Yana da yawancin al'aura ya rage yawan matakan testosterone?

amsa: Shawarar hujja ta nuna cewa wannan ba shi yiwuwa.

Karanta wannan labarin don taƙaitaccen bayani game da illolin haɗuwa: Maza: Shin Mawuyacin Hanyoyin Cin Hankali Ya Sa Mai Hango?

Ba abin mamaki bane cewa yawancin masu amfani da batsa waɗanda ke haifar da lalacewar maƙura suna zargin cewa al'aura ta saukar da matakan testosterone. Maza masu sanya rubutu a dandamali galibi suna faɗin abu kamar,Dukan gwaje-gwaje na gwaji sun dawo daidai, ciki har da matakan T, don haka likita ya ba ni Viagra. "

Na farko, yana da matukar wuya ED a cikin samari ya kamu da ƙananan testosterone. Abu na biyu, mutanen da ke da lalata da batsa ta ED suna bayar da rahoto game da matakan testosterone na yau da kullun, duk da haka sun kasance a fili suna aiki da yawa. Bugu da ƙari, nazarin ya ba da rahoton irin matakan testosterone a cikin maza da maza masu lafiya na kullum ED (1, 2, 3, 4). Daga waɗannan, da yawa nazarin da aka tattauna a kasa, da kuma bayanan anecdotal, za mu iya cewa:

  • low testosterone yana da wuya a cikin matasa matasa ED
  • Yawan nau'i na ejaculation ba shi da tasiri akan matakan testosterone.

A sauƙaƙe, ba mu san babu shaidar bincike ba (duk da haka) wanda ke haifar da ƙananan testosterone a cikin rahoton mummunan tasirin amfani da batsa mai yawa / al'aura. A zahiri, shaida gabaɗaya yana nuna ladaran ladaran ƙwaƙwalwar ajiya da hypothalamus a matsayin 'yan wasan tsakiya a cikin alamomin alamomin batsa, da lalata lalatawar batsa. Duba wannan bidiyo don cikakken bayani.

Wannan ba yana nufin cewa sauran canje-canjen kwakwalwa da ke haifar da batsa ba zai iya canza juzu'in hormones. Wataƙila suna yi, kamar yadda jarabawar ke canza lada, wanda na iya shafar tsarin kula da haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar haɓakar sakamako. Halin ilimin kimiyya na yanzu:

