Neuropharmacology. 2016 Dec;111:223-230. doi: 10.1016/j.neuropharm.2016.09.006. Cameron CM1, Wightman RM2, Carelli RM3. Abstract Cocaine addiction is a chronic relapsing disorder that is difficult to treat in part because addicts relapse even after extended periods of abstinence. Given the importance of the mesolimbic dopamine (DA) system in drug addiction, we sought to characterize cocaine abstinence induced changes […]
Read More… from One month of cocaine abstinence potentiates rapid dopamine signaling in the nucleus accumbens core (2016)
Neuropsychopharmacology. 2015 Feb; 40(3): 728–735. Published online 2014 Oct 8. Prepublished online 2014 Sep 12. doi: 10.1038/npp.2014.238 PMCID: PMC4289961 Erin S Calipari,1,2 Cody A Siciliano,2 Benjamin A Zimmer,2,3 and Sara R Jones2,* Abstract Although traditional sensitization paradigms, which result in an augmentation of cocaine-induced locomotor behavior and dopamine (DA) overflow following repeated experimenter-delivered cocaine injections, […]
Read More… from Brief Intermittent Cocaine Self-Administration and Abstinence Sensitizes Cocaine Effects on the Dopamine Transporter and Increases Drug Seeking (2014)
Neuropsychopharmacology. 2013 Nov; 38(12): 2456–2466. Published online 2013 Jul 10. Prepublished online 2013 Jun 10. doi: 10.1038/npp.2013.147 PMCID: PMC3799065 Attilio Iemolo,1 Angelo Blasio,1 Stephen A St Cyr,1 Fanny Jiang,1 Kenner C Rice,2 Valentina Sabino,1 and Pietro Cottone1,* Abstract Highly palatable foods and dieting are major contributing factors for the development of compulsive eating in obesity […]
Read More… from CRF–CRF1 Receptor System in the Central and Basolateral Nuclei of the Amygdala Differentially Mediates Excessive Eating of Palatable Food (2013)
Behav Pharmacol. Author manuscript; available in PMC 2014 Feb 25. Behav Pharmacol. 2012 Sep; 23(0): 593–602. doi: 10.1097/FBP.0b013e328357697f PMCID: PMC3934429 NIHMSID: NIHMS554308 Attilio Iemolo,a,b,* Marta Valenza,a,b,c,* Lisa Tozier,b Clifford M. Knapp,b Conan Kornetsky,b Luca Steardo,dValentina Sabino,a,b and Pietro Cottonea,b Abstract The increased availability of highly palatable foods is a major contributing factor toward the development of compulsive eating in obesity and eating disorders. It has […]
Read More… from Withdrawal from chronic, intermittent access to a highly palatable food induces depressive-like behavior in compulsive eating rats (2012)
Physiol Behav. Author manuscript; available in PMC 2014 Apr 10. Physiol Behav. 2013 Apr 10; 0: 21–31. Published online 2013 Mar 13. doi: 10.1016/j.physbeh.2013.03.005 PMCID: PMC3648600 NIHMSID: NIHMS455916 Sylvie Lardeux, James J. Kim, and Saleem M. Nicola* Abstract Binge eating disorders are characterized by discrete episodes of rapid and excessive food consumption. In rats, giving […]
Read More… from Intermittent access to sweet high-fat liquid induces increased palatability and motivation to consume in a rat model of binge consumption (2013)
On October 1st I told myself that I would quit and I found the perseverance to stay strong to this very day. In the last 5 months the following things have happened. I lost over 22 pounds, and dropped 6% Bodyfat. Girls definitely notice this and I habitually diet now, workout regularly and eat clean. […]
Read More… from Picked up two jobs, Expanded my hobbies, Connect with people on a deeper level, Make others laugh pretty easily, Bonding with my family a lot more.
Front Psychol. 2017 Apr 10;8:526. doi: 10.3389/fpsyg.2017.00526. Deng LY1, Liu L2, Xia CC2,3, Lan J2, Zhang JT4,5, Fang XY2. Abstract Craving, as a central feature of addiction and a precursor of relapse, is targeted recently in addiction intervention. While Internet gaming disorder (IGD), conceptualized as a behavioral addiction, is lack of effective treatment practice and […]
Read More… from (REMISSION) Craving Behavior Intervention in Ameliorating College Students’ Internet Game Disorder: A Longitudinal Study (2017)
I´m male 28. Had a severe case of delayed ejaculation and had low sensitivity. When I first joined this site, I was reading the success stories here and damn how I wished I could some day write my own one. And here it is! MY STORY: My problem was that I had troubles reaching orgasm… […]
Read More… from Age 28 – Had a severe case of delayed ejaculation and had low sensitivity
Frutos, A.M. & Merrill, R.M. Sexuality & Culture (2017). doi:10.1007/s12119-017-9438-6 Abstract The purpose of the current study was to evaluate explicit sexual movie use among men and women in the United States according to relationship, lifestyle, work, financial, religious, and political factors. Analyses involved 11,372 adults who responded to questions about demographics and explicitly sexual […]
Read More… from Explicit Sexual Movie Viewing in the United States According to Selected Marriage and Lifestyle, Work and Financial, Religion and Political Factors (2017)
I made it, so can you! Here’s my story. I had been hooked to P for more than 20 years, and my sexual life was a complete mess. I had PIED and suffered gay HOCD, I even acted out, and I was so confused. I didn’t dare date a girl for many years. I felt […]
Read More… from Age 37 – HOCD & PIED: Right now, I can assure you those issues are over