Ho lokolloa ha dopamine maemong a bethehileng a bakang papali ea chelete ba lahleheloang ke chelete. Linnet J, Peterson E, Doudet DJ, Gjedde A, Møller A. Acta Psychiatr Scand. 2010 Oct; 122 (4): 326-33. Setsi sa Neuroscience e Sebetsang, Univesithi ea Aarhus, Aarhus, Denmark. [imeile e sirelelitsoe]
Morero: Ho etsa lipatlisiso tsa neurotransmission ea dopaminergic mabapi le moputso oa chelete le kotlo ho papali ea chelete. Bacha ba papali ea chelete (PG) hangata ba tsoela pele ho becha leha ba lahlehetsoe, ho tsejoang e le ho 'lelekisa tahlehelo ea motho'.
Ka hona re ile ra nahana hore ho lahleheloa ke chelete ho ka tsamaisoa le ho lokolloa ha dopamine kahare ho phepelo ea PG ha ho bapisoa le taolo e phetseng hantle (HC).
MOTHA: Re sebelisitse Positron Emission Tomography (PET) ka [(11) C] raclopride ho lekanya tokollo ea dopamine ka har'a ventral striatum ea 16 PG le 15 HC e bapala Iowa Gask Task (IGT).
LITLHAKISO: PG ea lahleheloang ke chelete e ne e nyolisitse haholo tlhahiso ea dopamine ka hara leqheku le tlohang ka hare ha le bapisoa le HC. PG le HC ba hapileng chelete ba ne ba sa tšoane ho lokolloe ha dopamine.
TLHOKOMELISO: Seo re se fumaneng se fana ka maikutlo a hore dopaminergic e na le motheo oa tahlehelo ea chelete papaling ea papali ea chelete, e ka hlalosang boitšoaro bo lelekisang tahlehelo. Liphumano li ka ba le litlamorao ho utloisiseng ha dopamine dysfunctions le ho etsa liqeto tse sa lokang papaling ea papali ea chelete le lithethefatsi tse amanang le lithethefatsi.
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