J Urol. 1997 Nov;158(5):1764-7.
mohloli o moholo
Mokhatlo oa mokhatlo oa d'Etude de la Pathologie de l'Appareil Reproducteur et de la Psychosomatique, Lille, France.
inahaneloang
MORERO:
Re shebile sephetho sa serum testosterone le boikemisetso ba prolactin ho bakuli ba 1,022 ba boletsoeng ka lebaka la ho se sebetse hantle ha erectile mme re bapisa data le nalane, liphetho tsa tlhahlobo ea 'mele, lipatlisiso tse ling tsa etiological le litlamorao tsa kalafo ea endocrine ho hlakola melao ea tlhahlobo ea endocrine e theko e boima le tšoaea boikarabello ba 'nete ba tlhekefetso ea li-hormone.
LISEBELISOA LE MEKHOA:
Testosterone le prolactin li ne li khethiloe ke radioimmunoassay. Mokuli e mong le e mong o ile a hlahlojoa testosterone mme 451 e ile ea hlahlojoa bakeng sa prolactin motheong oa takatso e tlase ea thobalano, gynecomastia kapa testosterone e tlase ho 4 ng./ml. Boikemisetso bo ile ba phetoa hangata haeba ho ne ho ka hlaha litholoana tse sa tloaelehang. Liphetho tsa Prolactin li ne li bapisoa le tsa sehlopha sa pele sa bakuli ba 1,340 ba nang le bothata ba ho se sebetse hantle le ho ikemisetsa ha prolactin. Litekanyetso tsa mantlha tsa tliliniki e ileng ea lekoa mabapi le ho atleha boitekong ba li-hormone e ne e le takatso e tlase ea thobalano, liteko tse nyane le gynecomastia. Pheko ea Endocrine e ne e na le testosterone heptylate kapa gonadotropin ea chorionic ea motho ka hypogonadism le bromocriptine bakeng sa hyperprolactinemia.
LIKOTSO:
Testosterone e ne e le tlase ho 3 ng./ml. ho bakuli ba 107 empa e tloaelehileng ho 40% ka boikemisetso bo phetoa. Ho ata ha testosterone e tlase khafetsa ho eketsehile ka lilemo (4% pele ho lilemo tsa 50 le 9% 50 lilemo kapa ho feta). Lihlahala tse peli tsa pituitary li ile tsa fumanoa kamora qeto ea testosterone. Boholo ba maemo a mang a tlaase a testosterone bo ne bo bonahala bo bakoa ke ho se sebetse hantle ha hyporganalamic dysfunction ka lebaka la serum e tloaelehileng ea li-luteinizing le prolactin le ho ba le karolo e fokolang feela ho dysfunction ea erectile (ntlafatso e hlakileng ho 16 ea 44 [36%] feela ka mor'a kalafo ea androgen, hoseng ho tloaelehileng kapa li-erections tsa nocturnal ho 30% le litlatsetso tse hlakileng tsa vasculogenic ho 42%. Ho khetholla testosterone feela maemong a takatso e tlase ea thobalano kapa tlhahlobo e sa tloaelehang ea 'mele e ka be e fetisitse 40% ea linyeoe tse nang le testosterone e tlase, ho kenyelletsa 37% ea tseo hamorao li ntlafalitsoeng ke kalafo ea androgen. Prolactin e fetisitse 20 ng./ml. ho banna ba 5 mme e ne e le ntho e tloaelehileng ho 2 ha e pheta boikemisetso. Ke 1 prolactinoma feela e fumanoeng. Lintlha tsena li tlaase ho feta tseo re li fumaneng lilemong tsa ho qetela tsa 2 (prolactin e kholo ho feta 20 ng./ml. Ka 1.86% ea bakuli ba 1,821, prolactinomas ho 7, 0.38%). Bromocriptine ka sebele e ne e sebetsa maemong a nang le prolactin e kholo ho feta 35 ng./ml. (8 ea 12 ha e bapisoa le 9 feela ea linyeoe tsa 22 tse nang le prolactin pakeng tsa 20 le 35 ng./ml.). Testosterone e ne e le tlase ka tlase ho 50% ea linyeoe tse nang le prolactin e kholo ho feta 35 ng./ml.
CONCLUSIONS:
Litlamorao tse tlase le litlamorao tsa testosterone e tlase le prolactin e phahameng ho dysfunction ea erectile li ke ke tsa hlakisa boikemisetso ba bona ba kemiso. Leha ho le joalo, maano a tekanyetso a sa sebetseng a khothalelitsoeng ho fihlela joale a lahleheloa ke 40 ho 50% ea linyeoe tse ntlafalitsoeng ka endocrine therapy le tumello ea pituitary. Hona joale re buella hore pele lilemo tsa 50 lilemo tsa testosterone li ikemisetse feela maemong a takatso e tlase ea thobalano le tlhahlobo e sa tloaelehang ea mmele empa e le hore e lekantsoe ho banna bohle ba baholo ho feta lilemo tsa 50. Prolactin e lokela ho khethoa feela maemong a takatso e tlase ea thobalano, gynecomastia le / kapa testosterone e tlase ho 4 ng./ml.
;