Br J Psychiatry. 2015 Jun 4. pii: bjp.bp.114.152223.
Verdejo-Garcia A1, Clark L1, Verdejo-Román J1, Albein-Urios N1, Martinez-Gonzalez JM: Mosebetsi1, Gutierrez B1, Soriano-Mas C1.
inahaneloang
Background
Batho ba nang le lithethefatsi tsa koae le lithethefatsi tsa papali ea papali ea chelete ba bonts'a bofokoli ba ho fetoha ha kelello bo ka bang teng ka tlase ho boitšoaro bo kotsi.
Merero
Re ile ra etsa lipatlisiso tsa methapo e meng ea kutlo e sebelisang ts'ebeliso ea kelello ea batho ba sebelisang koae. V. genotyped bakeng sa polotorphism ea DRD18 / ANKK Taq18A.
Results
Basebelisi ba Cocaine le ba behang papali ea methapo ea methapo ba bonts'itse pontšo ea "collex" ea pele ho nako nakong ea phetoho. Basebelisi ba Cocaine ba ile ba boela ba bonts'a ts'ebetso ea ts'ebetso ea ts'ebetso ea methapo ea methapo ea methapo ea kutlo nakong ea mamello, mme ba fokotsa ts'ebetso ea ts'ebetso ea PFC e amanang le ho becha ha methapo ea methapo le taolo nakong ea ho fetoha. Lipatlisiso tsa pele tsa liphatsa tsa lefutso li bonts'itse hore basebelisi ba koae ba nkile mofuta oa DRD2 / ANKK Taq1A1 + genotype ba ka ba le litlamorao tse ikhethang tsa letšoao le fetohang le amanang le phetisetso ea PFC.
Nahanisisa
Ts'ebetso e fokotsoang ea ts'ebetso ea PFC ha e fetoha e ka ba letšoao le tloaelehileng la papali ea papali ea chelete le papali ea koae. Liphetho tse ling tse amanang le koae li amana le mokhoa o pharaletseng oa taolo e amanang le mosebetsi, e bonts'ang tlhekefetso ea matšoao ho dorsolateral le dmPFC.
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