Exercise elevates dopamine D2 receptor in a mouse model of Parkinsons disease In vivo imaging with (18F) fallypride (2010)

Comments: In a mouse model of Parkinson’s, treadmill exercise increased dopamine D2 receptors . Addictions cause a decline in D2 receptors which is partly the cause of desensitization. Another reason to exercise.

Movement Disorders
Volume 25, Issue 16, pages 2777-2784, 15 December 2010

Marta G. Vučcković MSc1,2, Quanzheng Li PhD3, Beth Fisher PT, PhD4, Angelo Nacca PhD5, Richard M. Leahy PhD3, John P. Walsh PhD6, Jogesh Mukherjee PhD7, Celia Williams BSc2, Michael W. Jakowec PhD2,4, Giselle M. Petzinger MD2,4*

Abstract

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Aerobic Exercise Reduces Cannabis Craving (2011)

Thursday, July 21, 2011

Regular readers will recall my recent posts on the notion that the benefits of regular exercise on body weight are largely mediated by the positive impact on caloric intake rather than by the number of calories burnt.

This notion is based on the idea that exercise modulates eating behaviour by reducing stress, improving mood, and perhaps, even by reducing the ‘reward’ response of palatable foods.

The latter assumption, is supported by a recent stud by Maciej Buchowski and colleagues from Vanderbilt University, Nashville, Tennessee, published in PLoS.

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(L) Is the Pleasure Molecule Dopamine? (2008)

COMMENTS: One controversy surrounding dopamine is whether it is behind feelings of pleasure. It’s well established that dopamine produces desire and cravings or “wanting”, but is it involved in “liking”. Researchers have separated the liking from wanting in food experiments, and determined dopamine is not involved in the hedonic aspects of food. But does this also apply to sex, friendly interactions and love? Studies clearly shoe that self reports of pleasure parallel dopamine levels.

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(L) A classic instinct – salt appetite – is linked to drug addiction (2011)

Comments: It’s common knowledge among addiction researchers that behavioral addictions and substance addictions involve the same pathways and similar or overlapping mechanisms. This is another study corroborating this paradigm. Addictions hijack our normal pathways in the hub of the reward circuit, which is why they affect us in so many ways.
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ARTICLE

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Tales of Porn-Related ED 2

A small sampling from MedHelp (roughly 2000 posts on different threads) of various men who have experienced porn-related ED.

  • I’m 27 years old and have been dealing with this problem since the age of 24. It’s funny how this condition can gradually set in. I challenge each of you to attempt to discover when the condition first showed its colors. Many of you will be tempted to say “well when I was with this person I was unable to perform”. but if you look a deeper you may notice that the condition began to set in way earlier than that.

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(L) When Fatty Feasts Are Driven by Automatic Pilot (2011)

Comments: Another study validating the concept of a binge trigger, as described in our videos and articles.

By TARA PARKER-POPE
New York Times
July 11, 2011

“Bet you can’t eat just one” (as the old potato-chip commercials had it) is, of course, a bet most of us end up losing. But why? Is it simple lack of willpower that makes fatty snacks irresistible, or are deeper biological forces at work?

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