Brain correlates of response inhibition in Internet gaming disorder (2014)

Psychiatry Clin Neurosci. 2014 Jul 22. doi: 10.1111/pcn.12224.

Chen CY1, Huang MF, Yen JY, Chen CS, Liu GC, Yen CF, Ko CH.



The present study aimed to evaluate the brain correlates of response inhibition among subjects with internet gaming disorder (IGD).


For this purpose, 15 men with IGD for at least 1 year, and 15 controls with no history of IGD were recruited to perform the Go/Nogo task under functional magnetic resonance imaging (fMRI) investigation. Prior to scanning, the subjects were assessed using the Chen Internet Addiction Scale and the Barrett Impulsivity Scale.


The control group exhibited activation of the right supplement motor area, dorsolateral prefrontal cortex, and caudate for response inhibition. However, the IGD group had a higher impulsivity and lower activity of the right supplement motor area (SMA)/preSMA in comparison to the control group.


The results obtained ssuggest that dysfunctional activation of the supplement motor area for response inhibition is one of the candidate mechanisms of IGD.

This article is protected by copyright. All rights reserved.


Internet gaming disorder; impulsivity; response inhibition; supplement motor area