(CAUSE) Precursor or Sequela: Pathological Disorders in People with Internet Addiction Disorder (2011)

COMMENTS: A unique study. It follows first year university students to ascertain what percentage develop Internet addiction, and what risk factors may be in play. The unique aspect is that the research subjects had not used the Internet prior to enrolling in college. Hard to believe. After only one year of school, a small percentage were classified […]

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DeltaFosB in the Nucleus Accumbens Regulates Food Reinforced Instrumental Behavior and Motivation (2006)

FULL STUDY The Journal of Neuroscience, 6 September 2006, 26(36): 9196-9204; doi: 10.1523/JNEUROSCI.1124-06.2006 Peter Olausson1, J. David Jentsch2, Natalie Tronson1, Rachel L. Neve3, Eric J. Nestler4, and Jane R. Taylor1 1.Correspondence should be addressed to Jane R. Taylor, Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, Ribicoff Research Facilities, Connecticut Mental […]

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N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action (2011)

 FULL STUDY HERE J Psychiatry Neurosci. 2011 March; 36(2): 78–86.  doi: 10.1503/jpn.100057 PMCID: PMC3044191  Copyright © 2011 Canadian Medical Association Olivia Dean, BSc, PhD, Frank Giorlando, MBBS, BMedSc, and Michael Berk, MBBCh, MMed(Psych), PhD  Dean, Berk — Mental Health Research Institute, Parkville; Dean, Giorlando, Berk — Department of Clinical and Biomedical Sciences, Barwon Health, University […]

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DeltaFosB: A sustained molecular switch for addiction (2001)

COMMENTS: As later studies will reveal DeltaFosB is the common molecular switch for both drug and behavioral addictions. It’s a transcription factor which means it affects what genes are turned on or off. As stated elsewhere, addictive drugs only hijack normal mechanisms. That’s why it’s silly to suggest that behavioral addictions cannot exist.  FULL STUDY […]

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Transcriptional mechanisms underlying addiction-related structural plasticity (2010)

Mol Interv. 2010 Aug;10(4):219-30. Maze I, Russo SJ. Source Fishberg Department of Neuroscience and Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY, USA. Abstract Drug addiction is marked by long-lasting changes in behavior that result, in part, from altered patterns of gene expression within limbic forebrain regions, such as the nucleus accumbens […]

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Another angle on the science behind the flatline

This scientist doesn’t speak in terms of addiction-related changes, but he describes how learning changes the brain. Addiction is pathological learning. This exchange appeared on Reddit.com under “AskScience.” Why does abstaining from porn/masturbation/orgasm temporarily decrease as opposed to increase libido? In /r/nofap there’s a move to ‘reboot’ one’s overstimulated brain to restore the sensitivity to […]

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Age 32 – Married, German

Day 33 I’m from Germany. I am 32 and what you would probably call a very good looking guy. I’m married to a beautiful woman and I work in the central department of a world famous company. Before that I had finished high school with a A+ degree (called 1,0 Abitur in Germany) and then […]

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