Front. Integr. Neurosci., 20 July 2012 | doi: 10.3389/fnint.2012.00049 Jeff A. Beeler1*, Cristianne R. M. Frazier2 and Xiaoxi Zhuang1,2 1Department of Neurobiology, The University of Chicago, Chicago, IL, USA 2Committee on Neurobiology, The University of Chicago, Chicago, IL, USA Accumulating evidence indicates integration of dopamine function with metabolic signals, highlighting a potential role for dopamine […]
Read More… from Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources (2012)
Know what? I feel like a snake after it sheds its skin. Though it is far from over…the urges for porn are on a very low controllable level, but rewiring to the real thing just started. Right now, I just sense the seeds growing that I planted last year in july when I read an […]
Read More… from Age 24 – (ED) 90 days: Escape From the “Comfort-Zone Prison”
Image: Cocaine users show low activity in the medial orbitofrontal cortex Regular cocaine users have difficulties in feeling empathy for others and they exhibit less prosocial behavior. A study at the Psychiatric Hospital of the University of Zurich now suggests that cocaine users have social deficits because social contacts are less rewarding for them. Social […]
Read More… from Cocaine users enjoy social interactions less
Image: Cocaine users show low activity in the medial orbitofrontal cortex Regular cocaine users have difficulties in feeling empathy for others and they exhibit less prosocial behavior. A study at the Psychiatric Hospital of the University of Zurich now suggests that cocaine users have social deficits because social contacts are less rewarding for them. Social […]
Read More… from Cocaine users enjoy social interactions less
Neurosci Biobehav Rev. 2011 Aug;35(8):1704-12. doi: 10.1016/j.neubiorev.2011.04.003. Epub 2011 Apr 15. Sturman DA, Moghaddam B. Author information Abstract Adolescence is a period of increased behavioral and psychiatric vulnerabilities. It is also a time of dramatic structural and functional neurodevelopment. In recent years studies have examined the precise nature of these brain and behavioral changes, and […]
Read More… from The neurobiology of adolescence: changes in brain architecture, functional dynamics, and behavioral tendencies (2011)
Comments: Appears to show that Cdk5 causes down regulation of dopamine D2 receptors. Amazingly, translation factor deltafosb induces the production of Cdk5. Bottom line Deltafosb plays a major role in both sensitization & desensitization Jeong J, Park Y-U, Kim D-K, Lee S, Kwak Y, et al. (2013) PLoS ONE 8(12): e84482. doi:10.1371/journal.pone.0084482 Abstract The dopamine […]
Read More… from Cdk5 Phosphorylates Dopamine D2 Receptor and Attenuates Downstream Signaling (2013)
A growing ‘NoFap’ movement of young men are saying no to porn, and the masturbation that goes with it Earlier this year, Armando, a 23-year-old technician from Oklahoma (who didn’t want to give his last name), was browsing the online news and discussion board Reddit when he clicked a button called “random.” It took him […]
Read More… from Will quitting porn improve your life? (Maclean’s – Canada)
Cereb Cortex. 2010 Jul;20(7):1613-29. doi: 10.1093/cercor/bhp225. Epub 2009 Oct 29. Geier CF, Terwilliger R, Teslovich T, Velanova K, Luna B. Author information Laboratory of Neurocognitive Development, Department of Psychiatry and Psychology, Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA 15213, USA. [email protected] Abstract The nature of immature reward processing and the […]
Read More… from Immaturities in reward processing and its influence on inhibitory control in adolescence (2010)
The British Journal of Psychiatry (2011) 199: 87-89 doi: 10.1192/bjp.bp.110.088146 Henrietta Bowden-Jones, MRCPsych, DOccMed, MD Luke Clark, DPhil + Author Affiliations Imperial College London, and the National Problem Gambling Clinic, Central North West London NHS Foundation Trust Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, UK + Author Notes Henrietta Bowden-Jones […]
Read More… from Pathological gambling: a neurobiological and clinical update (2011)
EMBO Rep. 2014 Jan 1;15(1):12-6. doi: 10.1002/embr.201338222. Wallace P. Author information Johns Hopkins University’s Center for Talented Youth (CTY) online programs and IT. http://embor.embopress.org/content/15/1/12 Although ‘Internet addiction disorder’ is not officially recognized as a disorder by the psychiatric community—it was not included in the recently released Diagnostic and Statistical Manual of Mental Disorder V (DSM‐V), […]
Read More… from Internet addiction disorder and youth: There are growing concerns about compulsive online activity and that this could impede students’ performance and social lives (2014)