ʻOkakopa 19, 2014 ma Psychology & Psychiatry /
He olima maoli ka lolo i nā kānaka āpau. I kēia manawa noiʻi hou, i hōʻike ʻia ma ka ECNP Congress ma Berlin, ua ʻike ua ʻokoʻa ka ʻōnaehana opioid o nā poʻe pāʻani o ka pathological ʻokoʻa i pane aku i nā mea hana olakino maʻamau. Ua hana ʻia e ka hui o nā mea noiʻi o UK mai Ladana a me Cambridge, a ua hoʻokumu ʻia ʻo ia e ka Medical Research Council. Hana ʻia kēia hana ma ka hale kula o European College of Neuropsychopharmacology ma Berlin.
ʻO ka pāʻani petele he ʻano pālahalaha nui e pili ana iā 70% o ka poʻe Pelekane ma ka piliona i kekahi manawa. Eia nō naʻe, i kekahi o nā poʻe, e hoʻowalewale nā kaila hoʻāla a lawe i nā hiʻohiʻona o kahi hoʻohui - ka pāʻani pila, ʻike ʻia i ka pāʻani pili pilikia. Ua manaʻo ka 2007 Pelekane Pelekikena Prevalence Survey1 aia ka 0.6% o UK he pākē he pilikia me ka pili ʻana, ua like me ka 300,000 poʻe, kahi e puni ana i ka heluna holoʻokoʻa o kahi kūlanakauhale e like me Swansea. Loaʻa kēia kūlana i ka laha o 0.5 − 3% ma ʻEulopa.
Ua lawe aku ka poʻe noiʻi i ka poʻe gambler 14 pathological a me 15 mau mea ola olakino, a ua hoʻohana i nā pēpē PET (nā kākena Positron Emission Tomography) e ana i ka pae o ka opioid receptor i loko o kaole o nā hui ʻelua. Ke ʻae nei kēia mau ʻale i ka kelepona i ke kamaʻilio kelepona - like lākou me ka laka me ka neurotransmitter a i ʻole kemana, e like me ka endogenous opioids i kapa ʻia ʻo endorphins, e hana ana me ke kī. Ua ʻike nā mea noiʻi, ʻaʻohe ʻano ʻokoʻa ma waena o nā pae receptor i nā mea hele aku a me nā mea ʻike ʻole. He ʻokoʻa kēia i ka hāʻawi ʻana i ka waiʻona, heroin a i ʻole ka cocaine i ʻike ʻia ai nā hoʻonui e opioid receptor.
Hāʻawi ʻia nā kumuhana āpau i kahi papa amphetamine e hoʻokuʻu ana i ka endorphins, he mau opiates maoli, i loko o ka lolo a haʻi hou i ka scan PET. ʻO kēlā hoʻokuʻu - i kapa ʻia ʻo 'endorphin rush'- manaʻo pū ʻia kekahi me ka wai ʻona a me ka hoʻoikaika kino. Ua hōʻike ka scan PET i ka hoʻokuʻu ʻana o nā mea pāʻani pathological i nā endorphins liʻiliʻi ma mua o nā mea manawaleʻa piliwaiwai ʻole a pili pū ʻia me ka amphetamine e hoʻoulu ana i ka euphoria e like me ka mea i hōʻike ʻia e nā mea manawaleʻa (e hoʻohana ana i kahi nīnau nīnau helu ponoʻī i kapa ʻia ʻo 'Mana maʻalahi o ka helu nīnau ninaninau amphetamine. pālākiō ', a i ʻole SAIRS).
ʻO ke alakaʻi ma ka mea noiʻi Dr Inge Mick i ʻōlelo:
"Mai kā mākou hana, hiki iā mākou ke ʻōlelo i nā mea ʻelua. ʻO ka mea mua, pane ʻokoʻa ka lolo o nā mea pāʻani pathological i kēia stimulate ma mua o ka lolo o nā mea manawaleʻa olakino. A ʻo ka lua, me he mea lā ʻaʻole e like ka manaʻo o ka euphoria me nā mea manawaleʻa olakino. Hele paha kēia i kekahi ala e wehewehe ai i ke kumu e lilo ai ka piliwaiwai i mea hōʻalo ”.
"ʻO kēia ke aʻo kiʻi PET mua e nānā i ke komo ʻana o ka ʻōnaehana opioid i ka piliwaiwai pathological, kahi ʻano lawehala. Ke nānā nei mākou i ka hana ma mua i nā hana ʻona ʻē aʻe, e like me ka wai ʻona, manaʻo mākou e hoʻonui ka poʻe piliwaiwai pathological i nā mea loaʻa i ka opiate i loaʻa ʻole iā mākou, akā ua ʻike mākou i ka loli ʻana o ka opioids endogenous mai kahi pilikia amphetamine. Hōʻike kēia mau hopena i ke komo ʻana o ka ʻōnaehana opioid i ka piliwaiwai pathological a ʻokoʻa paha ia mai ka hoʻāʻo ʻana i nā mea e like me ka waiʻona. Lana ko mākou manaʻo i ka holo lōʻihi hiki ke kōkua iā mākou e hoʻomohala i nā ala hou e mālama ai i ka piliwaiwai pathological ”
E kamaʻilio no ka inoa o ka ECNP, Ua'ōlelo ʻo Wim van den Brink (Amsterdam), ka luna o ke komite ʻepekema no ka ʻAha ʻona ʻo Berlin.
"I kēia manawa, ʻike mākou i ka hoʻomaʻamaʻa me nā antagonists opioid e like me naltrexone a me nalmefene me he mea lā he hopena maikaʻi i ka mālama ʻana i nā pathological piliwaiwai, a ʻo nā hopena maikaʻi loa o kēia mau lāʻau i loaʻa i kēlā mau mea piliwaiwai pilikia me kahi moʻolelo ʻohana o ka hilinaʻi ʻalekohola. Akā ʻo kēia hōʻike mai Dr Mick a me nā hoa hana he hana hoihoi ia, a inā i hoʻokūpaʻa ʻia hiki iā ia ke wehe i nā puka i nā ʻano lapaʻau hou no nā mea pāʻani pathological ”.
Hāʻawi ʻia e European College of Neuropsychopharmacology
"Pili ka piliwaiwai pilikino me ka ʻōnaehana opioid i hoʻololi ʻia i ka lolo." ʻOkakopa 19, 2014. http://medicalxpress.com/news/2014-10-pathological-gambling-opioid-brain.html
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