Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive (2012)

FULL STUDY – PDF ABSTRACT Nature (2012) doi:10.1038/nature11436 Received 13 May 2011Published online 19 September 2012 Julia C. Lemos, Matthew J. Wanat, Jeffery S. Smith, Beverly A. S. Reyes, Nick G. Hollon, Elisabeth J. Van Bockstaele, Charles Chavkin  & Paul E. M. Phillips Stressors motivate an array of adaptive responses ranging from ‘fight or flight’ […]

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Membrane androgen receptors may mediate androgen reinforcement. (2010)

Psychoneuroendocrinology. 2010 Aug;35(7):1063-73. Epub 2010 Feb 6.   Sato SM, Johansen JA, Jordan CL, Wood RI. Source Department of Cell & Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Abstract Anabolic-androgenic steroid (AAS) abuse is widespread. Moreover, AAS are reinforcing, as shown by self-administration in rodents. However, the receptors […]

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Adolescents and Androgens, Receptors and Rewards (2008)

COMMENTS: Excellent review of almost all the relevant research on androgen receptors, dopamine and sexual function. Fantastic drawing the the hypothalamus-reward circuit interrelationships.   Horm Behav. 2008 May; 53(5): 647–658. Published online 2008 February 13. doi:  10.1016/j.yhbeh.2008.01.010 Satoru M. Sato,1 Kalynn M. Schulz,2 Cheryl L. Sisk,2 and Ruth I. Wood1 Author information ► Copyright and […]

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Changes in dopamine D2-receptor binding are associated to symptom reduction after psychotherapy in social anxiety disorder (2012)

Citation: Translational Psychiatry (2012) 2, e120; doi:10.1038/tp.2012.40 S Cervenka1, E Hedman1,2, Y Ikoma1,3, D Radu Djurfeldt1, C Rück1, C Halldin1 and N Lindefors1 1Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden 2Department of Clinical Neuroscience, Osher Center for Integrative Medicine and Division of Psychology, Karolinska Institutet, Stockholm, Sweden 3Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan Correspondence: […]

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90 days – I feel rewired. Female friends I’ve known for many years look at me differently

Greetings all. Here are my impressions after 90 days of nofap. –I wouldn’t have done it without the nofap community. The counter helped a lot, especially at the start. The anonymity also helps a lot, I have not revealed to anyone in person that I am on nofap, though I will when the time is […]

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Electroacupuncture Decreases Excessive Alcohol Consumption Involving Reduction of FosB/ΔFosB Levels in Reward-Related Brain Regions (2012)

COMMENTS: Study found that alcohol self-administration induced a pronounced accumulation of deltafosb, Specifically applied electroacupuncture greatly inhibited alcohol consumption, which was paralleled by a decline in deltafosb. In addiction blocking DeltaFosB, blocks the key effects of drug exposure. The mechanism of action suggests that electroacupuncture suppress dopamine, thus inhibit accumulation of deltfosb.   PLoS One. […]

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