Cortisol Secretion Patterns In Addiction And Addiction Risk (2006)

Cortisol Secretion Patterns In Addiction And Addiction Risk

William R. Lovallo*
Int J Psychophysiol. 2006 March; 59(3): 195–202.

William R. Lovallo, Behavioral Sciences Laboratories (151A), Veterans Affairs Medical Center, 921 NE 13th Street, Oklahoma City, Oklahoma, 73104, United States;
* Tel.: +1 405 270 0501×3124; fax: +1 405 290 1839. E-mail address: [email protected]

Abstract
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The Influence of ΔFosB in the Nucleus Accumbens on Natural Reward Related Behavior (2008)

COMMENTS: Delta FosB is one the primary molecules of addiction. It rises, or accumulates, during an addiction process, reinforcing addictive behavior and rewiring of the brain. It rises whether the addiction is chemical or behavioral. This study shows that it accumulates during sexual activity and consumption of sugar. Researchers also found that sexual activity increased the consumption of sugar. Delta FosB may be involved in one addiction reinforcing another addiction. The question is – how does “over consumption” of porn affect Delta FosB?

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Read More… from The Influence of ΔFosB in the Nucleus Accumbens on Natural Reward Related Behavior (2008)

The Influence of ΔFosB in the Nucleus Accumbens on Natural Reward Related Behavior (2008)

COMMENTS: Delta FosB is one the primary molecules of addiction. It rises, or accumulates, during an addiction process, reinforcing addictive behavior and rewiring of the brain. It rises whether the addiction is chemical or behavioral. This study shows that it accumulates during sexual activity and consumption of sugar. Researchers also found that sexual activity increased the consumption of sugar. Delta FosB may be involved in one addiction reinforcing another addiction. The question is – how does “over consumption” of porn affect Delta FosB?

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Read More… from The Influence of ΔFosB in the Nucleus Accumbens on Natural Reward Related Behavior (2008)

DeltaFosB in The Nucleus Accumbens is Critical For Reinforcing Effects of Sexual Reward. (2010)

COMMENTS: Delta FosB is a marker for all addictions, both behavioral and chemical. As this molecule increases in the reward circuit so do addictive behaviors. It’s one of the molecules involved in neuroplastic changes. This experiment shows that it increases with sexual experience, similarly to how it does with drug addictions. In the experiment they employed genetic engineering to increase its levels beyond “normal”. This resulted in enhanced facilitation of sexual activity. We think this happens with porn addiction.

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Neuroplasticity in the Mesolimbic System Induced by Natural Reward and Subsequent Reward Abstinence. (2010)

COMMENTS: Study shows neuroplastic and behavioral changes in reward circuit can arise from sexual activity. These include the growth of neurons branches and stronger reaction to drugs. As usual, natural reinforcers and drugs have similar effects on the brain. I don’t know what to make of the key observation that these changes only occurred after a period of abstinence.

Pitchers KK, Balfour ME, Lehman MN, Richtand NM, Yu L, Coolen LM.
Biol Psychiatry. 2010 May 1;67(9):872-9. Epub 2009 Dec 16.
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Educating Your Therapist

Getting help for issues related to excessive porn use is a fine idea. However, many therapists have no conception of how addictive today’s hyperstimulating Internet porn is. Many were trained when static, softcore Playboy was porn, and before the recent brain science that is helping to explain the close parallels between extremely stimulating substances and […]

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(L) Binge Eaters Dopamine Levels Spike at Sight Smell of Food (2011)

COMMENTS: It’s food, but it’s a natural reinforcer, like sexual stimuli. This research demonstrates once again that binge patterns with natural reinforcers alter the reward/motivation pathways. Binge patterns in food and gambling have been shown to lower dopamine (D2) receptors. The numbed pleasure response. This leads to a craving for more dopamine stimulating stuff – […]

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