I love the 90 day challenge. Certainly that seems contradictory to that title above. However, it’s true. I love it. But there is a problem, and I’m sure I’m not the only one to notice it. What I’m speaking of is the conundrum of what happens after 90 days. Are we cured? Let me give […]
Read More… from Why the 90 day challenge sucks!
Autoradiograms showing dopamine D2 receptor levels in the brains of obese and lean rats at four months of age. Half of the rats, top row of images, had been given unrestricted access to food during the previous three months while the other half, bottom row of images, were kept on a restricted diet. Compared […]
Read More… from Food Restriction Increases Dopamine D2 Receptors In Rats (2007)
Trends Cogn Sci. 2011 Jan;15(1):37-46. doi: 10.1016/j.tics.2010.11.001. Epub 2010 Nov 24. Volkow ND, Wang GJ, Baler RD. Source National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA. [email protected] Abstract The ability to resist the urge to eat requires the proper functioning of neuronal circuits involved in top-down control to oppose the […]
Read More… from Reward, dopamine and the control of food intake: implications for obesity (2011)
J Nutr. 2009 March; 139(3): 623–628. doi: 10.3945/jn.108.097584 PMCID: PMC2714381 Nicole M. Avena 1 , 2 , Pedro Rada 1 , and Bartley G. Hoebel 1 , * + Author Affiliations 1Department of Psychology, Princeton University, Princeton, NJ 08540 and 2The Rockefeller University, New York, NY 10021 *To whom correspondence should be addressed. E-mail: [email protected]. […]
Read More… from Sugar and Fat Bingeing Have Notable Differences in Addictive-like Behavior (2009)
History – Richard Nixon had been president for roughly 6 months, mankind had taken it’s first steps on the moon and a neighbor showed me some hard-core porn. I was at the very first days of puberty and the intense stimulation from the sight of these photos left an incredibly deep impression upon me at […]
Read More… from Age 58 – Metamorphosis, shame gone
Neuropharmacology. 2011 Dec;61(8):1470-6. doi: 10.1016/j.neuropharm.2011.08.046. Sim-Selley LJ, Cassidy MP, Sparta A, Zachariou V, Nestler EJ, Selley DE. Source Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA. Abstract The stable transcription factor ΔFosB is induced in the nucleus accumbens (NAc) by chronic […]
Read More… from Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens (2011)
COMMENTS: Evidence that deltafosb leaves behind traces long after recovery from addiction. Specifically addiction causes epigenetic changes, that result in much faster induction of deltafosb when relapse occurs. This explains how relapsing, even after years can rapidly escalate to a full blown addicted state. J Neurosci. Author manuscript; available in PMC 2013 January 25. J […]
Read More… from Drug experience epigenetically primes Fosb gene inducibility in rat nucleus accumbens (2012)
Hello all! We’ve all read the benefits on nofap and let me tell you they are all real. I am a 27 year old (today!) recovering porn and lust addict, also recovering from a long bout with PIED. I know this is a really rough thing to deal with, especially since we tend to get […]
Read More… from Age 27 – ED. 120+ days of no P/M
The Art of Tricking the Brain Currently, we’re winning. There are about seven billion of us who roam this lonely rock. We’ve inhabited every continent, crossed every ocean, and developed the most intricate methods to extract natural resources from what we call home. None of this would have been possible without two of our most […]
Read More… from Essay about porn written for college English class
Addict Biol. 2013 Jan 24. doi: 10.1111/adb.12033. Blasio A, Steardo L, Sabino V, Cottone P. Source Laboratory of Addictive Disorders, Departments of Pharmacology and Psychiatry, Boston University School of Medicine, Boston, MA, USA. Abstract Binge eating disorder is an addiction-like disorder characterized by excessive food consumption within discrete periods of time. This study was aimed […]
Read More… from Opioid system in the medial prefrontal cortex mediates binge-like eating (2013)