What is “the chaser?”

“Chaser” is the term often used to describe intense cravings that follow orgasm, perhaps immediately or perhaps the following day. They likely arise from neurochemical changes naturally triggered by climax. Men often report that the chaser eases over time as the brain finds a new balance during rebooting. For more, read Do You Need a […]

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Dual roles of dopamine in food and drug seeking: the drive-reward paradox (2013)

Biol Psychiatry. Author manuscript; available in PMC 2014 May 1. Published in final edited form as: Biol Psychiatry. 2013 May 1; 73(9): 819–826. Published online 2012 Oct 5. doi:  10.1016/j.biopsych.2012.09.001 PMCID: PMC3548035 NIHMSID: NIHMS407698 Roy A. Wise Abstract The question of whether (or to what degree) obesity reflects addiction to high energy foods often narrows […]

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A role for synaptic plasticity in the adolescent development of executive function (2013)

Transl Psychiatry. 2013 March; 3(3): e238. Published online 2013 March 5. doi:  10.1038/tp.2013.7 PMCID: PMC3625918 L D Selemon1,* Author information ► Article notes ► Copyright and License information ► Go to: Abstract Adolescent brain maturation is characterized by the emergence of executive function mediated by the prefrontal cortex, e.g., goal planning, inhibition of impulsive behavior […]

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Dopamine Genetics and Function in Food and Substance Abuse (2013)

J Genet Syndr Gene Ther. 2013 February 10; 4(121): 1000121. doi:  10.4172/2157-7412.1000121 K Blum,1,3,9,* M Oscar-Berman,2 D Barh,3 J Giordano,5 and MS Gold1 Author information ► Copyright and License information ► Go to: Abstract Having entered the genomics era with confidence in the future of medicine, including psychiatry, identifying the role of DNA and polymorphic […]

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Dopamine Genetics and Function in Food and Substance Abuse (2013)

J Genet Syndr Gene Ther. 2013 February 10; 4(121): 1000121. doi:  10.4172/2157-7412.1000121 K Blum,1,3,9,* M Oscar-Berman,2 D Barh,3 J Giordano,5 and MS Gold1 Author information ► Copyright and License information ► Go to: Abstract Having entered the genomics era with confidence in the future of medicine, including psychiatry, identifying the role of DNA and polymorphic […]

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The Neurobiology and Genetics of Impulse Control Disorders: Relationships to Drug Addictions (2008)

COMMENTS: Review clearly delineating OCD from behavioral addictions. Biochem Pharmacol. 2008 January 1; 75(1): 63–75. Published online 2007 July 3. doi:  10.1016/j.bcp.2007.06.043 PMCID: PMC2222549 NIHMSID: NIHMS37091 Judson A. Brewer, MD PhD and Marc N. Potenza, MD PhD Author information ► Copyright and License information ► The publisher’s final edited version of this article is available […]

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Probing Compulsive and Impulsive Behaviors, from Animal Models to Endophenotypes: A Narrative Review (2010)

COMMENTS: Makes a clear distinction between compulsive behaviors such as OCD, and impulsive behaviors such gambling addiction. Deniers of behavioral addictions often say that those with porn addiction simply have a compulsive behavior, rather than an addiction. This refutes this bogus claim. Neuropsychopharmacology. 2010 February; 35(3): 591–604. Published online 2009 November 25. doi:  10.1038/npp.2009.185 PMCID: […]

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