Search Results for: brain change

 FULL STUDY HERE J Psychiatry Neurosci. 2011 March; 36(2): 78–86.  doi: 10.1503/jpn.100057 PMCID: PMC3044191  Copyright © 2011 Canadian Medical Association Olivia Dean, BSc, PhD, Frank Giorlando, MBBS, BMedSc, and Michael Berk, MBBCh, MMed(Psych), PhD  Dean, Berk — Mental Health Research Institute, Parkville; Dean, Giorlando, Berk — Department of Clinical and Biomedical Sciences, Barwon Health, University […]

Read More… from N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action (2011)

COMMENTS: Eric Nestler lays out much of the detail about DeltaFosB and addiction. (More has since been discovered.) Simply put, DeltaFosB rises in the reward circuit in response to chronic consumption of drugs of abuse and certain natural rewards. Its evolutionary purpose is to have you get it while the getting is good (food and sex) […]

Read More… from Transcriptional mechanisms of addiction: role of ΔFosB (2008)

COMMENTS: As later studies will reveal DeltaFosB is the common molecular switch for both drug and behavioral addictions. It’s a transcription factor which means it affects what genes are turned on or off. As stated elsewhere, addictive drugs only hijack normal mechanisms. That’s why it’s silly to suggest that behavioral addictions cannot exist.  FULL STUDY […]

Read More… from DeltaFosB: A sustained molecular switch for addiction (2001)

Mol Interv. 2010 Aug;10(4):219-30. Maze I, Russo SJ. Source Fishberg Department of Neuroscience and Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY, USA. Abstract Drug addiction is marked by long-lasting changes in behavior that result, in part, from altered patterns of gene expression within limbic forebrain regions, such as the nucleus accumbens […]

Read More… from Transcriptional mechanisms underlying addiction-related structural plasticity (2010)

This scientist doesn’t speak in terms of addiction-related changes, but he describes how learning changes the brain. Addiction is pathological learning. This exchange appeared on Reddit.com under “AskScience.” Why does abstaining from porn/masturbation/orgasm temporarily decrease as opposed to increase libido? In /r/nofap there’s a move to ‘reboot’ one’s overstimulated brain to restore the sensitivity to […]

Read More… from Another angle on the science behind the flatline

From this Reddit NoFap post I’ve been reading a bunch of peoples posts and commenting some on this r/nofap for 3 weeks now. Lately, I feel, posts come from a more negative perspective which really bugs me. I would like to change that in the form of this post. Also, I would like to give […]

Read More… from Guide to staying (porn) fap-free

COMMENTS:  Dr. Nora Volkow, director of the National Institute on Drug Abuse states that food addiction is every bit as real as drug addiction. She makes the point, like we have several times- that enticing junk food can hook a far greater percentage than do addictive drugs. several TIME Magazine: Can Food Really Be Addictive? Yes, […]

Read More… from (L) Can Food Really Be Addictive? Yes, Says Dr. Nora Volkow, director of the National Institute on Drug Abuse (2012)