Andrologia. 2018 Oct 1: e13160. Doi: 10.1111 / and.13160.
Chen G1,2, Chen J2, Yang B2, Yu W2, Chen Y3, Dai Y2.
inahaneloang
Ho se sebetse hantle ka tsela e sa sebetseng ke bothata ka mekhoa e sa tsejoeng e bohareng. Liphetoho mosebetsing oa boko ho amygdala li hlokometsoe ho bakuli ba batho. Boithuto bona bo ne bo ikemiselitse ho fuputsa mokhoa oa dopamine ho amygdala ea basolateral ea likhoto tsa banna tse nang le dysfunction e sa sebetseng. Re sebelisitse khatello ea maikutlo e sa foleng ho qobella ho se sebetse hantle ka mokhoa oa ho se sebetse hantle. Kamora ho pepesetsoa khatello ea maikutlo e fokolang ea nako e telele, teko ea tšebeliso ea sucrose, liteko tsa boitšoaro ba thobalano le tlhahlobo ea apomorphine li ile tsa sebelisoa ho khetha likhoto tse tepelletsang joaloka khatello ea methapo e sa sebetseng joaloka likhoto tse sa sebetseng tsa erectile. Boitšoaro ba thobalano ba likhoto tsena kamora ho kenngoa bohareng ba dopamine D1 / D2 receptor agonist / antagonist bo ile ba bonoa. Maemo a polelo a dopamine D1 / D2 receptors le tyrosine hydroxylase ho amygdala ea basol le ona a ile a lekanngoa. Liphetho tsa tlhahlobo ea tšebeliso ea sucrose, tlhahlobo ea boitšoaro ba thobalano le tlhahlobo ea apomorphine li bonts'itse mokhoa o atlehileng oa ho se sebetse oa 'mele oa ho se sebetse. Ho kenella ha bohareng ba dopamine D2 receptor agonist ho eketse keketseho ea ho kenella lipapatsong tsa mohlala. Maemo a tlase a tyrosine hydroxylase le dopamine D2 receptor ho amygdala ea basolateral li ile tsa bonoa ka litoeba tse nang le bothata ba ho se sebetse ha erectile. Liphetho tsena li fana ka maikutlo a hore ho senyeha ha dopamine D2 receptor tsela tseleng ea basolateral amygdala ho ka kenya letsoho ho nts'etsopele ea dysfunction ea nonorganic.
LINKOTSO: basyatal amygdala; dopamine D1 receptor; dopamine D2 receptor; ho se sebetse hantle ha erectile dysfunction; mohlala oa rat
PMID: 30276840
DOI: 10.1111 / le.13160
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