Behav Brain Res. 2011 Mar 1;217(2):354-62. Epub 2010 Nov 9. Greenwood BN, Foley TE, Le TV, Strong PV, Loughridge AB, Day HE, Fleshner M. Department of Integrative Physiology, Center for Neuroscience, University of Colorado, Boulder, CO, USA. [email protected] Abstract The mesolimbic reward pathway is implicated in stress-related psychiatric disorders and is a potential target of […]
COMMENTS: DeltaFosb is a molecular switch that accumulates in the brain with chronic administration of addictive drugs, high fat, high sugar and wheel running. It alters the brain to cause sensitization to whatever one is over-consuming. It is a transcription factor that turns on and off genes that alter structure and communication in the reward […]
FULL STUDY Biol Psychiatry. 2008 Dec 1;64(11):941-50. Epub 2008 Jul 26. Teegarden SL, Nestler EJ, Bale TL. Source Department of Animal Biology, University of Pennsylvania, Philadelphia, PA 19104-6046, USA. Abstract BACKGROUND: Sensitivity to reward has been implicated as a predisposing factor for behaviors related to drug abuse as well as overeating. However, the underlying mechanisms […]
Hey guys this is my first post on NoFap, I’m 22 and have been a lurker here for some time now discovered your brain on porn (YBOP) late December and from then on have been rebooting since the 1st of January. Had tried in the past to give up fapping and porn but failed. I […]
Read More… from Age 22 – ED, long flatline – masturbation helped
COMMENTS: This is different from the Kenny rat study (2010), in which unlimited access caused obesity and addictio-related brain chnages. However, the kenny rats had access to a variety of high fat high sugar goodies. Either way, it is the binging beyond normal satity that appears to activate deltafosb, which inititaes sensitization. Binge eating may lead to addiction like behaviors […]
Read More… from (L) Binge eating may lead to addiction like behaviors (2012)
COMMENTS: Detailed review of dopamine and the nucleus accumbens in reward and aversion. FULL STUDY William A. Carlezon, Jr.1 and Mark J. Thomas2 Author information ► Copyright and License information ► The publisher’s final edited version of this article is available at Neuropharmacology See other articles in PMC that cite the published article. Go to: Abstract The […]
Day 22 Why did it take me so long to find this place?! So here’s my story, 31 years old, moderately successful in my career, fairly attractive, healthy, do endurance stuff, cycling, running, triathlons all the time but I’ve had a piece missing for quite a while and I couldn’t figure out what it was. […]
Read More… from Age 31 – ED, disgusting monkey hidden in a dark room
8-25 I am 18 years old, I discovered pornography quite early on in life around 10 or eleven years old, I remember from the earliest moment I always was turned on by pornography. I would look at pictures of naked girls, and stuff, it then elevated to heterosexual video porn, then like most, I discover […]
FULL STUDY Behav Neurosci. 2009 Apr;123(2):397-407. Freet CS, Steffen C, Nestler EJ, Grigson PS. Source Department of Neural and Behavioral Sciences, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. [email protected] Abstract Rodents suppress intake of saccharin when it is paired with a drug of abuse (Goudie, Dickins, & Thornton, 1978; Risinger & Boyce, […]
COMMENTS: a review by the top researcher on obesity and food addiction. FULL STUDY Volume 69, Issue 4, 24 February 2011, Pages 664–679 http://dx.doi.org/10.1016/j.neuron.2011.02.016, Review Paul J. Kenny1, , 1 Laboratory of Behavioral and Molecular Neuroscience, Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA ________________________________________ Food is consumed in order to maintain […]
Read More… from Reward Mechanisms in Obesity: New Insights and Future Directions (2011)