Separate neural circuits control cravings vs. healthy eating, researchers find (2015)

COMMENTS: Two landmark studies demonstrating that separate circuits exist for compulsive sugar consumption – or as YBOP calls it, ‘a binge mechanism‘. It has always been thought that behavioral addictions arise from only alterations of “normal circuits”.  While this does occur, it is now evident that separate ‘bingeing circuits’ also exist. This makes evolutionary sense. […]

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Extinction circuits for fear and addiction overlap in prefrontal cortex (2009)

Learn Mem. 2009 Apr 20;16(5):279-88. doi: 10.1101/lm.1041309. Peters J1, Kalivas PW, Quirk GJ. Abstract Extinction is a form of inhibitory learning that suppresses a previously conditioned response. Both fear and drug seeking are conditioned responses that can lead to maladaptive behavior when expressed inappropriately, manifesting as anxiety disorders and addiction, respectively. Recent evidence indicates that […]

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Decoding Neural Circuits that Control Compulsive Sucrose Seeking (2015) (BINGE MECHANISM)

COMMENTS: A study that isolates the circuit responsible for compulsive sugar consumption. This circuit is separate from the normal food consumption circuit, and seems to be the “binge mechanism”. Does compulsive sexual behavior has its own circuit? Edward H. Nieh2 Gillian A. Matthews2 Stephen A. Allsop2 Kara N. Presbrey Christopher A. Leppla Romy Wichmann Rachael Neve Craig P. Wildes Kay M. Tye […]

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