Tlhaho. 1998 May 21;393(6682):266-8.
Koepp MJ, Gunn RN, Lawrence AD, Cunningham VJ, Dagher A, Jones T, Brooks DJ, Bench CJ, Grasby PM.
mohloli o moholo
Yuniti ea cyclotron ea MRC, Sepetlele sa Hammersmith, London, UK.
inahaneloang
Dopaminergic neurotransication e kanna ea ameha ho ithuteng, ho matlafatseng boitšoaro, tlhokomelo le ho kopanya sensorimotor. Ho tlangoa ha radioligand 11C-e bitsoang li-raclopride ho dopamine D2 receptors e amehile ka maemo a endopele ea dopamine, e ka hlahisoang ke phephetso ea meriana. Mona re sebelisa sekhechana sa 11C-e ngotsoe lebitso la raclopride le positron emission tomography ho fana ka bopaki ba hore dopamine ea morao-rao e ntšoa ka har'a striatum ea motho nakong ea mosebetsi o tsamaisoang ka sepheo sa makoloi, e leng papali ea video. Ho tlama ha raclopride ho li-receptor tsa dopamine ka har'a striatum ho fokotsehile haholo nakong ea papali ea video ha ho bapisoa le maemo a motheo a ho tlama, ho lumellana le ho eketseha ha tlhahiso le ho tlama ha dopamine ho li-receptors tsa eona. Phokotso ea ho tlama ha raclopride ho striatum e tsamaellane hantle le boemo ba ts'ebetso nakong ea mosebetsi mme e ne e le kholo ka ho fetisisa ho ventral striatum. Liphetho tsena li bonts'a, tsebong ea rona bakeng sa lekhetlo la pele, maemo a boits'oaro ao dopamine e lokolloang bathong, mme a bonts'a bokhoni ba positron emission tomography ho bona li-fluxes tsa neurotransmitter ho vivo nakong ea boitšoaro bo feteletseng..
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