ʻO ka pane kūpono ʻana e pili ana i ka hoʻohaʻahaʻa kūpono i ka Transcranial Magnetic Stimulation (2020)

He hana hōʻemi ka hana hoʻokalakupua (CSB) he pilikia hoʻopiʻi, ka hopena o ka hōʻino ʻana o ka psychosocial, ʻoihana kālā a me nā pilikia o ka ʻohana, a me nā kiʻekiʻe kiʻekiʻe o nā maʻi o ka moekolohe. Loaʻa i nā hanana i kēia manawa no ka CSB kahi hōʻike hōʻike ikaika a paʻakikī hoʻi i nā hihia he mea paʻakikī ke hele.1 ʻOiai ʻaʻole i ʻike ʻia i nā hoʻokolohua nui, hiki i ka transcranial magnetic stimulation (TMS) ke hoʻolako i kahi mālama kūpono no CSB. Eia kekahi, ma ke koho pono ʻana i nā pōloli neural kikoʻī, hiki i ka TMS ke hāʻawi i nā ʻike koʻikoʻi e pili ana i nā ʻāpana o ka lolo i hoʻopili ʻia i ka pathophysiology o nā ʻano lawelika pilikia. Ke hōʻike nei mākou ma kahi hihia o CSB nāna i pane mai i ka TMS hohonu o ka cortex ana mua.

Kūkākākā

He kāne ʻo 34 i ka makahiki XNUMX me CSB a hui pū ʻia me ka maʻi kūwaho (OCD). Ua hōʻike ʻia kāna CSB me ka hoʻohana nui ʻana i ka pona a me ka hana hoʻomālamalama, a me ka hopena o ka nui o ka hana o ka hana. Ua hōʻoia ʻia ka hopena maʻi ʻo CSB me ka ninaninau o nā ʻĀina ʻorderslelo Hoʻoikaika Minnesota Impulse.2 Ma mua o ka loaʻa ʻana o ka TMS, ʻike ʻia ka ʻike ʻo Mr A ma ka Yale-Brown Obsitive-Compulsive Scale i hoʻonohonoho ʻia no CSB (CSB-YBOCS)3 he 23, kūlike me ka maʻi ʻehaʻeha. Ua mālama ʻia ʻo ia me kahi maʻi mau o ka fluoxetine (40 mg i kēlā me kēia lā) no OCD me ka hoʻomaha iki mai kona CSB a i ʻole OCD. ʻAʻole loli i ka wai lapaʻau lāʻau i ka wā mālama.

Ma hope o ka hāʻawi ʻana i ka ʻae hoʻomaopopo, ua hōʻea ʻo Mr A i ka nui o 28 mau papa o ka TMS hohonu (ma mua o 6 mau hebedoma) e kuhikuhi ana i ka anterior cingulate cortex (ACC) e hoʻohana ana i kahi ala ʻo Brainsway Deep TMS i lako me ka H7-coil (Brainsway Ltd, Tel-Aviv, Israel ). Ua hōʻike ʻo Mr A i kahi hoʻohaʻahaʻa 39% i nā hōʻailona o ka CSB ma luna o 6 mau pule (ʻo kāna kiʻi posttreatment CSB-YBOCS he 14, ka mea like me ka maʻi maʻi). Hoʻomaikaʻi hou ʻia kona mau ʻōhua OCD holoʻokoʻa mai ka pae lalo ma hope o TMS (pretreatment YBOCS score = 35, posttreatment YBOCS score = 13). Ua makapō ʻo M. A a me nā mea loiloi i ka hoʻomaʻamaʻa ʻana ʻo ia i ka lawena. Ua hōʻike ʻo ia i nā hopena pili i pili i ka mālama ʻana. Ua apono ʻia nā kaʻina hana āpau e kahi papa kūkā o ka hui.

kūkākūkā

Ke hōʻike nei kēia hihia i nā hohonu hohonu e nānā ana i ka ACC e lilo paha i hana kūpono no CSB. Ua kūpono kēia ʻike i ka noiʻi neuroimaging hana i hoʻokomo ai i ka ACC ma CSB ma ka hōʻike ʻana ua hōʻike nā kāne me CSB i ka nui o ka hana ma ACC e pane ana i nā kikoʻī pilikino (ʻo ia hoʻi, nā kiʻi porno) ma mua o nā kāne me ka ʻole o CSB.4 Aia paha he hiki ke hoʻomohala nui nā TMS o ka ACC i nā hoʻololi kūlohelohe i nā wahi neural e pili pū me ka ACC. ʻOiai e mau ʻole nā ​​ʻenekini pae pae ʻai, ʻike kēia mau ʻike i ka TMS hohonu e hōʻike i kahi koho koho no ka CSB. Hōʻike ka hoʻomaikaʻi ʻana i kēia mea maʻi i ka hoʻoponopono ʻana i nā loli o ka maʻi OCD. Pono ke noiʻi hou e hōʻoia i kēia mau ʻike a ʻike i kā lākou kumu kūlohelohe.

E hoʻomaopopo '

1. Derbyshire KL, Grant JE. ʻO ke ʻano hana hoʻohālikelike: ka nānā ʻana i ka palapala. ʻO J Behav Addict. 2015;4(2):37–43. HoʻokuʻuʻiaKeoki Hōʻike Abstract
2. Hāʻawi iā JE. Hōʻehaʻeha Kūʻē Manaʻi: ʻO ke alakaʻi a kahi kauka i ka hoʻomaopopo ʻana a me ka mālama ʻana i nā hōʻiliʻili maikaʻi. ^ E Ha yM. Nuuka, NY: WW Norton; 2008.
3. Kraus SW, Potenza MN, Martino S, et al. Ke nānā nei i ka waiwai psychometric o ka Yale-Brown Obsessive-Compulsive Scale i kahi hoʻohālike o nā mea hoʻohana hoʻomehana hoʻomālamalama. Pūʻulu Pūʻali. 2015; 59: 117-122. HoʻokuʻuʻiaKeoki Hōʻike Abstract
4. Voon V, Mole TB, Banca P, et al. ʻO ka neural correlates e pili ana i ka cue moekolohe i loko o nā poʻe me ka ʻole o ka hoʻonaninani. PLoS One. 2014; 9 (7): e102419. HoʻokuʻuʻiaKeoki Hōʻike Abstract