenei suʻesuʻega o le suʻesuʻeina lea o le faʻateleina ma le vaʻaia o le amataga o ED i alii talavou e sailia a latou fesoasoani muamua faafomaʻi
i le falemaʻi i aso taʻitasi, e tusa ai ma le faʻaaogaina masani o le 40 tausaga o tausaga. O le vaega lona lua o le suʻesuʻeina pe o le tulaga atoa o feusuaʻiga, e pei ona faʻasolosolo i le tele o le IIEF domains, sa ese le vaʻaia i alii laiti nai lo le 40 o tausaga pe a faatusatusa i tagata matutua.

Fuainumera Faamaumauga

Mo le mafuaʻaga faʻapitoa o lenei suʻesuʻega, o tagata mamaʻi ua iai le amataga o le ED ma saili muamua le fesoasoani faʻafomaʻi na faʻatulagaina i aliʻi 40 tausaga ma tagata taʻitasi> 40 tausaga le matutua. Faʻamaumauga faʻamaumauga na faʻaaogaina e faʻatusatusa ai faʻafomaʻi ma uiga lautele o le
lua vaega. O faʻamatalaga e tuʻuina atu o se uiga (fesuiaiga masani [SD]). O le taua o fuainumera o eseesega i uiga ma tulaga na iai
faʻataʻitaʻiina ma le lua-tailed t-suega ma le sikuea (χ2) suʻega, taʻitasi. Na faia suʻega faʻamaumauga e faʻaaoga ai le 13.0 (IBM Corp., Armonk, NY, ISA). O suʻega uma e lua itu, ma se tulaga taua i 0.05.

i'uga

Fou onset ED o le muamua faʻamaʻi na maua i 439 tagata mamaʻi (55.6%) mai 790 tagata mamaʻi. I latou, 114 (25.9%) sa ≤40 tausaga. Laulau 1 auiliiliga o uiga tau tagata tagata ma fuainumera faʻamatalaga o le kulupu atoa o tagata gasegase ma le ED, e pei ona faʻamavaeina e tusa ai ma le faʻasalaga o tausaga o le 40 tausaga. I lenei tulaga, o gasegase ≤40 tausaga o le matua i le taimi na latou uluai sailia ai fesoasoani faafomaʻi mo ED na faʻaalia ai
Ole maualuga ole fua ole ala (ole mea na ausia i le CCI), o le tau maualalo ole BMI, o se vaega maualalo o tagata taitoatasi ole BMI e fautuaina ai le mamafa ma le vasega ≥1 isesa, o le maualuga o le maualuga o le toto maualuga ma le hypercholesterolemia, ma le maualuga o le faasalalau tT level pe a faatusatusa i latou matutua nai lo le 40 tausaga (uma P ≤ 0.02). I se isi itu, e leai ni eseesega na matauina i le va o kulupu i tulaga o fua faatatau o hypertriglyceridemia, MetS, ma hypogonadism (Lisi 1). E le gata i lea, o le au Epikopo ED e sili atu le maualuga o le faʻafeusuaiga faʻafeusuaiga ma se vaega maualalo o feusuaiga faʻafeusuaiga (uma P  ≤ 0.02). Leai ni eseesega taua na matauina e tusa ai ma le tulaga aʻoaʻoga i le va o kulupu. O se maualuga maualuga fua faatatau o comorbid vave osovale (a le olaga atoa pe maua) na matauina i talavou gasegase nai lo matutua tagata; I se isi itu, o le faʻamaʻi o Peyronie sa tele na iai i le vaega matutua (uma P = 0.03), e ui lava e leai ni eseesega i le taatele o le maualalo o manaʻoga feusuaiga i le va o vaega e lua (Laulau 1).

Laulau 1. Faʻamaumauga faʻamaumauga i ≤40 tausaga le matua ma> 40 tausaga ED tagata mamaʻi (Nu = 439)
 Tagata maʻi ≤40 tausagaTagata mamaʻi> 40 tausagaP tāua*
  1. Ki:
    SD = fetuunaiga masani; CCI = Charlson Comorbidity Index; BMI = tino
    pine tele; NIH = National Institutes of Health; MeTs = Metabolic
    maʻi; tT = aofaʻi testosterone; PE = faʻasologa vave

  2. *P tau faʻatatau e tusa ma le χ2 suega pe lua tutoatasi t-test, pei ona faailoa mai