  1. Ba a "amfani da testosterone" ta hanyar inzali ko al'aura, ko da yake testosterone masu karɓa zai iya yin watsi da kwanaki 3-4 bayan ƙaddamarwa.
  2. Nazarin kan duka abstinence Kuma "haddasawa ga lalacewar jima'i”Nuna cewa ba su da wani tasiri akan matakan testosterone.
  3. A gaskiya ma, marubuta na wannan binciken da kuma wannan binciken bayar da shawarar cewa abstinence zai iya haifar da ƙarancin ƙananan matakan tustosterone.
  4. Babu daidaituwa tsakanin halayen jima'i, ko abstinence, kuma matakan testosterone plasma - ban da wani Kwana daya na tsawon lokaci (46% sama da asali) bayan kwana bakwai na abstinence. Bayan rana daya karu testosterone ya koma asali har zuwa karshen gwajin a ranar 16.
  5. Koyaya, akwai shedar cewa fitar maniyyi har zuwa satiation yana haifar da canjin kwakwalwa da yawa - gami da a raguwa a cikin masu karɓar haraji da kuma wani karuwa a cikin masu karɓar isrogen a cikin yankuna masu kwakwalwa. Saukewa daga cikewar sha'awace-sha'awace na jima'i daga 7-15 kwanakin kuma ya bambanta da canzawar kwakwalwar ƙwaƙwalwa.
  6. Lurar da aka haifar da batsa ba shi da alaƙa da matakan testosterone na jini. Shaidun da ba su dace ba, karatun ED da yawa, da ilimin kimiyyar lissafi duk sun ƙaryata wannan. Duba wannan tattaunawar ta farfesa na ilimin ilimin haihuwa - Hypogonadal maza da gyaran
  7. Babu daidaituwa tsakanin halayen jima'i, ko abstinence, kuma matakan testosterone plasma - ban da wani Kwana daya na tsawon lokaci (46% sama da asali) bayan kwana bakwai na abstinence. Mai fadi hawa da sauka a cikin matakan testosterone na maza (10-40%) na al'ada ne.
  8. Babu wata hujja game da ƙauracewa haɓaka matakan testosterone. Karatuna biyu ne kawai suka auna matakan T a yayin ƙaura na dogon lokaci - kuma dukansu basu sami canji ba:
    1.  “Mashahuri” Nazarin kasar Sin auna matakan T kowace rana don kwanaki 16, kuma ya sami ɗan ƙarami har zuwa ranar 6 - da dawowa zuwa asalin (ɗan ƙasa ƙasa) daga ranar 8 zuwa rana 16 lokacin da gwajin ya ƙare.
    2. Nazarin a #4
  9. wannan m - Endocrine amsa ga al'aura-induced orgasm a cikin maza masu lafiya bin wani 3-mako abstinence jima'i, inda batutuwa basu kwashe tsawon makonni 3 ba, galibi ana ambaton su azaman shaida cewa kamewa yana haifar da ƙara testosterone. Ba haka bane. Wannan jumla daga abin da ba a fahimta yana da ƙarancin lafazi da yaudara:kodayake plasma testosterone ba shi da kyau ta hanyar isar da kwayar cutar, an lura da yawan kwayoyin testosterone bayan lokacin abstinence“. A cikin cikakken binciken, matakan testosterone iri daya ne a cikin kungiyoyin biyu. Nemi nazarin testosterone C on shafi na 379. Lura da matakan testosterone a farkon fim (alamar minti 10) sun kasance daidai a cikin ƙungiyoyin biyu. Karshen labari. Harshen rikicewa a cikin abu mai mahimmanci yana nufin bambance-bambancen testosterone yayin al'aura. Yayin da kuke kallon fim ɗin lalata da al'aura, matakan T sun sauko don zaman al'aura na riga-kafin. Bayan kwanaki 21 na ƙauracewa, matakan T sun kasance kusa da asalin minti na 10 yayin al'aura. Sanarwar - “Yawancin kwayoyin testosterone masu tsayi sun kasance suna kiyaye bayan lokacin abstinence”- yana nufin cewa matakan testosterone ba su fadi da yawa ba yayin motsawar: taba al’aura & kallon batsa. Masu marubutan sun ba da shawarar jiran kallon batsa (wataƙila hakan ya ƙaru da hangen nesa na ƙarshe) ya sa testosterone ya kasance mai ɗaukaka a duk lokacin kallon.
  10. Nazarin Rodent a koyaushe gano cewa fitar maniyyi zuwa “shayewar sha’awa” ba shi da tasiri a matakan testosterone. Wadannan karatun suna bin dabbobi har zuwa kwanaki 15. Koyaya, suna samun canje-canje da yawa a cikin tsarin lalata, ciki har da raguwar masu karɓar nau'o'in inrogene, da haɓaka masu karɓar estrogen & opioids (wanda ke toshe dopamine), da canje-canje a cikin bayanin kwayar halitta.
  11. Dogon lokacin nazarin kan batutuwa sun nuna babu daidaitattun dangantaka tsakaninsu tsakanin kwayar halitta da matakan testosterone.
  12. By hanyar, matakan testosterone Kullum ya sauya daga 10-40%.
  13. wannan nazarin daya daga 1974 ya ba da rahoton ƙaramin aikin jima'i yana haɓaka tare da testosterone mafi girma - don wasu batutuwa, amma ba duka ba. Koyaya, binciken ya kuma gano cewa matakan testosterone mafi girma suna da alaƙa da lokacin yin jima'i. A ɗan saɓani. Bari mu sanya wannan binciken a cikin mahallin: Ba a taɓa yin ta ba kuma yana ƙunshe da ƙididdigar masu canji da ba a sarrafa su. Duk sauran nazarin dabbobi da na mutane da ke bincikar testosterone da yawan fitar maniyyi, kauracewa, matakai daban-daban na ayyukan jima'i, tare da matsalar rashin karfin jiki yana karyata bincikensa.

Kusa, amintaccen dangantaka da yanayin haɗin kai, kamar kamuwa da kanta, ƙara yawan kyakkyawan yanayin, don haka zamawa ko wasu salon al'amura na yin amfani da batsa mai tsanani zai yiwu a kashe kai tsaye daga matakan testosterone, ta hanyar epigenetics ko wasu dalilai da suke canza salon salula.

