Front Behav Neurosci. 2014; 8: 117. Published online 2014 Apr 3. doi: 10.3389/fnbeh.2014.00117 PMCID: PMC3982054 Alessandra Matzeu,* Eva R. Zamora-Martinez, and Rémi Martin-Fardon Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract A major challenge for the successful treatment of […]
Read More… from The paraventricular nucleus of the thalamus is recruited by both natural rewards and drugs of abuse: recent evidence of a pivotal role for orexin/hypocretin signaling in this thalamic nucleus in drug-seeking behavior (2014)
Pharmacol Rev. 2006 Mar;58(1):46-57. Spinazzi R1, Andreis PG, Rossi GP, Nussdorfer GG. Abstract Orexin-A and orexin-B are hypothalamic peptides that act via two G protein-coupled receptors, named orexin type 1 and type 2 receptors (OX1-Rs and OX2-Rs). The most studied biological functions of orexins are the central control of feeding and sleep, but in the […]
Read More… from Orexins in the regulation of the hypothalamic-pituitary-adrenal axis (2006)
Mol Biosyst. Author manuscript; available in PMC 2012 Jun 20. Published in final edited form as: Mol Biosyst. 2010 Aug; 6(8): 1366–1375. Published online 2010 Jun 7. doi: 10.1039/c003468a PMCID: PMC3379554 NIHMSID: NIHMS280225 Thomas Kodadek* and Di Cai Author information ► Copyright and License information ► The publisher’s final edited version of this article is […]
Read More… from Chemistry and Biology of Orexin Signaling (2010)
Annu Rev Pharmacol Toxicol. Author manuscript; available in PMC 2012 Feb 10. Published in final edited form as: Annu Rev Pharmacol Toxicol. 2011 Feb 10; 51: 243–266. doi: 10.1146/annurev-pharmtox-010510-100528 PMCID: PMC3058259 NIHMSID: NIHMS277744 Thomas E. Scammell1 and Christopher J. Winrow2 Author information ► Copyright and License information ► The publisher’s final edited version of this […]
Read More… from Orexin Receptors: Pharmacology and Therapeutic Opportunities (2012)
Front Behav Neurosci. 2013 May 20;7:43. doi: 10.3389/fnbeh.2013.00043. eCollection 2013. Carter ME1, de Lecea L, Adamantidis A. Abstract To survive in a rapidly changing environment, animals must sense their external world and internal physiological state and properly regulate levels of arousal. Levels of arousal that are abnormally high may result in inefficient use of internal […]
Read More… from Functional wiring of hypocretin and LC-NE neurons: implications for arousal (2013)
Neuropsychopharmacology. 2012 Aug; 37(9): 1999–2011. Published online 2012 May 9. doi: 10.1038/npp.2012.48 PMCID: PMC3398727 Laura Piccoli,1,4,5,6 Maria Vittoria Micioni Di Bonaventura,2,4,* Carlo Cifani,2,4 Vivian J A Costantini,1,5,6 Mario Massagrande,1,5,6 Dino Montanari,1,5,6 Prisca Martinelli,1,5,6 Marinella Antolini,1,5,6 Roberto Ciccocioppo,2 Maurizio Massi,2 Emilio Merlo-Pich,3 Romano Di Fabio,1,5,6 and Mauro Corsi1,5,6 Author information ► Article notes ► Copyright and […]
Read More… from Role of Orexin-1 Receptor Mechanisms on Compulsive Food Consumption in a Model of Binge Eating in Female Rats (2012)
Front Neurosci. 2014; 8: 26. Published online 2014 Feb 13. doi: 10.3389/fnins.2014.00026 PMCID: PMC3923148 Emilio Merlo Pich1,* and Sergio Melotto2 Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Fifteen years after the discovery of hypocretin/orexin a large body of […]
Read More… from Orexin1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use (2014)
Front Syst Neurosci. 2014 Nov 13;8:216. doi: 10.3389/fnsys.2014.00216. eCollection 2014. Hurley SW1, Johnson AK2. Abstract The hypothalamus has been recognized for its involvement in both maintaining homeostasis and mediating motivated behaviors. The present article discusses a region of the hypothalamus known as the lateral hypothalamic area (LHA). It is proposed that brain nuclei within the […]
Read More… from The role of the lateral hypothalamus and orexin in ingestive behavior: a model for the translation of past experience and sensed deficits into motivated behaviors (2014)
I have had the urge over the past few days to share my story, in the hope that it may help someone who needs tips or just some encouragement from someone in the same struggle. This is an account of my journey so far. So I started watching porn and masturbating when I was 12 […]
Read More… from Age 23 – ED cured. Feel like a new person, More confident, Urge to watch porn is gone
Front Psychol. 2015; 6: 396. Published online 2015 Apr 9. doi: 10.3389/fpsyg.2015.00396 PMCID: PMC4391226 Roberto Cattivelli,1,* Giada Pietrabissa,1,2 Martina Ceccarini,1,3 Chiara A. M. Spatola,1,2 Valentina Villa,1 Annalisa Caretti,1 Arianna Gatti,4 Gian Mauro Manzoni,1 and Gianluca Castelnuovo1,2 Author information ► Article notes ► Copyright and License information ► Being overweight is a growing problem worldwide, and […]
Read More… from ACTonFOOD opportunities of ACT to address food addiction (2015)