Leai o gasegase (%)114 (25.9)325 (74.1) 
Tausaga (tausaga; uiga [SD])32.4 (6.0)57.1 (9.7)
mamao17-4041-77
CCI (Nu. [%])  <0.001 (χ2, 39.12)
0103 (90.4)189 (58.3) 
16 (5.3)62 (19)
2+5 (4.4)74 (22.7)
BMI (kg / m2; uiga [SD])25.1 (4.1)26.4 (3.7)0.005
BMI (faʻavaeina o le NIH) (Leai [%])  0.002 (χ2, 15.20)
1 (0.9)0 (0) 
18.5-24.963 (56.5)126 (38.7)
25-29.934 (29.6)157 (48.3)
≥3016 (13)42 (13)
Maualuga maualuga (Leai [%])6 (5.3)122 (37.5)<0.001 (χ2, 42.40)
Hypercholesterolemia (Leai [%])4 (3.5)38 (11.7)0.02 (χ2, 5.64)
Hypertriglyceridemia (Numera [%])0 (0.0)10 (3.1)0.12 (χ2, 2.37)
MeTs (Leai [%])2 (1.8)10 (3.1)0.57 (χ2, 0.74)
tT (ng / mL; uiga [SD])5.3 (2.0)4.5 (1.8)0.005
Hypogonadism (aofaʻi <3 ng / mL) (Nu. [%])12 (10.3)54 (16.6)0.14 (χ2, 2.16)
Faʻasalaga feusuaiga (Nu. [%])  0.02 (χ2, 5.66)
Faʻafeusuaiga109 (95.6)322 (99.1) 
Faʻafeusuaiga5 (4.4)3 (0.9)
Sootaga o sootaga (Numera [%])  <0.001 (χ2, 27.51)
Feusuaʻiga tau feusuaʻiga ≥6 masina81 (71.4)303 (93.2) 
Leai se feusuaiga masani33 (28.6)22 (6.8)
Tulaga tau aʻoaʻoga (Nu. [%])  0.05 (χ2, 9.30)
Aoga Maualuga0 (0)22 (6.8) 
Aoga maualuga20 (17.5)64 (19.7)
Aoga maualuga51 (44.7)141 (43.4)
Faʻasaienisi43 (37.7)98 (30.2)
Faʻasalaga feusuaʻiga malie (Nu. [%])   
PE14 (12.4)20 (6.2)0.03 (χ2, 4.55)
Low libido10 (8.8)23 (7.1)0.55 (χ2, 0.35)
Peyronie maʻi5 (4.4)37 (11.4)0.03 (χ2, 4.78)

laulau 2 lisiina fualaʻau na ave e tagata mamaʻi o vaega e lua, vavae ese e le aiga o vailaʻau. Faʻapena foi, Lisi 2 ma faʻamatalaga auiliili mea faʻafiafia na lipotia mai e gasegase ma
vaevaeina e le matua. O tagata matutua matutua o ED sa masani ona latou aveina
vailaʻau faʻasaina mo aiga taʻitasi faʻapea foʻi ma thiazide
togafitiga ma le lipid-lowering drugs e faatusatusa i alii ≤40 tausaga (uma P
≤ 0.02). E faapena foi, o tagata matutua matutua e masani ona latou aveina foi
vailaʻau faufau ma vailaʻau faʻamaʻi, alpha-blockers mo LUTS, ma proton
pamu pupuni e faatusatusa i alii talavou (uma P ≤ 0.03).

Laulau 2. Vailaʻau faʻamalositino ma masaniga faʻafiafia i ≤40 tausaga ma> 40 tausaga ED tagata mamaʻi - (Nu. = 439)
 Tagata maʻi ≤40 tausagaTagata mamaʻi> 40 tausagaP tāua*
  1. Ki:
    ACE-i = angiotensin-liua tagata inhibitors o le enzyme; SNRI = serotonin ma
    nohibitrenail reuptake inhibitors; SSRIs = toe filifilia serotonin reuptake
    inhibitors; BPH = hyperplasia le maualuga o le prostatic; LUTS = maualalo ifo urinary
    faʻailoga

  2. *P tau faʻatatau e tusa ma le χ2 suega pe lua tutoatasi t-test, pei ona faailoa mai

