LIQETO: Boithuto bo senola li-nucleus tse bokellaneng e le setsi sa bokahohle ba thobalano. Sebopeho sena se seholo empa se le matla se laola meputso eohle le phetoho ea ho ba naha e lemalloang.
J Neurosci. 2012 Feb 1; 32 (5): 1672-86.
Matsumoto J, Urakawa S, Hori E, de Araujo MF, Sakuma Y, Ono T, Nishijo H.
mohloli o moholo
Science Emotional Science, Univesithi ea Toyama, Toyama 930-0194, Japan.
inahaneloang
Boithuto ba nakong e fetileng bo bontšitse hore mokokotlo oa "nucleus accumbens" (NAc) oa rat ea monna o kenya letsoho liketsong tsa eona tsa thobalano; leha ho le joalo, ha ho na lithuto tse fetileng tse kileng tsa etsa lipatlisiso ka mesebetsi ea neuronal mokokotlong oa banna NA NAc nakong ea boitšoaro ba thobalano. Ho etsa lipatlisiso ka taba ena, re tlaleha liketso tsa unit e le 'ngoe khetla ea NAc ea likhoto tsa banna nakong ea boitšoaro ba thobalano. Ho li-neuron tsa 123 NAc tse ithutoang, li-neuron tsa 53, 47, le 40 li bontsitse haholo litekanyetso tsa ho thunya ka linako tse fapaneng nakong ea ho kenella, ho ikoetlisa ka botona le botšehali, le ho hlaseloa ha basali.
Mefuta e 'meli ea li-neurc tsa li-neurc [li-kufunga tsa spiking interneurons (pFSIs) le li-spiny neurons tse mahareng (pMSNs) li ile tsa arabela ka tsela e fapaneng nakong ea boitšoaro ba thobalano.
Taba ea mantlha, li-pFS tse ngata ho feta tsa li-PMSN li bonts'a likarabo tse thibelang takatso ka ho kenella le ho ikoetlisa ka botšehali, ha li-pFSIs le li-PMSN li ile tsa arabela ka mokhoa o ts'oanang le ho ts'oaroa ha basali.
Taba ea bobeli, li-pFSIs le li-PMSN li arabetse ka tsela e fapaneng ho khothaletsa ntle le ho kenella.
Ntle le moo, ts'ebetso ea neuron ea mokokotlo oa nec e ne e fapane haholo ka mekhahlelo e fapaneng ea boitšoaro ba thobalano, le palo ea li-neuron tsa NAc tse nang le "delta oscillation", e amanang le thibelo ea boitšoaro, le ts'ebetso e phahameng ea gamma, e amanang le pono ea moputso, e eketsehile kamora ho emisoa .
Ka kopanelo, sephetho sa rona se bonts'a hore khetla ea NAc e amehile ka botebo boits'oarong ba thobalano, 'me liphetoho mesebetsing ea lepolanka ea NAc li amana le ts'ebetso ea boitšoaro ba thobalano, likhakanyo kapa maemo a amanang le boitšoaro ba thobalano, ts'ebetso e amanang le moputso, le thibelo ea thobalano. boits'oaro kamora ho emisoa.
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