Prog Neuropsychopharmacol Biol Psychiatry. 2017 Feb 4. pii: S0278-5846(16)30145-2.
doi: 10.1016 / j.pnpbp.2017.02.005.
Lee D1, Lee J1, Lee Lee1, Jung YC2.
inahaneloang
MORERO:
Mathata a lipapali tsa inthanete (IGD) ke mofuta oa boitšoaro bo hlephileng bo khetholloang ke taolo e sa tloaelehang ea bolaoli, e lebisang tahlehelong ea taolo ea papali e feteletseng. Khaello ea tlhokomelo le khatello ea maikutlo (ADHD) ke a mang a mathata a tloaelehileng a comorbid ho IGD, a amanang le nts'etsopele ea tsamaiso ea taolo e phahameng, e ka lebisang batho bokhobeng lipapaling. Re batlisitse tšusumetso ea bongoana ba ADHD holima likarolo tsa marang-rang tsa IGD.
LITLHAHISO:
Tlhahlobo ea ho nka litšoantšo tsa matla a khoheli a ho phomola e ile ea etsoa ho lithuto tse 44 tse nyane tsa banna tsa IGD tse nang le ADHD le ntle le bongoana le 19 e lumellanang le lilemo, taolo e nepahetseng ea banna. Khokahano e khethiloeng ea posterior cingulate cortex (PCC) e ile ea hlahlojoa ho lekola ho se ts'oanehe ha khokahano ea default mode network (DMN), e amanang le likhaello taolong ea phethahatso.
LIKOTSO:
Lithuto tsa IGD ntle le bongoana ADHD li bonts'itse khokahano e sebetsang e atolositsoeng (FC) lipakeng tsa libaka tse amanang le DMN (PCC, medial prefrontal cortex, thalamus) ha e bapisoa le taolo. Litaba tsena li boetse li bonts'a FC e atolositsoeng lipakeng tsa PCC le libaka tsa boko tse amehang ts'ebetsong ea masapo (anterior insula, orbitofrontal cortex) ha e bapisoa le lithuto tsa IGD tse nang le ADHD ea bongoana. Litaba tsa IGD tse nang le ADHD ea bongoana li bontšitse FC e atolositsoeng lipakeng tsa PCC le cerebellum (crus II), sebaka se amehang taolong ea phethahatso. Matla a khokahano lipakeng tsa PCC le cerebellum (crus II) a ne a hokahane hantle le likala tsa ho itlaleha tse bontšang ho se ts'oenyehe.
QETELLO:
Batho ka bomong ba nang le IGD ba bonts'itse FCC e thehiloeng ho PCC, litšobotsi tsa eona li kanna tsa itšetleha ka nalane ea ADHD ea bongoana. Liphuputso tsa rona li fana ka maikutlo a hore marang-rang a fetotsoeng a li-neural bakeng sa taolo ea phethahatso ho ADHD e ka ba mokhoa oa ho nts'etsapele IGD.
LINKOTSO: ADHD; Mokhoa o ikhethileng oa marang-rang; Mathata a ho bapala Inthaneteng; Khokahano e sebetsang ea mmuso oa phomolo; fMRI
PMID: 28174127
DOI: 10.1016 / j.pnpbp.2017.02.005
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