Leai o gasegase (%)114 (25.9)325 (74.1) 
Faʻaaoga fualaau faʻamaʻi   
ACE-i1 (0.9)47 (14.5)<0.001 (χ2, 14.62)
Angiotensin-II tagata talitutusa2 (1.8)41 (12.6)0.002 (χ2, 9.95)
Beta-1 poloka2 (1.8)44 (13.5)0.0009 (χ2, 11.12)
Paʻu o le kesi0 (0.0)39 (12.0)0.002 (χ2, 13.57)
Diuretics   
Luga totogo0 (0.0)6 (1.8)0.33 (χ2, 0.94)
Thiazide diuretics0 (0.0)18 (5.5)0.02 (χ2, 5.20)
Isi vailaʻau cardiovascular   
Digoxin0 (0.0)7 (2.2)0.24 (χ2, 1.36)
Antiarrhythmic drugs1 (0.9)6 (1.8)0.82 (χ2, 0.05)
Vailaʻau faʻamaʻi1 (0.9)10 (3.1)0.35 (χ2, 0.89)
Antiplatelet fualaau faasaina1 (0.9)1 (1.8)0.82 (χ2, 0.06)
O vailaʻau faʻasusu i lalo ole lipid (statins & / poʻo fibrates)0 (0.0)43 (13.2)0.0001 (χ2, 15.21)
Ogatotonu o fualaau oona   
Fualaau faʻatau1 (0.9)6 (1.8)0.82 (χ2, 0.05)
Faʻasalalauga0 (0.0)2 (0.6)0.99 (χ2, 0.00)
Benzodiazepine2 (1.8)15 (4.6)0.29 (χ2, 1.11)
Neuroleptics2 (1.8)3 (0.9)0.79 (χ2, 0.07)
Opioid fualaau faasaina0 (0.0)2 (0.6)0.99 (χ2, 0.00)
SNRIs1 (0.9)1 (0.3)0.99 (χ2, 0.00)
SSRIs8 (7.0)8 (2.5)0.06 (χ2, 3.65)
Endocrinological fualaau faasaina   
Vaʻaia Antiandrogenic0 (0.0)3 (0.9)0.73 (χ2, 0.12)
Antithyroid fualaau faasaina0 (0.0)1 (0.3)0.57 (χ2, 0.33)
Thyroxin2 (1.8)17 (5.2)0.20 (χ2, 1.61)
Corticosteroids3 (2.6)12 (3.7)0.80 (χ2, 0.07)
Darbepoetin0 (0.0)1 (0.3)0.57 (χ2, 0.33)
Desmopressin0 (0.0)2 (0.6)0.99 (χ2, 0.00)
Dopamine agonists2 (1.8)4 (1.2)1.00 (χ2, 0.00)
Dopamine4 (3.5)3 (0.9)0.14 (χ2, 2.19)
Vailaʻau oona   
Antidiabetic drugs3 (2.6)32 (9.8)0.02 (χ2, 5.05)
Inisalini3 (2.6)23 (7.1)0.13 (χ2, 2.31)
Mafuli o fualaau oona   
Antihistamines4 (3.5)12 (3.7)0.85 (χ2, 0.04)
Beta2-agonist1 (0.9)3 (0.9)0.56 (χ2, 0.33)
BPH / LUTS-fualaau faʻatau   
5-alpha reductase inhibitors1 (0.9)6 (1.9)0.77 (χ2, 0.09)
Alpha-blockers1 (0.9)41 (12.6)0.0005 (χ2, 12.04)
Isi fualaau   
Anticholinergic fualaau faasaina1 (0.9)1 (0.3)0.99 (χ2, 0.00)
Immunomodulators / immunosuppressors3 (2.6)12 (3.7)0.80 (χ2, 0.07)
Prohibit pommo inhibitors2 (1.8)33 (10.2)0.008 (χ2, 6.98)
Noncoroidal anti-inflammatory drugs7 (6.1)14 (4.3)0.60 (χ2, 0.27)
Triptans0 (0.0)1 (0.3)0.57 (χ2, 0.33)
vaitamini2 (1.8)11 (3.4)0.59 (χ2, 0.30)
Uricosuric fualaau0 (0.0)17 (5.2)0.03 (χ2, 4.84)
    
Fuʻu ulaula (No [%])  0.02 (χ2, 7.56)
Tagata ulaula oi ai nei43 (37.8)80 (24.6) 
Tagata ulaula na muamua1 (0.9)7 (2.2)
Aua nei ulaula70 (61.3)238 (73.2)
Alu ava (soʻo se vol / vaiaso) (Leai [%])  0.52 (χ2, 0.41)
Faʻaauau88 (77.2)262 (80.6)0.16 (χ2, 1.93)
Alu ava (1-2 L / vaiaso)26 (22.8)98 (30.2)0.96 (χ2, 0.00)
Inu 'ava malosi (> 2 L / vaiaso)4 (3.6)10 (3.1) 
Faʻasologa o fualaau faasaina (soo se ituaiga) (Leai [%])24 (20.9)11 (3.4)<0.001 (χ2, 34.46)
Cannabis / mariuana24 (20.9)9 (2.8)<0.001 (χ2, 37.29)
Cocaine4 (3.5)0 (0.0)0.005 (χ2, 37.29)
Heroin0 (0.0)3 (0.9)0.73 (χ2, 7.92)

E leai se eseesega na maua mo se isi aiga o fualaʻau (Laulau 2).