Ga wani ɓangare na musayar game da matakan testosterone da magungunan cututtukan anabolic waɗanda zasu iya zama da sha'awa ga baƙi masu haɓaka jiki. Lura: Mai amfani da cututtukan steroid zai iya zama kamu da steroid. Koda wasu experan gwaje-gwaje da beraye, waɗanda basu damu da yadda suke ba, suna nuna jaraba ga magungunan anabolic steroids. Don haka ba kawai buƙata ta hankali bane don kula da ƙwayar tsoka wacce ke sanya masu amfani. Babban matakan har ila yau, hana ingancin testosterone naka. Yi hankali.

  • tambaya: Tun yaushe ka hau HRT? Akwai tarin adabin adabi wanda ke nuni da cewa karancin testosterone yana haifar da canje-canje a cikin tsarin kayan halittar mazakuta, wanda ke haifar da matsalar rashin kuzari. Idan testosterone ya tabbatar da rauni, wannan shine wataƙila dalilin matsalolinku na yanzu. An yi sa'a, an nuna cewa waɗannan canje-canje a cikin kayan ƙwanƙwasa suna da yawa ana juyawa tare da HRT. Zai zama mai kyau a tsammanin zai ɗauki ɗan lokaci kaɗan don ayyukanku don haɓaka fiye da yadda zai ɗauka don testosterone su isa matakan al'ada, tunda wannan shine ainihin canjin jiki a cikin tsoka mai santsi, ba abu mai sauƙi na matakan hormone ba. Saboda son sani, shin zan iya tambayar shekarunku, tsawon lokacin da kuka kasance kuna fuskantar matsaloli na tashin hankali, da kuma tsawon lokacin da kuka yi aikin likita har yanzu?
  • amsa: Ina kan HRT yanzu na shekaru 2. Shekaruna 40 yanzu. Na kasance ɗan wasan kusa da na ƙuruciya mai ƙarfi na tsawon shekaru 20. A wannan lokacin na yawaita amfani da magungunan asrogen (AAS). Wannan shine dalilin da yasa testosterone na ya ragu lokacin da na daina amfani da AAS 3 shekaru da suka gabata. Bayan shekara guda na murmurewa matakan testosterone na marasa ƙarfi har yanzu basu kasance ba, don haka ne lokacin da na tafi HRT. Shekaru 8 da suka gabata, ingancin kayan aikin da nake yi bai da kyau. Don haka, wannan lokacin ne lokacin da nake kan AAS da kashe shi da kuma lokacin HRT kuma. Akwai dalilai da yawa da suka shafi cewa yana da wuya a faɗi abin da ke haifar da ED na. Ina fatan sake sakewa zai iya taimaka min game da wannan matsalar. A yanzu haka ban san wasu hanyoyin da nake da su ba.

Sakamakon rashin aiki na jima'i a cikin raguwa mai sauƙi na LH bioavailability.

Int J Matsarar Res. 2002 Apr; 14 (2): 93-9; tattaunawa 100.

Carosa E, Benvenga S, Trimarchi F, Lenzi A, Pepe M, Simonelli C, Jannini EA.

