(L) Differences in dopamine may determine how hard people work Human study suggests biological basis for individual differences in behavior (2012)

COMMENTS: Higher dopamine in the reward circuitry (striatum, pre-frontal cortex) was reflected in more effort and motivation. Addictions lower reward circuitry dopamine and dopamine (D2) receptors. Differences in dopamine may determine how hard people work Human study suggests biological basis for individual differences in behavior Washington, DC — Whether someone is a “go-getter” or a “slacker” may […]

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Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB.(2010)

COMMENTS: Although both stress, drugs of abuse and certain natural rewards trigger an accumulation of DeltaFosB, stress activates different downstream cells and later different receptors and genes. In other words, addictions and resistance to stress rely on fundamentally different mechanisms FULL STUDY J Neurosci. 2010 Oct 27;30(43):14585-92. Vialou V, Maze I, Renthal W, LaPlant QC, […]

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DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses. (2010)

FULL STUDY scicurious explanation – For Stress Resiliance, thank DeltaFosB Nat Neurosci. 2010 June; 13(6): 745–752. Published online 2010 May 16. doi:  10.1038/nn.2551 Vincent Vialou,1 Alfred J. Robison,1,* Quincey C. LaPlant,1,* Herb E. Covington, III,1 David M. Dietz,1 Yoshinori N. Ohnishi,1 Ezekiell Mouzon,1 Augustus J. Rush, III,2 Emily L. Watts,1 Deanna L. Wallace,2,§ Sergio D. Iniguez,3 […]

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DeltaFosB-mediated alterations in dopamine signaling are normalized by a palatable high fat diet (2008)

FULL STUDY Biol Psychiatry. 2008 Dec 1;64(11):941-50. Epub 2008 Jul 26. Teegarden SL, Nestler EJ, Bale TL. Source Department of Animal Biology, University of Pennsylvania, Philadelphia, PA 19104-6046, USA. Abstract BACKGROUND: Sensitivity to reward has been implicated as a predisposing factor for behaviors related to drug abuse as well as overeating. However, the underlying mechanisms […]

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(CAUSE) Precursor or Sequela: Pathological Disorders in People with Internet Addiction Disorder (2011)

COMMENTS: A unique study. It follows first year university students to ascertain what percentage develop Internet addiction, and what risk factors may be in play. The unique aspect is that the research subjects had not used the Internet prior to enrolling in college. Hard to believe. After only one year of school, a small percentage were classified […]

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N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action (2011)

 FULL STUDY HERE J Psychiatry Neurosci. 2011 March; 36(2): 78–86.  doi: 10.1503/jpn.100057 PMCID: PMC3044191  Copyright © 2011 Canadian Medical Association Olivia Dean, BSc, PhD, Frank Giorlando, MBBS, BMedSc, and Michael Berk, MBBCh, MMed(Psych), PhD  Dean, Berk — Mental Health Research Institute, Parkville; Dean, Giorlando, Berk — Department of Clinical and Biomedical Sciences, Barwon Health, University […]

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The Great Porn Experiment – Given at TEDx (March, 2012)

Have our brains evolved to handle the hyperstimulation of today’s Internet enticements? Gary Wilson discusses the disturbing symptoms showing up in some heavy Internet users, the surprising reversal of those symptoms, and the science behind these phenomena. Empirical support for “The Great Porn Experiment” (2012) For comprehensive support for the claims presented in each slide […]

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Problematic Internet Use in High School Students in Guangdong Province China (2010)

COMMENTS: 12.5 % of high scholl students were found to were identified as problematic Internet users (PIUs). FULL STUDY with tables. PLoS One. 2011; 6(5): e19660. Published online 2011 May 6. doi: 10.1371/journal.pone.0019660 Copyright Wang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, […]

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Impact of addiction to internet on a number of psychiatric symptoms in students of Isfahan universities, Iran, 2010. (2012)

From the study: “problems due to Internet addiction, such as anxiety, depression, aggression, and job and educational dissatisfaction.” Correlation does not equal causation but we see symptoms  such as depression and anxiety remit through recovery from porn addiction. Int J Prev Med. 2012 Feb;3(2):122-7. Alavi SS, Alaghemandan H, Maracy MR, Jannatifard F, Eslami M, Ferdosi M. […]

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