ʻO Medicine (Baltimore). 2017 Sep; 96 (36): e7995. doi: 10.1097 / MD.0000000000007995.
Kēlā M1, Kim YJ, Kim DJ, Choi JS.
Hōʻuluʻulu Manaʻo
ʻO ka maʻi ma ka pāʻani pūnaewele (IGD), i ho'ākāka ʻia me ka hiki ʻole ke hoʻokele i ka pāʻani pāʻani ʻana i ka Pūnaewele, alakaʻi i ka hōʻeha nui i ka noʻonoʻo a me ka hana lima, akā he liʻiliʻi nā noiʻi ua ʻike i nā ʻano neurophysiological o nā maʻi me ka IGD. ʻO ka pahuhopu o kēia noiʻi e hoʻoholo ʻia nā hōʻailona o ka neurophysiological o nā māhele P300 e pili ana i nā loli i nā hōʻailona ma hope o ka hoʻokele outpatient me ka pharmacotherapy i nā poʻe maʻi me ka IGD. Ua aʻo ʻia kēia mau haʻawina lōʻihi lōʻihi me 18 me nā mea maʻi XDUM a me 29 mau olakino olakino. ʻO ka poʻe maʻi me IGD i hoʻopau i kahi papahana hoʻokele outpatient mahina 6 e komo pū me kahi serotonin reuptake inhibitor-based pharmacotherapy. Loaʻa nā mea i pili i ka hanana (ERP) i ka wā auditory oddball hana. Hoʻokomo ʻia nā ERP o nā mea maʻi me ka IGD ma mua a ma hope o ka mālama ʻana. Ma waena o nā ʻokoʻa i waena o ka pūʻulu a me ka hoʻololi mua o ka mālama ʻana i nā ʻina mua ma ka P300 i hōʻike ʻia me ka hoʻohuli ʻana i nā helu ʻano like ʻole like ʻole. ʻO ka hopena hopena mua ka hoʻololi ʻana ma ka helu ma ka Hoʻohālikelike ʻana i ka Pūnaewele Pūnaewele ma waena ma mua a ma hope o ka mālama ʻana. Ma nā loiloi pae kahua, hōʻike ka pūʻulu IGD i ka hoʻohaʻahaʻa nui ʻana i nā kiʻekiʻena P300 a ua hoʻopuhi ka lōʻihi ma ka pae waena o centro-parietal pūnaewele i hoʻohālikelike ʻia me ka poʻe i loko o nā pūnaehana olakino. ʻAʻole i loli nui i nā ʻōkuhi P300 i nānā ma waena o ka mua a me ka mālama ma hope o ka mālamaʻana i ka poʻe maʻi me ka IGD ma hope o ko 6 mau mahina o ka mālama ʻana, ʻoiai nā mea maʻi me IGD e hōʻike i nā hoʻomaikaʻi nui i ko lākou mau hōʻailona IGD. Eia kekahi, ʻaʻohe ʻike nui i ka ERP i nānā ma waena o nā mea pane a me nā mea ʻole i mālama i kahi mālama mālama 6-malama i nā maʻi me ka IGD. Hōʻike kēia mau hopena i ka hōʻemi nui o nā P300 a me nā lohi ka lōʻihi he mau endophenotypes poʻomanaʻo ma ka pathophysiology o IGD.
PMID: 28885359
DOI: 10.1097 / MD.0000000000007995
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