Abstract

Mun rubuta kwanan nan da muhimmanci rage kwayoyin testosterone (T) a cikin marasa lafiya da ciwon daji (ED). Don fahimtar ma'anar wannan hypotestosteronemia, wadda ta kasance mai zaman kanta ta ilimin halitta na ED, da kuma ƙarfinsa kawai a cikin marasa lafiya wanda wasu maganin da ba a taba amfani da shi ba sun dawo da aikin jima'i, mun auna kwayar cutar hormone (LH) a cikin tsararrakin na marasa lafiya na ED ( n = 83; 70% kwayoyin halitta, 30% nonorganic). Dukkanin LH (I-LH) da bazuwa da kwayoyin halitta (L-LH) ne aka auna su a shiga da kuma watanni 3 bayan farfadowa. Bisa ga sakamakon (watau yawan yunkurin yin jima'i da wata), marasa lafiya sun rarraba a matsayin cikakken masu amsawa (watau akalla ƙoƙari guda takwas; n = 51), masu amsawa na kai tsaye (akalla ƙoƙari guda ɗaya; n = 20) da wadanda basu amsawa ba (n = 16). Idan aka kwatanta da 30 masu lafiya ba tare da ED ba, asalin B-LH (yana nufin +/-sd) a cikin marasa lafiya 83 ya ragu (13.6 +/- 5.5 vs 31.7 +/- 6.9 IU / L, P <0.001), ta fuskar kadan ya karu, amma a cikin zangon al'ada, I-LH (5.3 +/- 1.8 vs 3.4 +/- 0.9 IU / L, P <0.001); saboda haka, an rage ragamar B / I LH (3.6 +/- 3.9 vs 9.7 +/- 3.3, P <0.001). Hakazalika da lura da mu na baya ga magani T, ƙungiyoyi uku waɗanda suka fito ba su bambanta da muhimmanci ga kowane ɗayan waɗannan sigogi uku ba. Duk da haka, ƙungiyoyi masu jituwa sun bambanta bayan farfadowa. Haɓakawar LH ya karu a cikin cikakken masu amsawa (pre-therapy=13.7+/-5.3, post-therapy=22.6+/-5.4, P<0.001), a hankali a cikin masu saurare (14.8 +/- 6.9 da 17.2 +/- 7.0, P <0.05) amma ya kasance ba canzawa a cikin wadanda basu amsa ba (11.2 +/- 2.2 vs 12.2 +/- 5.1). Canje-canjen da suka yi daidai sun tafi ta kishiyar I-LH (5.2 +/- 1.7 vs 2.6 +/- 5.4, P <0.001; 5.4 +/- 2.2 vs 4.0 +/- 1.7, P <0.05; 5.6 +/- 1.2 vs 5.0 +/- 1.2, bi da bi), kuma a daidai wannan hanya kamar B-LH don ƙimar B / I (3.7 +/- 4.1 vs 11.8 +/- 7.8, P <0.001; 4.2 +/- 4.3 vs 5.8+ /-4.2, P <0.05; 2.1 +/- 0.7 vs 2.6 +/- 1.3, bi da bi). Muna tsammanin cewa hypotestosteronemia na marasa lafiya na ED ne saboda rashin lalatawar LH. Wannan rage yawan haɓakaccen abu ne mai juyayi, idan har an sake dawowa da jima'i ba tare da la'akari da ka'idar magani ba. Saboda yawan kwayar halittar hormones da ake sarrafawa ta hypothalamus, LH hypoactivity ya kamata ya kasance saboda lalacewar aiki na hypothalamic da ke haɗuwa da rikice-rikice na rashin hankali wanda ba zato ba tsammani bi rashin aiki na jima'i.

ABUBUWAN: Mawallafa sun bada shawara cewa yin jima'i yana ƙaruwa da LH da testosterone a cikin maza suna tafiya don ED. Babu wani namiji da tayi da aka yi masa da hormones, kuma low testosterone ba shine dalilin ED ba. Idan gaskiya a cikin mazaunin lafiya, wannan yana nuna cewa jima'i / jigilar kwayar halitta na iya hana rikici a matakan testoterone.

HANYAR DA KARANTA DA KUMA DA KUMA DA KUMA KUMA KUMA GASKIYA DA KARANTA DUNIYA

Scand J Psychol. 2003 Jul;44(3):257-63.

Fernández-Guasti A, Rodríguez-Manzo G.

Abstract

Wannan labarin yana duba abubuwan da ke faruwa a yanzu game da abubuwan da ke sha'awa game da jima'i. Knut Larsson a cikin 1956 ya ruwaito akan ci gaba da ciwon jima'i a cikin namijin namiji bayan sakewa. Munyi nazarin tsari kuma muka sami sakamakon da ya biyo baya.

(1) Wata rana bayan 4 hours na ad libitum copulation, kashi biyu bisa uku na yawan nuna nuna cikas ga halin jima'i, yayin da sauran na uku ya nuna wani tsari na yau da kullum wanda ba su warkewa ba.

(2) Magungunan maganin magunguna, ciki har da 8-OH-DPAT, yohimbine, naloxone da naltrexone, sun juya wannan jima'i ta hanyar nuna jima'i, yana nuna cewa tsarin baradrenergic, serotonergic da opiate suna cikin wannan tsari. Lalle ne, ƙayyadaddun ƙananan neurochemicals sun nuna canje-canje a cikin wasu maɓuɓɓugar da ke tattare da su a lokacin da ake cin zarafin jima'i.

(3) An ba da ƙarfin da ya dace, ta hanyar canza mace mai tasowa, an dakatar da jin daɗin jima'i, yana nuna cewa akwai wasu abubuwan da ke motsawa game da lalata jima'i da ke nuna rashin cin zarafin jima'i..

