Front Neuroendocrinol. 2008 Oct; 29 (4): 490-506. Doi: 10.1016 / j.yfrne.2007.12.002. Epub 2008 Jan 3.
Lefapha la Cell & Neurobiology, Keck Sekolo sa Bongaka sa Univesithi ea Southern California, 1333 San Pablo Street, BMT 401, Los Angeles, CA 90033, USA. [imeile e sirelelitsoe]
inahaneloang
Anabolic-androgenic steroids (AAS) ke lithethefatsi tsa tlhekefetso. Li nkuoa ka bongata ke baatlelete le ba bang ho eketsa ts'ebetso, ka litlamorao tse mpe tsa bophelo bo botle. Ka lebaka leo, ho 1991 testosterone le AAS e amanang le eona li ile tsa phatlalatsoa e le lintho tse laoloang. Leha ho le joalo, tlhekefetso e lekanang le boikarabello ba AAS ha bo hlahe ka botlalo. Ho batho, ho thata ho khetholla litlamorao tse tobileng tsa psychoactive tsa AAS ho matlafatso ka lebaka la litlamorao tsa tsamaiso ea tsona ea anabolic. Leha ho le joalo, ho sebelisa boikhethelo ba sebaka le ho itaola, liphuputso ho liphoofolo li bontšitse hore AAS e tiisa maemong ao ho bapala lipapali ha ho na thuso. Ntle le moo, AAS e arolelana libaka tsa ts'ebetso ea boko le lits'ebetso tsa neurotransmitter tse tšoanang le lithethefatsi tse ling tsa tlhekefetso. Ka ho khetheha, bopaki ba morao-rao bo hokahanya AAS le li-opioids. Ho batho, tlhekefetso ea AAS e amana le ts'ebeliso ea meriana ea opioid. Ho liphoofolo, overdose ea AAS e hlahisa matšoao a tšoanang le opioid overdose, mme AAS e fetola tšebetso ea sistimi ea opioid ea endo native.
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