Eur J Neurosci. 2016 Mar; 43 (5): 671-80. Doi: 10.1111 / ejn.13149. Epub 2016 Jan 13.
Naneix F1,2, Darlot F.1,2, Coutureau E1,2, Cador M1,2.
inahaneloang
Nako ea bocha ke nako e mahlonoko e khetholloang ke liphetoho tse kholo tsa neurobiological. Ho hlohlelletsa ho sa feleng hoa tsamaiso ea moputso ho ka ba karolo ea bohlokoa ea ho ba kotsing ea nts'etsopele ea pathological. Leha ho na le keketseho e makatsang ea tšebeliso ea lijo tse matlafatsang nakong ea bocha mekhatlong ea rona ea sejoale-joale, litlamorao tsa nako e telele tsa ho pepesetsoa ts'ebetso ea meputso ea boko li lula li sa utloisisehe. Mona, re fuputse lipapatsong litlamorao tsa nako e telele tsa tsoekere e ngata ka nako ea bocha ba bona ba bocha ba boela mekhoeng e metle ea meputso e monate. Likhoto tsa lilemong tsa bocha tse nang le phihlello e tsoelang pele ea tharollo ea suphose ea 5% (ho tloha matsatsing a morao-rao a 30-46) li bontšitse ho ja ho hoholo. Nakong ea ho ba motho e moholo (letsatsi la morao-rao la 70), ho sebelisa liteko tse sa lefelloeng tsa libotlolo tse peli, litoeba tse senotsoeng ke linate li bontšitse ho ja ho tlase ho feta likhoto tse sa senoloang tse fanang ka maikutlo a fokotsehileng a kutlo ea thepa e thabisang ea sucrose. Ho Teko ea 1, re lekile liteko tsa bona tse amanang le hedonic ho kenya kahare ho litharollo tse monate. Re bontšitse hore likhoto tse senotsoeng ka mokhoa o hlakileng li hlahisitse karabelo e nyane ka lebaka la litatso tse monate tse tlohelang ts'ebeliso ea metsi kapa quinine e sa phahamisoe. Kahoo, ho Teko ea 2, re hlokometse hore khaello ena ea hedonic e amana le maemo a tlase a polelo ea c-Fos ho li-nucleus accumbens, e leng karolo ea boko e tsejoang e le karolo ea mantlha ts'ebetsong ea hedonic. Liphumano tsena li bonts'a hore nalane ea ho ja ka mokhoa o phahameng nakong ea bocha e kenya liphoso tsa nako e telele kalafong ea hedonic e ka bakang mathata a amanang le moputso.
LINKOTSO: c-Fos; ho rata; tsamaiso ea maoto le matsoho; palatability; rat
PMID: 26762310
January 19, 2016
Ho ba le tsoekere e ngata haholo nakong ea bocha ba May Alter Brain's Circuits
Boithuto bo bocha ho likhoto bo ka fana ka leseli la bohlokoa ho litlamorao tsa nako e telele tsa tšebeliso e feteletseng ea lijo tse nang le tsoekere nakong ea bocha.
Phuputso e bonts'a hore thabo ea lijo tse joalo ha motho a se a le moholo ea fokotseha ho ba ileng ba li noa haholo bonyenyaneng. Bafuputsi ba fumane hore phokotso ena ea moputso e amana le ts'ebetso e fokotsehileng ho e 'ngoe ea libaka tsa bohlokoa tsa potoloho ea moputso ea boko, e bitsoang nucleus accumbens. Liphetoho tse joalo tse tšoarellang nako e telele li ka ba le litlamorao tsa bohlokoa bakeng sa mathata a amanang le moputso a joalo ka ts'ebeliso e mpe ea lithethefatsi kapa mathata a ho ja.
"Leha ho na le keketseho e makatsang ea tšebeliso ea lijo tse matlafatsang nakong ea bocha mekhatlong ea rona ea sejoale-joale, litlamorao tsa nako e telele joalo? European Journal of Neuroscience ho ithuta.
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