This section deals with the research about sensitization. Sensitization is the increase in sensitivity to a drug or natural reward after continued use. Sensitization is a manifestation of neuroplastic changes in response to repeated exposure, and some researchers have hypothesized that it is a behavioral correlate of increased craving and development of dependence. Put simply: continued use creates powerful, motivating memories related to one’s addiction. When activated by cues these memories stir cravings while increasing dopamine. Sensitized pathways remain long after the addict quits using.
Sensitization Research
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