Reward, dopamine and the control of food intake: implications for obesity (2011)

Trends Cogn Sci. 2011 Jan;15(1):37-46. doi: 10.1016/j.tics.2010.11.001. Epub 2010 Nov 24. Volkow ND, Wang GJ, Baler RD. Source National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA. [email protected] Abstract The ability to resist the urge to eat requires the proper functioning of neuronal circuits involved in top-down control to oppose the […]

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Sugar and Fat Bingeing Have Notable Differences in Addictive-like Behavior (2009)

J Nutr. 2009 March; 139(3): 623–628. doi:  10.3945/jn.108.097584 PMCID: PMC2714381 Nicole M. Avena 1 , 2 , Pedro Rada 1 , and Bartley G. Hoebel 1 , * + Author Affiliations 1Department of Psychology, Princeton University, Princeton, NJ 08540 and 2The Rockefeller University, New York, NY 10021 *To whom correspondence should be addressed. E-mail: [email protected]. […]

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Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens (2011)

Neuropharmacology. 2011 Dec;61(8):1470-6. doi: 10.1016/j.neuropharm.2011.08.046. Sim-Selley LJ, Cassidy MP, Sparta A, Zachariou V, Nestler EJ, Selley DE. Source Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA. Abstract The stable transcription factor ΔFosB is induced in the nucleus accumbens (NAc) by chronic […]

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Drug experience epigenetically primes Fosb gene inducibility in rat nucleus accumbens (2012)

COMMENTS: Evidence that deltafosb leaves behind traces long after recovery from addiction. Specifically addiction causes epigenetic changes, that result in much faster induction of deltafosb when relapse occurs. This explains how relapsing, even after years can rapidly escalate to a full blown addicted state. J Neurosci. Author manuscript; available in PMC 2013 January 25. J […]

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Opioid system in the medial prefrontal cortex mediates binge-like eating (2013)

Addict Biol. 2013 Jan 24. doi: 10.1111/adb.12033. Blasio A, Steardo L, Sabino V, Cottone P. Source Laboratory of Addictive Disorders, Departments of Pharmacology and Psychiatry, Boston University School of Medicine, Boston, MA, USA. Abstract Binge eating disorder is an addiction-like disorder characterized by excessive food consumption within discrete periods of time. This study was aimed […]

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