Itiiti
O faʻataʻitaʻiga a le ED e masani ona faʻaalia se masaniga o ulaula sikaleti
ma le faʻaaogaina o fualaau faasaina (uma cannabis / mariuana ma cocaine) e pei
pe a faatusatusa i alii matutua nai lo 40 tausaga (uma P ≤ 0.02). Leai ni eseesega na maua i tuutuuga o le inu ava i le va o kulupu (Laulau 2).

laulau 3 auiliiliga auupega (SD) scores mo le lima vaega o le IIEF sikola; leai
eseʻese taua na matauina mo soʻo se itu IIEF i le va o
laiti ma sili atu le fou fou o tagata maʻi ED. E faʻapea foʻi, alii ≤40 tausaga
na faʻaalia ai le tutusa ma le tele o le faʻaogaina o le ED ogaoga pe a faatusatusa
ma tagata matutua matutua. E faapena foi, fua faatatau o le agamalu, agamalu, ma le agavaʻa, ma
ED le lelei e leʻi ese tele i le va o vaega e lua
(Laulau 3).

Laulau 3. IIEF-numera togi ma fua faatatau o ED faigata i ≤40 tausaga ma> tausaga ED tagata mamaʻi (Nu = 439)
IIEF-domains (uiga [SD])Tagata maʻi ≤40 tausagaTagata mamaʻi> 40 tausagaP tāua*
  1. Ki:
    IIEF = Faʻamatalaga Faʻavaomalo o le Erectile Function; EF = Erectile Function
    fanua; IS = fesoʻotaʻiga vavalalata; OF = faʻamalositino galuega
    fanua; SD = manaʻo feusuaʻiga domain; OS: tulaga faamalieina uma;
    ED = erectile ua le afaina

  2. *P taua e tusa i le lua-siʻu Tamaiti Aʻoga t-test po o le χ2 suega, e pei ona faʻaalia

  3. † O le malosi o le ED na faʻavasegaina e tusa ai ma le faʻavasegaina na fautuaina mai e Cappelleri et al. [23].

IIEF-EF12.77 (8.7)14.67 (8.4)0.23
IIEF-IS5.9 (4.2)6.69 (4.1)0.33
IIEF-OF7.51 (3.2)7.06 (3.5)0.49
IIEF-SD6.98 (2.3)6.57 (2.1)0.36
IIEF-OS4.95 (2.6)5.06 (2.5)0.82
Malosi IIEF (Leai [%])   
Normal EF11 (9.3)39 (11.9)0.73 (χ2, 2.01)
Laititi ED16 (14.0)55 (16.8)
Laititi agavaʻa faʻalelei ED10 (9.3)51 (15.8)
Faʻalelei ED21 (18.6)48 (14.9)
Sini malosi ED56 (48.8)132 (40.6)

Talanoaga

We
ua toe iloiloina ma le toe iloilo se vaega o le Caucasian-European
tagata gaioiga faʻafeusuaiga e sailia muamua fesoasoani faafomai mo le fou fou ED i le
tasi faʻataʻitaʻiga i fafo atu o le vaitaimi o le 30-masina ina ia
Iloilo tulaga masani ma uiga o tagata taitoatasi ≤40 tausaga e pei o
pe a faatusatusa i latou o tagata matutua nai lo le 40 tausaga i le taimi o le ED.
Na matou iloa o le tasi mai le toafa o alii ma ED e laʻititi nai lo le 40 tausaga.
E le gata i lea, o se faʻatusatusaga talitutusa o talavou laiti ma matutua atu ED
faitioina le ogaoga o le ED. E faʻapea foi, o tamaiti laiti ma sili atu ona gasegase tutusa
sikola mo vaega IIEF, e aofia ai le manaʻoga feusuaʻiga, mea faʻapitoa
galuega, ma le atoa o le faamalieina. O le mea lea, o le matauina o se
na foliga uma mai ia i matou o se ata popole mai le falemaʻi i aso faisoo
faiga masani.

