Opposing role of dopamine D1 and D2 receptors in modulation of rat nucleus accumbens noradrenaline release (1999)

J Neurosci. 1999 May 15;19(10):4123-31. Vanderschuren LJ1, Wardeh G, De Vries TJ, Mulder AH, Schoffelmeer AN. Abstract The role of dopamine receptors in the modulation of nucleus accumbens noradrenaline release was investigated in superfused rat brain slices. At concentrations of </=1 microM, dopamine enhanced, whereas at higher concentrations dopamine inhibited electrically evoked [3H]noradrenaline release. The […]

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Internet addictive individuals share impulsivity and executive dysfunction with alcohol-dependent patients (2014)

Front. Behav. Neurosci., 25 August 2014 | doi: 10.3389/fnbeh.2014.00288 Zhenhe Zhou*, Hongmei Zhu, Cui Li and Jun Wang Department of Psychiatry, Wuxi Mental Health Center, Wuxi, China ABSTRACT Internet addiction disorder (IAD) should belong to a kind of behavioral addiction. Previous studies indicated that there are many similarities in the neurobiology of behavior and substance […]

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Age 23 – From a socially-inept porn addict living with his mum, to in my own house, preparing to launch my own company

Over a year or two ago now, I sat down in front of my computer after work, fired up facebook and resumed the all-familiar position that I had become all too accustomed to for the evening. Relentless scrolling, browsing, masturbating, everything I could do to distract myself from the monotony of what my life had […]

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Gambling Rats and Gambling Addiction: Reconciling the Role of Dopamine in Irrationality (2013)

Guillaume Sescousse1,* and  Hanneke E.M. den Ouden1,2,* +Show Affiliations ↵*G.S. and H.E.M.d.O. equally contributed to this work. The Journal of Neuroscience, 20 February 2013, 33(8): 3256-3258; doi: 10.1523/JNEUROSCI.5828-12.2013 Full Text Full Text (PDF) Next Section Introduction Pathological gambling is a behavioral addiction that is characterized by excessive (monetary) risk-taking in the face of negative consequences, […]

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1 year – ED, laziness, back pain gone. Much more productive, emotional, focused, motivated, talkative, and engaging.

Before I stumbled upon NoFap one year ago, I was fapping 1-3 times a day, yes, that was 365 – 1095 times a year for around 20 years. After reading posts, and exploring more, and putting in hard work, I’ve lowered that frequency. Here are my one year stats since I started this journey- please […]

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