Neuropsychopharmacology. 2018 Oct 6. doi: 10.1038 / s41386-018-0235-1.
Kuiper LB1, Faʻafetai LN1, Dupuy BM1, Coolen LM2,3.
lē faʻatino
O le agavaʻa e atiaʻe ai mea ua fai ma vaisu ua aʻafia i le tele o mea, e aofia ai amio faʻalapotopotoga. E patino lava, i tagata e faʻaaogaina tagata, o le tagofiaina o fualaau faʻatau i se sosaiete faʻafeusuaiga e faʻaalia ai le faʻaleleia atili o le faʻataʻitaʻiina o amioga faʻatau. Lipoti a le aufaʻatauloa ua faʻateleina le fiafia i feusuaiga e avea o se faʻamalosi mo le faʻaaoga atili o fualaau oona ma faʻaalia amio faʻaletonu e tusa lava pe a tofotofoina i le tulaga e leai se fualaau. I lenei, e faʻaaogaina ai se faʻataʻitaʻiga o le faʻatapulaʻaina o fualaau faʻatau fua i tama, na tofotofoina le vaʻaia e methamphetamine (Meth) faʻatasi ma le faʻalauteleina o feusuaiga ma feusuaiga e faʻateleina ai le faʻafitauli i vaisu. O tama Sprague Dawley sa nonofo faʻasalalau ma faʻatapulaʻaina le avanoa mo le puleaina o Meth (maualuga 1 mg / kg / vasega). O Meth-taking e tutusa pe leai foi ma amioga tau feusuaiga: o tamaʻitaʻi faʻatasi ma le fafine faʻafeiloaʻi i le taimi lava e maeʻa ai sauniga taʻitasi, ae o manu e le tutusa, na maua tutusa aafiaga tau feusuaʻiga i le vaiaso muamua. I le isi itu, o fua o fualaau faasaina na fuaina i le taimi o le faʻafoʻiina, faʻaaogaina, ma toe faʻaleleia sauniga e faʻaaoga ai faʻasalalauga eseese ma toe faʻaleleia i 4 suʻesuʻega eseese. O vaega uma e lua na tutusa lava le mauaina o le pule a le Meth ma e le eseese i le atoaga o le tupe a Meth. Ae ui i lea, o le faʻataʻitaʻiina o amioga fualaau faasaina na sili atu le maualuga i manu tutusa i le taimi o gaioiga o gaioiga faʻaalia, faʻasalaga faʻasalaga, ma suʻega a le Meth-induced reitement tests. E le gata i lea, o amioga tau feusuaiga i le toesea o Meth na mafua ai le toe faʻaaogaina o fualaau faʻasaina i manu tutusa. O nei taunuʻuga e faʻamaonia ai o Meth-faʻataʻitaʻi i se faʻalapotopotoga faʻa-va fealoai ma faʻafeusuaiga e sili atu le faʻaleleia o le tulaga lamatia mo le tagofiaina o fualaau oona i tama tane. O lenei faʻamatalaga manino o le faʻamalositino o le faʻamalositino faʻatasi ma amioga faʻa-va fealoai ma le faʻafeusuaiga e maua ai se faʻataʻitaʻiga aoga mo le suʻesuʻeina o le tino o le mafaufau o le faʻalauteleina o tulaga faʻalapotopotoga i le faʻaaogaina o fualaau faasaina.
PMID: 30337639
FAIA: 10.1038/s41386-018-0235-1
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