Biol Psychol. 2010 Sep;85(1):33-7. doi: 10.1016/j.biopsycho.2010.04.008.
Lobo DS1, Souza RP, Tong RP, Casey DM, Hodgins DC, Samita GJ, Williams RJ, Schopflocher DP, Wood RT, el-Guebaly N, Kennedy JL.
lē faʻatino
Pathological gambling (PG) ose fa'aletonu e pulea ai lagona fa'atupu fa'alavelave fa'atasi ai ma vaega fa'aletonu fa'atupu fa'agatama. Na matou iloiloina le fesoʻotaʻiga o fesuiaiga o kenera i le dopaminergic receptor genes (DRD1-3s) ma le lamatiaga mo taaloga faitupe i mataupu soifua maloloina e faʻaaoga ai le Canadian Problem Gambling Index (CPGI). O mataupu Caucasian soifua maloloina oe na taaalo pe a ma le tasi i le olaga atoa (n=242) na aofia i le auiliiliga. E le'i feso'ota'i le itupa ma le CPGI, a'o la'ititi la'ititi na feso'ota'i ma togi maualuga o le CPGI. Ua matou iloa e leai se tasi o polymorphisms e tasi na suʻesuʻeina ile DRD1 ma le DRD3 e fesoʻotaʻi ma CPGI togi i mataupu soifua maloloina. Ae ui i lea, na matou matauina faiga mo faʻatasi i le TaqIA / rs1800497 polymorphism (P = 0.10) ma le haplotype flanking DRD2 (G / C / A rs11604671 / rs4938015 / rs2303380; P = 0.06). O faiga uma e lua na fesoʻotaʻi ma le togi maualalo o le CPGI. O a matou taunuʻuga o loʻo tuʻuina atu ai faʻamaoniga atili mo le matafaioi o le dopamine D2-pei o le talipupuni i le faʻaogaina o vaisu.
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