Image: Cocaine users show low activity in the medial orbitofrontal cortex Regular cocaine users have difficulties in feeling empathy for others and they exhibit less prosocial behavior. A study at the Psychiatric Hospital of the University of Zurich now suggests that cocaine users have social deficits because social contacts are less rewarding for them. Social […]
Read More… from Cocaine users enjoy social interactions less
Comments: Appears to show that Cdk5 causes down regulation of dopamine D2 receptors. Amazingly, translation factor deltafosb induces the production of Cdk5. Bottom line Deltafosb plays a major role in both sensitization & desensitization Jeong J, Park Y-U, Kim D-K, Lee S, Kwak Y, et al. (2013) PLoS ONE 8(12): e84482. doi:10.1371/journal.pone.0084482 Abstract The dopamine […]
Read More… from Cdk5 Phosphorylates Dopamine D2 Receptor and Attenuates Downstream Signaling (2013)
A growing ‘NoFap’ movement of young men are saying no to porn, and the masturbation that goes with it Earlier this year, Armando, a 23-year-old technician from Oklahoma (who didn’t want to give his last name), was browsing the online news and discussion board Reddit when he clicked a button called “random.” It took him […]
Read More… from Will quitting porn improve your life? (Maclean’s – Canada)
I haven’t really been active on this forum, always just brushing through peoples posts to find something inspirational or something i could connect with in my situation. So i decided not to be so selfish and give back a little, because you never know how your story, no matter how inconsequential it may seem to […]
Read More… from Age 22 – (ED) A different perspective (Why your pillow might just be the cure)
COMMENTS: Authors suggest that lack of sexual activity leads to lower testosterone. In another study they hypothesize that this may be related to the stress of ED, or may be due to the resumption of sexual activity itself. Hard to sort out as all the subjects suffered from ED, and had lower testosterone. Int J […]
The reasons to start NoFap in the first place to be honest was getting a gf (never had one) and getting laid. Not because I wanted to change my whole life or anything. It started out with lots of edging and some pics. But of course I failed with this because and it didn’t really […]
I’m 29 and from November I suffered of ED, now I stop watching porn and masturbation for only 9 days and I can see some good news, I have erection only with the touch and my dick stay up also when I’m on my feet, in fact in those 6 months i can’t see it […]
Cereb Cortex. 2010 Jul;20(7):1613-29. doi: 10.1093/cercor/bhp225. Epub 2009 Oct 29. Geier CF, Terwilliger R, Teslovich T, Velanova K, Luna B. Author information Laboratory of Neurocognitive Development, Department of Psychiatry and Psychology, Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA 15213, USA. [email protected] Abstract The nature of immature reward processing and the […]
The British Journal of Psychiatry (2011) 199: 87-89 doi: 10.1192/bjp.bp.110.088146 Henrietta Bowden-Jones, MRCPsych, DOccMed, MD Luke Clark, DPhil + Author Affiliations Imperial College London, and the National Problem Gambling Clinic, Central North West London NHS Foundation Trust Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, UK + Author Notes Henrietta Bowden-Jones […]
Read More… from Pathological gambling: a neurobiological and clinical update (2011)
I am 28 and come from Europe. This is my first post ever and I want to share my experience with you. My post will be long since I want to share every bit of detail with you. This journey has made me consider life in so many new ways and it has, indeed, made […]
Read More… from Age 28 – 9 months: From aggressive hatred to spiritual calmness