Brain correlates of response inhibition in Internet gaming disorder (2014)

Psychiatry Clin Neurosci. 2014 Jul 22. doi: 10.1111/pcn.12224.

Chen CY1, Huang MF, Yen JY, Chen CS, Liu GC, Yen CF, Ko CH.

Abstract

AIM:

The present study aimed to evaluate the brain correlates of response inhibition among subjects with internet gaming disorder (IGD).

METHODS:

For this purpose, 15 men with IGD for at least 1 year, and 15 controls with no history of IGD were recruited to perform the Go/Nogo task under functional magnetic resonance imaging (fMRI) investigation. Prior to scanning, the subjects were assessed using the Chen Internet Addiction Scale and the Barrett Impulsivity Scale.

RESULTS:

The control group exhibited activation of the right supplement motor area, dorsolateral prefrontal cortex, and caudate for response inhibition. However, the IGD group had a higher impulsivity and lower activity of the right supplement motor area (SMA)/preSMA in comparison to the control group.

CONCLUSION:

The results obtained ssuggest that dysfunctional activation of the supplement motor area for response inhibition is one of the candidate mechanisms of IGD.

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KEYWORDS:

Internet gaming disorder; impulsivity; response inhibition; supplement motor area