ED o se tulaga ma
tulaga faʻamaonia faʻamaonia ma le sociodemographic faʻamatalaga na iai
iloiloga lautele i suʻesuʻega eseese [7-10, 13, 14, 25]. I le aotelega, o le tausaga ua manatu o le sili ona taua, faatasi ai ma le tele o suesuega ua faaalia ai le faateleina o ED ma tausaga [7, 8, 26];
mo se faʻataʻitaʻiga, o faʻamatalaga mai le Massachusetts Male Aging study ua maeʻa
o lena tausaga o le fesuiaiga sili ona malosi e fesootai ma ED [7]. E ese mai i le matua, o le tele o isi fomaʻi ua malosi lona aʻafia ma ED [7, 10, 12-14, 26].
I le vaitaimi o le matua, o tane e masani ona mafatia mai le tasi
po o le sili atu foi o tulaga ua taʻua i luga ma le, ae leai
O le mea e ofo ai, e masani ona latou faitioina foi ED. Mo nei mafuaʻaga, o le tele o
o suʻesuʻega a le Epidemiology e fesoʻotaʻi ma le faʻaaogāina o le ED ma tagata vavalo
ua faia i totonu o se faitau aofaʻi o tagata e sili atu le matutua nai lo 40 tausaga;
i se isi itu, na o ni nai suʻesuʻega e aofia ai faʻamatalaga mai le laʻititi
tagata taitoatasi [14-16, 26, 27].
I le aotelega, o faʻamaumauga mai nei suʻesuʻega mulimuli ane na faʻaalia ai e le o se mea e le masani ai ED
tulaga e oo lava i alii talavou. Mo se faʻataʻitaʻiga, na lipotia mai Mialon et al
o le faʻaaogaina o ED o le 29.9% i totonu o se 'autau o alii talavou Suiselani [15]. E faapena foi, Ponholzer et al. [14] maua fua tutusa o ED i se faasologa faʻasalalau o tamaʻitaʻi 20-80
tausaga o auai i se poloketi o le soifua maloloina i le vanu o Vienna.
E faapena foi Martins ma Abdo [16] faʻaaogaina faʻamatalaga mai se suʻesuʻega faʻasalalauga lea o loʻo i ai 1,947 tane o tausaga 18-40 tausaga
tuai na faʻafesoʻotaʻi i nofoaga faitele o 18 tele aai Pasila ma
faatalanoaina e faaaoga ai se fesili e leiloa; Aotelega, 35% o na mea
tagata taʻitasi ua lipotia nisi o togi o faigata faʻa-ereilela.

A
malosi tele o la tatou auiliiliga e afua mai i le mea moni e saʻo lava
Iloiloina le taatele ma uiga o ED i alii talavou ua faaopoopoina
mai se kulupu o gasegase na sosoo mai i le matou falemai
falemaʻi e sailia muamua fesoasoani faafomaʻi mo ED; i lenei tulaga, na ma mauaina lena mea
kuata o tagata gasegase o loʻo mafatia i le ED i le faiga masani o togafitiga
oi latou o loʻo i lalo o le 40 tausaga. O lenei mea ua faamaonia manino i aso ua tuanai
faʻamatalaga faʻamaʻi mai le suʻesuʻeina o tagata, ma faʻaalia ai lena mea
ED e le naʻo se faʻaletonu o le matua o le matua ma lena faʻatulagaga erectile
o le le atoatoa i alii talavou e le tatau ona manatu faatauvaa. Matou
faʻamatalaga o faʻataʻitaʻiga o faʻasologa i aso uma e sili atu mea e faatatau i ai
mafaufau i le masani a le tele o fomaʻi e leai
masani i le soifua maloloina o alii ma tamaitai; ioe, ona o le maualalo
fua faatatau o le ED e suʻesuʻeina e fomaʻi lautele i tagata gasegase e sili atu nai lo
40 tausaga [28], matou te fefefe tele e faapea o le ED po o le gaioiga faʻafeusuaiga i se tasi e mafai ona oʻo lava i le itiiti ifo o le suʻesuʻeina i alii talavou [29].

