J Clin Invest. Feb 1, 2008; 118(2): 454–461. doi: 10.1172/JCI33946 PMCID: PMC2214707 Jessica N. Cleck and Julie A. Blendy Author information ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Sustained exposure to various psychological stressors can exacerbate neuropsychiatric disorders, including drug addiction. Addiction is […]
Read More… from Making a bad thing worse: adverse effects of stress on drug addiction (2008)
Philos Trans R Soc Lond B Biol Sci. Oct 12, 2008; 363(1507): 3113–3123. Published online Jul 24, 2008. doi: 10.1098/rstb.2008.0094 PMCID: PMC2607326 George F Koob1,* and Michel Le Moal2 Author information ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract The conceptualization of drug addiction […]
Read More… from Neurobiological mechanisms for opponent motivational processes in addiction (2008)
Neuropharmacology. Author manuscript; available in PMC Jan 1, 2010. Neuropharmacology. 2009; 56(Suppl 1): 18–31. Published online Aug 7, 2008. doi: 10.1016/j.neuropharm.2008.07.043 PMCID: PMC2637927 NIHMSID: NIHMS86836 George F. Koob, Ph.D. Author information ► Copyright and License information ► The publisher’s final edited version of this article is available at Neuropharmacology See other articles in PMC that […]
Read More… from Neurobiological Substrates for the Dark Side of Compulsivity in Addiction (2009)
Brain Res. Author manuscript; available in PMC Feb 16, 2011. Brain Res. Feb 16, 2010; 1314C: 3. Published online Nov 11, 2009. doi: 10.1016/j.brainres.2009.11.008 PMCID: PMC2819562 NIHMSID: NIHMS164224 George F. Koob, Ph.D. Abstract Drug addiction is a chronically relapsing disorder characterized by a compulsion to seek and take drugs, the development of dependence, and the […]
Read More… from The Role of CRF and CRF-related Peptides in the Dark Side of Addiction (2014)
tl;dr: nofap works, I am staying on it, AMA. Make yourself a warm cup of something nice, position yourself into your favourite reading position and go with me though this 300 days NoFap journey summary. Why NoFap? I wanted to do NoFap even before I found this sub. The reason for that is that I […]
Read More… from Age 32 – 300 days, skin condition healed, calm, empathic, approaching strangers
I just wanted to say thanks basically for the guys running YBOP – you’ve been a life-saving form of support. Just reading what others have been through and achieved is a massive help. I’ve just completed 90 days without looking at porn. I had a calendar up on my wall and ticked every day off […]
Read More… from Age 30s – ED: when you quit you get back a sense of masculinity and assuredness
LINK TO POST November 19, 2014 by Andrew Smiler Andrew Smiler discusses a straightforward and often effective solution to adult video-induced erectile difficulties. NSFW: This article contains adult themes and frank discussion of human sexuality and health.* Jim came to me for therapy because he was having a hard time getting it up during sex. I […]
Read More… from Online Videos Causing IRL Erectile Problems? by Andrew Smiler PhD
Results after achieving 300 days of NoFap What I have found out is that the best way to deal with it is cram your life into deliberate awkward public situations so you cannot sneak peek at porn when the urge arrives. Work on tasks that really challenge you both mentally and physically. Take time out […]
Read More… from Age 33 – Married: 301 days of not doing something can help you achieve so much other somethings
J Neurosci. Author manuscript; available in PMC Oct 18, 2012. Published in final edited form as: J Neurosci. Apr 18, 2012; 32(16): 5549–5552. doi: 10.1523/JNEUROSCI.5958-11.2012 PMCID: PMC3377379 NIHMSID: NIHMS370916 K. E. Demos, T. F. Heatherton, and W. M. Kelley Author information ► Copyright and License information ► The publisher’s final edited version of this article […]
Read More… from Individual Differences in Nucleus Accumbens Activity to Food and Sexual Images Predict Weight Gain and Sexual Behavior (2012)
Specific brain neurons responsible for nicotine addiction Until now, it has been thought that drug addiction results from two separate systems in the brain: the reward system, activated when a person uses a drug, and the stress system, activated during withdrawal. But a new study suggests there are specific neurons in the brain’s reward system […]
Read More… from VTA active during use and withdrawal: CRF neurons found within VTA (2014)