Optogenetic and chemogenetic insights into the food addiction hypothesis (2014)

Front Behav Neurosci. 2014 Feb 28;8:57. doi: 10.3389/fnbeh.2014.00057. eCollection 2014. Krashes MJ, Kravitz AV. Author information Abstract Obesity is clinically diagnosed by a simple formula based on the weight and height of a person (body mass index), but is associated with a host of other behavioral symptoms that are likely neurological in origin. In recent […]

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Dopamine, time, and impulsivity in humans (2010)

J Neurosci. 2010 Jun 30;30(26):8888-96. doi: 10.1523/JNEUROSCI.6028-09.2010. Pine A1, Shiner T, Seymour B, Dolan RJ. Author information Abstract Disordered dopamine neurotransmission is implicated in mediating impulsiveness across a range of behaviors and disorders including addiction, compulsive gambling, attention-deficit/hyperactivity disorder, and dopamine dysregulation syndrome. Whereas existing theories of dopamine function highlight mechanisms based on aberrant reward […]

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Endogenous cortisol levels are associated with an imbalanced striatal sensitivity to monetary versus non-monetary cues in pathological gamblers (2014)

Front Behav Neurosci. 2014 Mar 25;8:83. doi: 10.3389/fnbeh.2014.00083. eCollection 2014. Li Y1, Sescousse G2, Dreher JC1. Author information Abstract Pathological gambling is a behavioral addiction characterized by a chronic failure to resist the urge to gamble. It shares many similarities with drug addiction. Glucocorticoid hormones including cortisol are thought to play a key role in […]

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Age 19 – 1 year ago I was a borderline-depressed socially anxious shy guy with no dating prospects

1 Year Ago… I was nearing the end of my first year in college. I PMO’d close to every day. I seriously wondered what could possibly be so wrong in my life that made me so unhappy. By random dumb luck, I heard about reddit and randomly found /r/nofap on April 24th. I looked over […]

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After 30 years of PMO – I kept an an erection during intercourse for the first time ever in my life

82 days is a weird number to post about, but I hit a big milestone today. Quick background. I’m divorced and had married my first girlfriend (and first sexual partner). That lasted over a decade and I am ashamed to admit that PMO caused me to have almost no sex life. The divorce wasn’t solely […]

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