ʻO Jokinen, ʻo Jussi
ʻO Umeå University, Faculty of Medicine, Keʻena ʻOihana ʻepekema Hema.ORCID iD: 0000-0001-6766-7983
Flanagan, Ioane
ʻO Chatzittofis, Andreas
ʻO Umeå University, Faculty of Medicine, Keʻepekema o Kālepekema Kūlana.
ʻO Öberg, Katarina
ʻĀkaukau [en]
Ka Ike: ʻO ka maʻi hypersexual (HD) e hoʻopili nei i nā ʻano pathophysiological e like me ka deregulation makemake i ka moekolohe, ka moekolohe, ka impulsivity a me ka compulsivity i hōʻike ʻia ma ke ʻano he diagnostic no ka DSM-5. Hōʻike ʻia ʻo "Compulsive Sexual Behaviour Disorder" i kēia manawa ma ke ʻano he mana hoʻomalu impulse i ICD-11. Hōʻike nā noiʻi hou i ka axis HPA disregulated i nā kāne me HD. Hoʻopili ka Oxytocin (OXT) i ka hana o ka axis HPA; ʻaʻohe noiʻi i loiloi i nā pae OXT i nā mea maʻi me HD. Inā paha he hopena ka CBT no nā hōʻailona HD ma nā pae OXT ʻaʻole i noiʻi ʻia.
Nā Palapala: Ua nānā mākou i nā pae o ka OXT plasma i 64 nā maʻi kāne kāne me ka HD a me nā mea hana ʻelemakule olakino ʻelima kāne ʻelima. Eia kekahi, ua nānā mākou i nā loulou ma waena o nā pae wai o OXT a me nā hōʻailona o ka HD me ka helu ʻana i nā pae helu helu e ana ana i nā ʻano hypersexual: Hypersexual disorder screening inventory (HDSI) a me ka Sexual Compulsive scale (SCS). ʻO kahi mahele o nā mea maʻi (N = 38) i hoʻopau ʻia i ka papahana CBT-lawelawe lawelawe hoʻonaʻauao maʻamau no HD a loaʻa kahi helu lua o ka OXT ma ka hana ma hope o ka mālama. Ua nānā ʻia ʻo OXT me Radioimmunoassay (RIA).
Nā Hualoaʻa: ʻO nā mea maʻi me HD i ʻoi aku ka nui o ka kiʻekiʻe OXT (mean 31.0 ± SD 9.9 pM) i hoʻohālikelike ʻia me nā mea manawaleʻa olakino (mean 16.9 ± SD 3.9 pM) (p <0.001). Aia kekahi mau pilina maikaʻi maikaʻi ma waena o nā pae OXT a me nā unahi hoʻohālikelike e ana ana i ka hana moekolohe (Spearman rhos ma waena o HDSI r = 0.649, p <0.001 a me SCS r = 0.629, p <0.001) i hui pū ʻia me nā haumāna. ʻO nā mea maʻi i hoʻopau i ka hoʻoponopono CBT i hoʻoliʻiliʻi nui o nā pae OXT mai ka mālama mua ʻana (30.5 ± 10.1pM) i ka lāʻau lapaʻau (20.2 ± 8.0pM) (p <0.001). ʻO nā mea maʻi me HD i ka hoʻopili maikaʻi maikaʻi o kā lākou hoʻololi i HD: CAS me ka pae oxytocin plasma ma mua a ma hope o CBT (r = 0.388, p waiwai = 0.0344).
Nā hopena. Hiki i ka ʻōnaehana hui CBT holomua ke hopena i ka ʻōnaehana ʻo ka maʻi hyperactiveergic.
Wahi, mea hoʻopuka, makahiki, paʻi, ʻaoʻao
Mālama Hoʻolauna Kūlohelohe, 2019. Vol. 44, p. 114-114
Huaʻōlelo [en]
ʻO Oxytocin a me ka Hoʻomaka, Hypersexual Disorder, Cognitive Behavi Therapy
ʻĀpana Lahui
Pharmacology a me Toxicology Neurosciences Psychiatry
Nā mea ʻike
URN: urn: nbn: se: umu: diva-168967ISI: 000509665600228OAI: oai: DiVA.org: umu-168967DiVA, id: diva2: 1420877
hālāwai
He hālāwai ʻaha kūloʻo 58 o ka American-College-of-Neuropsychopharmacology (ACNP), DEC 08-11, 2019, Orlando, FL
Ke hoʻohui: 1
Hui Hoʻomaka: M71
Loaʻa mai: 2020-04-01 Ua hana ʻia: 2020-04-01 Hoʻohou hou: 2020-04-01
;