Addict Behav. 2018 Oct 16; 90: 62-70. hana: 10.1016 / j.addbeh.2018.10.019.
Wang M1, Zheng H1, Du X2, Dong G3.
Hōʻuluʻulu Manaʻo
KOKO:
ʻO ka hoʻomaopopo ʻana i ke kumu neural e pili ana i ka maʻi pilalelo Pūnaewele (IGD) pono no ka maʻi a me ka mālama ʻana i kēia ʻano o ka hoʻohui ʻana i ka ʻano. Ua hōʻike ʻia kahi kūlana hoʻomaha hoʻomaha kūlana aupuni (rsFC) o ke kikowaena mode default (DMN) i loko o nā mea pilikino me IGD. No ka mea, ʻaʻole he palapala kuhikuhi ʻo rsFC, ka pilina kūpono ma waena o DMN i IGD. Maanei, ua hana mākou i ka hoʻohālike modelalization kumu kumu nui (spDCM) e makaʻala i kēia pilikia.
KANAKA:
I hōʻiliʻili ʻia ka ʻikepili o ka fMRI mokuʻāina mai 64 IGD (makahiki: 22.6 ± 2.2) a me 63 ka hoʻohana ʻana i nā mea pāʻani leʻaleʻa launa pūnaewele maikaʻi (RGU, makahiki: 23.1 ± 2.5). ʻO ka huaʻōlelo manawa nui ma Voxel i hoʻokumu ʻia mai nā ʻāpana ʻaha 4 i loko o ka DMN (medial prefrontal cortex, mPFC; posterior cingulate cortex, PCC; bilateral inferior parietal lobule, waiho IPL / pololei IPL) o nā hui ʻelua i ka wā hoʻomaha. ka helu spDCM.
Nā hopena:
Hoʻohālikelike ʻia me RGU, hōʻike ʻo IGD i ka hoʻohaʻahaʻa maikaʻi ʻana i ka hoʻohui mai ka mPFC a i ka PCC a mai ka IPL hema a i ka mPFC, me ka hoʻoliʻi pili pono ʻana i ka PCC a me ka IPL hema.
NĀ KUMU:
Hiki i ka spDCM ke hoʻokaʻawale i nā loli i ka papa hana hana ma waena o nā hui ʻelua i ʻoi aku ma mua o ka rsFC. Hōʻike ʻia kā mākou mau ʻike i ka hoʻohaʻahaʻaʻana i ka hoʻokaʻawaleʻana o ka excitatory mai ka mPFC a i ka PCC paha he mea nui nui ka biomarker no IGD. Pono ka wawaʻi ʻana o ka lolo i ka manawa e nānā pono ai i ka lohi ʻana i nā pōpilikia IPL-mPFC-PCC.
KEYWORDS: Pūnaewele kūpono ʻole; Hoʻohui maikaʻi; Pūnaewele ʻO ka pāʻani pūnaewele; Cortex medial prefrontal; Spectral hoʻololi kumu kumu kumu
PMID: 30366150
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