Oktoobar 19th, 2014 ee Cilmi-nafsiga & Maskaxda /
Dhammaan bini'aadamka waxay leeyihiin maskaxda dabiiciga ah ee dabiiciga ah. Hadda cilmi baaris cusub, oo lagu soo bandhigay Congresska ECNP ee Berlin, ayaa ogaatay in nidaamka opioid ee khamaarka nafsadda ee ka jawaab celiya si ka duwan kuwa mutadawiciinta ah ee caafimaadka qabta. Shaqada waxaa qabtay koox cilmi baarayaal ah oo ka socda London iyo Cambridge, waxaana maalgeliyey Golaha Cilmi-baarista Caafimaadka. Shaqadan waxaa lagu soo bandhigay Kuliyada Yurub ee Neuropsychopharmacology ee Berlin.
Khamaaristu waa dhaqdhaqaaq baahsan oo ku saabsan 70% marka la eego khamaarka dadka Britishka marmar. Si kastaba ha ahaatee Shakhsiyaadka qaarkood, qamaaraadka qamaarka ayaa xakameynaya oo ka qaata sifooyinka mukhaadaraadka - khamaarka noolaha, oo loo yaqaano khamaar dhibaato. 2007 Survey Reporting Prevention Index 1 ayaa ku qiyaastay in 0.6% dadka qaangaarka ah ee UK ay dhibaato ka qabaan khamaarka, taas oo u dhiganta qiyaastii 300,000, oo ku saabsan guud ahaan dadweynaha magaalada sida Swansea. Xaaladdan waxaa lagu qiyaasay inuu yahay 0.5-3% Yurub.
Cilmi-baadhayaashu waxay qaadeen khamaarayaasha pathologist 14 iyo kuwa 15 oo caafimaad qaba, waxayna isticmaaleen baaritaanka PET (Positron Emission Tomography) si loo cabbiro heerarka daaweynta opioid ee maskaxda labada kooxood. Receptors Kuwani waxay u oggolaanayaan unugyada isgaadhsiinta unugyada - waxay u eg yihiin qufulka neurotransmitter ama kiimikada, sida opioid endogen opioids oo loo yaqaan 'endorphins,' sida fure u ah. Cilmi baadhayaashu waxay ogaadeen inaysan jirin farqi u dhexeeya heerarka aqbalaadda ee khamaarayaasha hawada iyo kuwa aan qamaarka. Tani way ka duwantahay cabitaanka khamriga, heroinka ama kookearka ee kororka lagu arko heerarka daaweynta opioid.
Dhammaan maadooyinka ayaa la siiyey kiniin amphetamine kaas oo sii deynaya endorfin, kuwaas oo ah dabiiciga dabiiciga ah maskaxda oo lagu celiyo baaritaanka PET. Siidaynta noocan oo kale ah - oo loo yaqaan 'rush endorphin' - ayaa sidoo kale loo maleynayaa inay ku dhacdo aalkolo ama jimicsi. Baadhitaanka 'PET scan' wuxuu muujiyey in khamaarayaasha cudurada wadnaha ay sii daayeen wax ka yar endorphins marka loo eego tabaruceyaasha aan khamaarka ciyaarin iyo sidoo kale in tani ay la xiriirto amfetamine oo keenaya farxad yar sida ay tabaruceyaashu u soo sheegeen (iyadoo la adeegsanayo su'aalo is-qiimayn ah oo loo yaqaan 'Fududeynta qaabka qiimeynta wareysiga amphetamine miisaan ', ama SAIRS).
Cilmi-baariste Dr Inge Mick ayaa yiri:
Shaqadeena, waxaan dhihi karnaa labo shay. Marka hore, maskaxda khamaarayaasha cudurada wadnaha waxay uga jawaabaan si ka duwan kicintan marka loo eego maskaxda tabaruceyaasha caafimaadka qaba. Marka labaadna, waxay umuuqataa in khamaarayaasha cudurada wadata kaliya aysan helin dareen la mid ah xamaasadda sida tabaruceyaasha caafimaadka qaba. Tani waxay u mari kartaa si uun sharaxaad ku saabsan sababta khamaarku u noqday balwad ”.
“Tani waa daraasaddii ugu horreysay ee sawir qaadista PET si loo eego ku lug lahaanshaha nidaamka opioid ee khamaarka noolaha, taas oo ah balwad dhaqan. Markii aan eegnay shaqadii hore ee ku saabsan balwadaha kale, sida aalkolada, waxaan filaynay in khamaarayaasha cudurada wadata ay kordhin lahaayeen soo dhoweeyeyaasha opiate ee aynaan helin, laakiin waxaan ka helnay isbadal ba'an oo lafilayo in opioids-ka halista ah ee amphetamine. Natiijooyinkaani waxay soo jeedinayaan ku lug lahaanshaha nidaamka opioid ee khamaarka noolaha iyo inay ka duwanaan karto qabatinka walxaha sida aalkolada. Waxaan rajeyneynaa in mustaqbalka fog ay tani naga caawin karto inaan horumarinno habab cusub oo lagu daaweeyo khamaarka noolaha.
Isagoo ka hadlaya magaca ECNP, Professor Wim van den Brink (Amsterdam), Guddoomiyaha Guddiga Cilmi-baarista ee Berlin, ayaa yiri:
“Waqtigaan la joogo, waxaan ogaanay in daaweynta ka hortagga opioid-ka sida naltrexone iyo nalmefene ay u muuqato inay saameyn togan ku leedahay daaweynta cudurada qamaarka, iyo in natiijooyinka ugu wanaagsan ee daawooyinkan laga helo dhibaatooyinkaas khamaarayaasha leh taariikhda qoyska ee ku tiirsanaanta khamriga. Laakiin warbixintan ka soo baxday Dr Mick iyo asxaabtiisuba waa shaqo xiiso leh, haddii la xaqiijiyana waxay albaabada u furi kartaa habab cusub oo lagu daweeyo khamaarayaasha cudurada keena.
Waxaa bixiya Kulliyadda Yurub ee Neuropsychopharmacology
Khamaarka noolaha wuxuu xiriir la leeyahay nidaamka opioid ee maskaxda wax laga badalay. Oktoobar 19, 2014. http://medicalxpress.com/news/2014-10-pathological-gambling-opioid-brain.html
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