le
o suʻesuʻega o la tatou suʻesuʻega na faʻaalia ai o tagata gasegase laʻititi i le lalolagi atoa
sili atu le soifua maloloina pe a faatusatusa i alii matutua nai lo le 40 tausaga, faʻaalia lalo CCI
sikoa-faatasi ai ma se numera itiiti o fualaau, aemaise lava mo
CVDs, o le BMI maualalo maualalo, ma le faʻaititia o le maualuga o le maualuga.
E tutusa foi, ma e le o le mea e ofo ai, o tagata laiti e maualuga le uiga o le tT
maualuga pe a faatusatusa i tagata mamaʻi e sili atu nai lo le 40 tausaga, o lea e faʻapipiʻi ai
o le tele o suʻesuʻega a le Epidemiological i tagata matutua o Europa [2].
I le aotelega, o nei faʻamaoniga faʻamaumauga e faʻamaonia ai i latou na maua mai le
Pasili a Pasila, lea na le mafai ona maua soʻo se fegalegaleaiga taua ma
faʻamaonia faʻamaonia tulaga faʻapitoa mo mea faʻaleagaina e pei o le maʻisuka ma le CVD i alii
tausaga 18-40 tausaga matua [16].
I le aotelega, o nei eseesega na faʻamoemoeina, ma tuʻuina atu le mea moni e faapea ED i
o alii talavou e masani lava ona fesootai i le tele o mafaufauga ma
mea faʻapitoa e masani ona avea ma mafuaʻaga autu
[8, 30, 31]. E le gata i lea, o Mialon et al. [15] na faaalia ai o le eseesega tele i le va o le talavou ma le matutua ED tagata
mafaufau maloloina ma mafaufau e uiga i vailaʻau. I la matou vaega o ED
gasegase, matou iloa ai o alii talavou e masani ona masani ona fai ma vaisu
ulaula sikaleti ma fualaau faasaina (ie, cannabis / mariuana ma
cocaine) nai lo tagata matutua. Faʻamaumauga muamua i le faʻaaoga masani o
fualaau faasaina-aemaise lava cannabis, opiates, ma cocaine-ua faaalia leai
molimau le mafaamatalaina o se sootaga ma ED [32-34],
ma e mautinoa lava o nisi o faʻamatalaga na fautuaina mai ai se mafuaʻaga taua mo
ulaula tapaa ulaula i le faʻalauiloaina o le faʻaleagaina o galuega faʻaleagaina e oʻo lava i
i talavou [7, 34-37].
Ona o le natura faʻamatalaga oa tatou suʻesuʻega, tatou te le mafai ona manatu
pe afai o nei uiga o le soifuaga mulimuli e mafai ona fesoʻotai manino ma le
amataina ED i alii talavou, ae e mautinoa lava le talafeagai i le faʻamaonia
ia mafai ei laua uma ona faia se sao faatasi ma isi mea taua
faalauiloaina le faaleagaina o galuega erectile. I se isi itu, o lenei taimi masani
mea ua fai ma vaisu i mea faafiafia-lea atonu e mafai foi
leaga e le gata mo le soifua maloloina tau feusuaʻiga-atili faʻamalosia le popolega o le
faʻavae e mafua mai i le maitauina, o lona uiga, o le kuata o alii oe
sau e saili muamua fesoasoani mo ED i lalo ole 40 tausaga, ma e masani ona lipoti
faʻaaoga masani o fualaau leaga, e masani lava e le tusa ai ma le tulafono.

