TL;DR Nofap helped me dig my way out of depression, get an awesome job, get an awesome gf, and forgive and forget those who fucked me over in the past. Much thanks to all you beautiful bastards. 90 days ago I had no idea this day would come or any idea how my life would […]
Read More… from 90 days – Depression & social anxiety beat, got an awesome job & girlfriend
Proc Natl Acad Sci U S A. 2005 February 1; 102(5): 1737–1742. Published online 2005 January 21. doi: 10.1073/pnas.0409456102 PMCID: PMC547862 Neuroscience Satoru Takahashi,* Toshio Ohshima,† Andrew Cho,‡ Taduru Sreenath,*‡ Michael J. Iadarola,§ Harish C. Pant,¶ Yong Kim,∥ Angus C. Nairn,∥** Roscoe O. Brady,†† Paul Greengard,∥ and Ashok B. Kulkarni*‡‡‡ Author information ► Copyright and […]
Comments: Appears to show that Cdk5 causes down regulation of dopamine D2 receptors. Amazingly, translation factor deltafosb induces the production of Cdk5. Jeong J, Park Y-U, Kim D-K, Lee S, Kwak Y, et al. (2013) PLoS ONE 8(12): e84482. doi:10.1371/journal.pone.0084482 Abstract The dopamine D2 receptor (DRD2) is a key receptor that mediates dopamine-associated brain functions […]
Read More… from Cdk5 Phosphorylates Dopamine D2 Receptor and Attenuates Downstream Signaling (2013)
Post from Nofap Firstly, I want to thank and congradulate each and every one of you guys and gals for having the courage to take up this challenge, and special thanks to Gary Wilson, the moderator of “yourbrainonporn” for his hard work and reasearch on the subject. Note that English is not my first language […]
FULL STUDY – PDF College students’ heavy Internet use shares symptoms of addiction December 18, 2013 by Linda Fulps Young adults who are heavy users of the Internet may also exhibit signs of addiction, say researchers at Missouri University of Science and Technology, Duke University Medical Center and the Duke Institute of Brain Sciences in […]
Read More… from An Empirical Study on Symptoms of Heavier Internet Usage among Young Adults (2013)
Front Psychiatry. 2011; 2: 64. PMCID: PMC3225760 Marco Diana1,* Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Dopamine (DA) transmission is deeply affected by drugs of abuse, and alterations in DA function are involved in the various phases of […]
Read More… from The Dopamine Hypothesis of Drug Addiction and Its Potential Therapeutic Value (2011)
Front Psychiatry. 2013; 4: 72. Published online 2013 August 1. doi: 10.3389/fpsyt.2013.00072 George F. Koob1,* Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Drug addiction can be defined by a three-stage cycle – binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation […]
Read More… from Addiction is a Reward Deficit and Stress Surfeit Disorder (2013)
Urol Int. 2013 Nov 21. Ludwig W, Phillips M. Source Department of Urology, Center for Sexual Health, George Washington University, Washington, D.C., USA. Abstract There are a significant number of men under 40 who experience erectile dysfunction (ED). In the past, the vast majority of cases were thought to be psychogenic in nature. Studies have […]
Read More… from Organic Causes of Erectile Dysfunction in Men Under 40 (2013)
PLoS One. 2011; 6(9): e24992. Published online 2011 September 27. doi: 10.1371/journal.pone.0024992 PMCID: PMC3181252 Albino J. Oliveira-Maia,1,*¤a¤b Craig D. Roberts,1 Q. David Walker,2 Brooke Luo,1 Cynthia Kuhn,2 Sidney A. Simon,1,3,5 and Miguel A. L. Nicolelis1,3,4,5,6 Xiaoxi Zhuang, Editor Author information ► Article notes ► Copyright and License information ► This article has been cited by […]
2010 January 1. Published in final edited form as: Neuropharmacology. 2009; 56(Suppl 1): 139–148. SHELLY B. FLAGEL,* HUDA AKIL,* and TERRY E. ROBINSON† Author information ► Copyright and License information ► The publisher’s final edited version of this article is available at Neuropharmacology See other articles in PMC that cite the published article. Go […]