(4) Gaddafi na GABA bicuculline, ko motsi na lantarki na yankin da ke tsakiyar, ba ya canza karfin jima'i. Wadannan bayanai sun nuna, a gefe guda, cewa rushewar jima'i da kuma lokacin da aka ƙaddamar da shi (wanda aka rage ta hanyar bicuculline administration) ba a daidaita shi ta hanyar irin wannan tsarin ba, kuma, a daya bangaren, cewa yankin preoptic ba ya tsara tsarin jin dadi.

(5) Maganin karɓan inrogene a cikin sassan kwakwalwan da ke da alaƙa da magana akan halin jima'i na namiji, irin su tsakiya na farko, wanda aka ragu sosai a cikin dabbobi marasa ƙarfi. Irin wannan raguwa ya ƙayyade ga wasu ƙwayoyin kwakwalwa kuma ba shi da dangantaka da canje-canje a cikin matakan androgens. Wadannan sakamakon suna nuna cewa canje-canjen a cikin asusun masu karɓar nauyin kwakwalwa na kwakwalwa don magance halin jima'i da ke cikin lokacin cin zarafin jima'i.

(6) Hanyar dawo da jima'i bayan 4 hours na ad libitum copulation ya nuna cewa, bayan 4 kwanakin, kawai 63% na maza za su iya nuna halin jima'i bayan bayan 7 days duk dabbobin nuna aikin kwakwalwa.

ABUBUWAN: Yankin kwakwalwa inda inda aka sauke mai karɓa ya zama kamar kamanni a cikin dukan dabbobi. Idan wannan saukewa a cikin masu sauraron testosterone ya auku a cikin maza, zai iya bayyana dalilin da yasa wasu mutane ke jin kamar su testosterone ba su da kyau bayan cin zarafi mai yawa, kuma me yasa suke jin kamar matakan testosterone sun tashi tare da lokacin abstinence.

NOTE: Wannan sakamako na wucin gadi ana aunawa a cikin kwakwalwar al'ada. Idan kwakwalwarka ta canza saboda jaraba, zabin dopamine yana dysregulated, ba tare da jinkirin jinkiri na masu karɓa na testosterone ba, kuma zaka bukaci ya fi tsayi don komawa libido.

Hakanan: # 4 - An hana gajiyar jima'i ta hanyar gabatar da wata budurwa (wannan shine abin da batsa yake yi).

Ƙara yawan haɗin gwargwadon ciwon isrogen receptor alpha a cikin kwanan baya na ratsan jima'i.

Horm Behav. 2007 Mar; 51 (3): 328-34. Epub 2007 Jan 19.

Phillips-Farfán BV, Lemus AE, Fernández-Guasti A.

Abstract

Hajjin mai karɓar isrogen din (ERalpha) yana cikin ka'idojin neuroendocrine na halin jima'i na namiji, musamman a wuraren kwakwalwa da ke cikin tsarin lalata. Maza da yawa daga cikin jinsunan suna gabatar da jima'i a lokacin da aka yi jima'i da yawa, wanda aka sani da jin dadi. An nuna cewa yawan karuwar mai karɓar nau'in hawan mai karu da aka rage 24 h bayan bayanan guda ɗaya ko mating to satiety, a cikin yankin preoptic na tsakiya, ƙananan haɓaka da ƙwararrun hypothalamus. Manufar wannan binciken shine yayi nazari idan yawancin na ERalpha ya sake canza 24 h bayan bayanan jima'i ko mating to satiety. Jima'i da jima'i an hade shi tare da kara yawan ƙwayar ERALAP a cikin litattafan gado mai kwakwalwa na stria terminalis (BSTMA), septum (ventilateral septum (LSV), postrodorsal medial amygdala (MePD), yankin preoptic medial (MPA) da nucleus accumbens core (NAc). Hoto guda ya danganci karuwa a ma'auni na ERALAP a cikin BSTMA da MePD. Ƙananan ƙananan ƙwayoyin cuta a arc (Arc) da kuma watau hypothalamic ventromedial (VMN), kuma matakan yadurol zazzabi sun kasance ba su canzawa ba 24 h bayan bayanan daya ko mating to satiety. Wadannan bayanan suna ba da shawara akan dangantaka tsakanin jima'i da kuma karuwa a fadin ERALAP a yankunan ƙwararrun ƙwayoyin cuta, ba tare da matakan estradiol ba a cikin tsarin jiki..

HALITTA: Ƙwararrun masu karɓar karuwar jinin karuwa yana ƙaruwa a yankunan da dama bayan ango guda, da kuma jima'i. A cikin cikakken nazarin suna cewa wannan canjin yana da tsawo fiye da 24 hrs.