mulimuli ane,
matou te iloiloina ma le mafaufau le fua o le malosi o le ED i vaega uma e lua;
o faʻatusatusaga tutusa o le ED faʻaleagaga na maua i le va o vaega. O
taua tele, toetoe o le afa o tagata taitoatasi i lalo ole 40 tausaga
na pagatia i le ogaoga o le ED e tusa ai ma Cappelleri et al. [24],
o lenei tulaga e matua tutusa lava ma le mea na matauina i alii matutua.
I lo matou manatu, o lenei sailiiliga o le a iu lava ina fautuaina e faapea
le faʻaleagaina o le faʻatuina e mafai ona manatu e le aoga i le laʻititi
gasegase e pei o alii matutua, o le mea lea o le lagolagoina o le mea moni o lenei feusuaiga
faafitauli e tatau ona lava le gauai atu i togafitiga i aso taitasi i
tausaga uma. E faapena foi, matou te iloiloina pe o le a le talavou ma le matutua ED
na ausia i le tulaga o le gaioiga masani o feusuaiga, e pei ona faʻamatalaina e faʻaaoga ai le
eseese vaega ole IIEF. E ogatasi ma faʻamaumauga muamua o loʻo faʻaalia ai
suiga i taimi umi i le lima vaega o feusuaʻiga mataʻitu e suʻe faatasi
ova taimi [38],
matou te leʻi matauina soʻo se eseesega taua i vaega taitasi IIEF
i le va o vaega. I lenei tulaga, o le a mafai ona masalosalo lena mea,
e tusa lava pe i ai mafuaʻaga autu o mafuaʻaga mo ED, e le mafai ona faia le meafaigaluega IIEF
mafai ona faʻamaonia saʻo le pathophysiology i tua ole ED. Ioe,
e ui lava ED, e pei ona faaliliuina ma le moni ile galuega IIEF-erectile
vaega, ua faʻataʻitaʻiina i le faʻamatalaga mo se CCI maualuga, atonu e ono
ua manatu o se sui faʻatuatuaina o tulaga maualalo o le soifua maloloina lautele,
tusa lava po o le a le uiga o le ED [3], Deveci et al. [39] na le mafai ona faʻaalia i le taimi muamua e mafai e le IIEF ona mafai
faʻasesega i le va o mea faʻapitoa ma le mafaufau mafaufauga ED. Ae peitai, o le
e moni lava o se numera o suʻesuʻega na fautua mai e mafai e ED ona avea
faʻamatalaga lautele o mea CVD [40, 41]. Faatasi ai ma i latou, Chew et al. [41],
mo se faʻataʻitaʻiga, suʻesuʻe ED e avea o se tagata vaʻai i mea CVD i a
aofaʻi o tane ma ED i le va o 20 ma 89 tausaga o le matutua; nei
na maua ai e tusitala se tulaga sili atu ona aʻafia mo mea CVD i tagata maʻi ED
laʻititi nai tausaga 40. I se isi itu, o se faʻaititia o le taua o le ED
aua o mea na tutupu i le CVD na matauina i le matutua o tagata [41].
I le aotelega, o nei faʻamaumauga muamua ma o tatou suʻesuʻega oi ai nei e mafai ona fautua mai
o le iloiloga ED o se auala taua lea e iloa ai talavou ma
tagata ogatotonu o loʻo avea ma sui taualoa mo lamatiaga cardiovascular
iloiloga ma togafitiga faafomaʻi mulimuli ane. E tusa lava pe o le tele o
o gasegase i lenei vaitausaga atonu o le a ono mafatia mai le ED,
e mafai ona i ai se vaega o latou faitioga o le ED eletise o
fesuiaiga lautele o alaleo, ma ED o le na o le pau lea o le faailoga mo se
faʻaleagaina o le soifua maloloina (ie, atherosclerosis). I lenei
context, Kupelian et al., mo se faʻataʻitaʻiga, suʻesuʻeina se faitau aofaʻi o tagata 928
e aunoa ma le MeTs, na faʻaalia ai o le ED na tauva mo le atinaʻe mulimuli ane
MeTS i tagata gasegase e masani ai le BMI masani i le laina [42],
faʻapea le faʻamalosia o le taua o ED o se mataupu e fesoasoani e faʻamalosia alii talavou
ia i ai se olaga soifua maloloina umi, lea e mafai ona suia ai le tulaga lamatia o
faamai e pei o le maʻisuka ma le CVD, faatasi ai ma isi.

O lo tatou
suʻesuʻega e leʻo iai ni tapulaa. Muamua, o la matou vaega laʻititi laiti
o tagata e mafai ona faʻatapulaʻaina le uiga oa tatou mea na maua, ao tatou faia
na o na tagata gasegase sa faʻaaogaina i vailaau faʻafeusuaiga
falemaʻi ile falemaʻi e mafai ona faʻamaonia se faʻafitauli ole filifiliga i tulaga faigata
o le ED, ma mafua ai ona misia se numera o tagata taitoatasi ma le ED vaivai ma
itiiti le faaosofia e saili fesoasoani faafomaʻi. Peitai, matou te manatu o lenei mea
o le a tutusa lava le tutusa o le faʻaogaina o mea sese i vaega uma e lua, o lea
e le faʻaleagaina ai le taua o nei sailiga. Lona lua, matou te leʻi iloiloina
fua o le atuatuvale po o le popole e ala i le faʻaaogaina o meafaifaʻaili a le psychometric.
I lenei tulaga, o le mafuaʻaga mafuaʻaga i le va o ED ma le isi
atuatuvalega po o popolega, po o mea uma e lua, atonu o se pule; ioe, ED
e mafai ona maua pe a uma le faʻaleagaina poʻo le atuatuvale lea, i le isi itu, atonu
o se taunuuga o soʻo se faʻafeusuaiga. Le i ai o se meafaigaluega e mafai
Faʻailogaina lenei tulaga e mafai ona sili atu lona aoga
aemaise lava i le tupulaga talavou. Tolu, oa tatou auiliiliga e leʻi
faʻapitoa iloiloina gasegase 'feusuaʻiga talaʻaga ma feusuaiga i luga o le
tausaga talavou. I lenei tulaga, Martins ma Abdo [16] na faʻaalia le leai o se faʻamatalaga e uiga i feusuaiga i tamaʻi tino laiti
fesoʻotaʻi ma le ED ona o le fefe ma masalosaloga na faʻatulai mai e taboos
ma mea e le masani ai. Tagata maʻi ma faigata i le taimi atoa
amataina o la latou feusuaʻiga faʻaalia le maualuga atu o ED, masalo
e mafua mai i se taamilosaga o le popole ma le toilalo e iu lava ina faaleagaina ai le
feusuaiga a le tagata [43].
Ma le mea mulimuli, o la matou suʻesuʻega e le amanaia ai le tamaoaiga
vaega o le olaga; ioe, o le tele o tupe maua a le aiga na faʻaalia i
ia fesoʻotaʻi lelei ma amioga faʻatau togafitiga, ae
faaletonu tau tupe atonu o le a avea ma sui o se pa puipui [44].
Ae peitai, matou te filifili, e le o talosagaina faamatalaga maua mai le maualalo
tali vave i fesili maua mai e masani ona tatou maua i le olaga moni
togafitiga faafomaʻi ao faagasolo asiasiga o le ofisa.

