Last June I stopped fapping, for the purpose of restoring the peen to its long-lost glory, and to stop feeling like a total degenerate. This is for all y’all still dealing with the struggle, to learn about the long road to recovery. The central theme in my story is my relationship with a girl who […]
Read More… from Age 25 – ED & delayed ejaculation cured. Porn related fetishes almost gone
J Neurosci. 2007 Mar 14;27(11):2837-45. Muschamp JW1, Dominguez JM, Sato SM, Shen RY, Hull EM. Abstract The role of hypocretin (orexin; hcrt/orx) neurons in regulation of arousal is well established. Recently, hcrt/orx has been implicated in food reward and drug-seeking behavior. We report here that in male rats, Fos immunoreactivity (ir) in hcrt/orx neurons increases […]
Read More… from A role for hypocretin (orexin) in male sexual behavior (2007)
Front Psychiatry. 2013; 4: 68. Published online 2013 Aug 1. doi: 10.3389/fpsyt.2013.00068 PMCID: PMC3730062 Subhashini Srinivasan,1 Masroor Shariff,2 and Selena E. Bartlett2,* Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract There is emerging evidence that individuals have the capacity […]
Horm Behav. Author manuscript; available in PMC 2011 Aug 1. Published in final edited form as: Horm Behav. 2010 Aug; 58(3): 397–404. Published online 2010 Jun 10. doi: 10.1016/j.yhbeh.2010.06.004 PMCID: PMC2917508 Andrea R. Di Sebastiano,1 Sabrina Yong-Yow,2 Lauren Wagner,3 Michael N. Lehman,1 and Lique M. Coolen1,2 Author information ► Copyright and License information ► The […]
Pharmacol Rev. 2006 Mar;58(1):46-57. Spinazzi R1, Andreis PG, Rossi GP, Nussdorfer GG. Abstract Orexin-A and orexin-B are hypothalamic peptides that act via two G protein-coupled receptors, named orexin type 1 and type 2 receptors (OX1-Rs and OX2-Rs). The most studied biological functions of orexins are the central control of feeding and sleep, but in the […]
Read More… from Orexins in the regulation of the hypothalamic-pituitary-adrenal axis (2006)
Curr Opin Pharmacol. Author manuscript; available in PMC 2013 Oct 7. Published in final edited form as: Curr Opin Pharmacol. 2009 Feb; 9(1): 39–45. doi: 10.1016/j.coph.2008.12.018 PMCID: PMC3791851 NIHMSID: NIHMS468294 Matthew E. Carter, Jana Schaich Borg, and Luis de Lecea Author information ► Copyright and License information ► The publisher’s final edited version of this […]
Read More… from The brain hypocretins and their receptors: mediators of allostatic arousal (2009)
Annu Rev Pharmacol Toxicol. Author manuscript; available in PMC 2012 Feb 10. Published in final edited form as: Annu Rev Pharmacol Toxicol. 2011 Feb 10; 51: 243–266. doi: 10.1146/annurev-pharmtox-010510-100528 PMCID: PMC3058259 NIHMSID: NIHMS277744 Thomas E. Scammell1 and Christopher J. Winrow2 Author information ► Copyright and License information ► The publisher’s final edited version of this […]
Read More… from Orexin Receptors: Pharmacology and Therapeutic Opportunities (2012)
Front Behav Neurosci. 2013 May 20;7:43. doi: 10.3389/fnbeh.2013.00043. eCollection 2013. Carter ME1, de Lecea L, Adamantidis A. Abstract To survive in a rapidly changing environment, animals must sense their external world and internal physiological state and properly regulate levels of arousal. Levels of arousal that are abnormally high may result in inefficient use of internal […]
Read More… from Functional wiring of hypocretin and LC-NE neurons: implications for arousal (2013)
Front Syst Neurosci. 2014 Nov 13;8:216. doi: 10.3389/fnsys.2014.00216. eCollection 2014. Hurley SW1, Johnson AK2. Abstract The hypothalamus has been recognized for its involvement in both maintaining homeostasis and mediating motivated behaviors. The present article discusses a region of the hypothalamus known as the lateral hypothalamic area (LHA). It is proposed that brain nuclei within the […]
**everything I’m going to say, is probably not my original idea. In fact, it very well might have been drawn from you reading this who knows. I’ve read countless peoples journals, articles, watched videos, read books, and my thoughts are largely a reiteration of what others have said before me. So again, I take no […]
Read More… from Age 19 – I always hoped I die at like 30 so I could escape my “miserable life”