faaiuga

In
faʻatusatusa i mea ua lipotia mai e le faitau aofaʻi o suʻesuʻega o le
faʻaaogaina o le ED i tagata gasegase, o mea na matou maua e faʻaalia ai e tasi le tasi
tagata e toʻafitu o loʻo sailia fesoasoani faafomaʻi mo ED i le faiga masani o le falemaʻi i aso taitasi
o se falemaʻi i fafo o se alii talavou i lalo o le 40 tausaga. E le gata i lea,
toetoe o le afa o alii talavou na pagatia i le ED ogaoga, o le mea lea
tutusa e tutusa ma lena na matauina i tagata matutua. Agai i
o faʻataʻitaʻiga o falemaʻi i aso taʻitasi, o suʻesuʻega o loʻo maua i le taimi nei e faʻamalosia ai i matou e faʻatele
otootoina le taua o le faia o se vailaau ma togafitiga atoatoa
talafaasolopito ma faia se suʻesuʻega faʻapitoa maeʻaeʻa i tagata uma
ED, tusa lava po o le a le matutua. E faapena foi, ona o le maualalo o le sailia
fesoasoani faafomaʻi mo faʻafitauli e fesoʻotaʻi ma le soifua maloloina o feusuaiga, o nei taunuuga
faʻaalia atili le manaoga o tagata tausi soifua maloloina e mafai ona fesili faʻamalosi
e uiga i feusuaiga e ono faia ai feusuaiga, i le taimi e tasi e oʻo lava i alii nai lo
40 tausaga le matua. Talu ai o le faʻataʻitaʻiga o loʻo i ai nei e tapulaa, masalo matou
e le mafai ona maua faaiuga lautele; o le mea lea, o suʻesuʻega faaopoopo i
o faʻataʻitaʻiga e sili atu i le faitau aofaʻi e manaʻomia e faʻamaonia ai nei taunuuga ma
ia faʻamaonia atili le tulaga gafatia o le malosi o le ED e pei o se taʻavale
o faʻafitauli fomaʻi i alii i lalo ifo o le 40 tausaga.

Feeseeseaiga o Tului: E leai ni feteenaʻiga e fiafia ai tusitala.

Faamatalaga o le Tusitala

Category 1

  • (a)
    Fuafuaga ma Fuafuaga
    Paolo Capogrosso; Andrea Salonia
  • (b)
    Faʻatauga o Faʻamatalaga
    Michele Colicchia; Eugenio Ventimiglia; Giulia Castagna; Maria Chiara Clementi; Fabio Castiglione
  • (c)
    Iloiloga ma le Faamatalaina o Faamatalaga
    Nazareno Suardi; Andrea Salonia; Francesco Cantiello

Category 2

  • (a)
    Tusiaina o le Mataupu
    Paolo Capogrosso; Andrea Salonia
  • (b)
    Toe Iloiloina mo le Atinaʻeina o le Mafaufau
    Andrea Salonia; Alberto Briganti; Rocco Damiano

Category 3

  • (a)
    Faamaoniga Mulimuli o le Mataupu ua maea
    Andrea Salonia; Francesco Montorsi

mau faasino