Behav Brain Res. 2013 Aug 1; 250: 257-63. Doi: 10.1016 / j.bbr.2013.05.022. Epub 2013 Mots'eanong 22.
mohloli o moholo
Setsi sa Saense ea Boko le Boitšoaro, Koleji ea Biotechnology, Xi'an University of Arts le Saense, Xi'an 710065, China. [imeile e sirelelitsoe]
inahaneloang
Li-receptor tsa Androgen li kenya letsoho taolong ea neuroendocrine ea boitšoaro ba monna ba thobalano, haholo-holo libakeng tsa boko tse teng tsamaisong ea methapo ea methapo. Tse tona tsa mefuta e mengata li fana ka tšitiso ea nako e telele ea boitšoaro ba thobalano kamora ho tsoaloa hangata, ho tsejoang e le satiety ea thobalano. Ho bontšitsoe ka likhoto hore polelo ea androgen receptor e fokotseha 24h kamora ho tsoaloa ka mokhoa o le mong, kapa ho ikamahanya le ho satiety, sebakeng sa medial preoptic, nucleus accumbens le ventromedial hypothalamus. Morero oa thuto ena e ne e le ho sekaseka lits'ebetso tsena ho phoofolo e 'ngoe, mandarin vole (Microtus mandarinus). Re bapisitse liphapang tsa androgen receptor (AR) le polelo ea testosterone (T) libakeng tse fapaneng tsa boko pakeng tsa li-mandarin voles tse satiate le tse pepesitsoeng ke basali ba amohelang empa ba sa lumelloe ho nyalana. Ho satiety ka tsa thobalano ho ne ho amahanngoa le polelo e fokotsehileng ea AR le T ho "lateral septal nucleus" (LS), medial amygdala (MeA), medial preoptic area (mPOA) le ventromedial hypothalamic nucleus (VMH). Tse tona tse pepesitsoeng ho basali ba amohelang li bonts'itse keketseho ea polelo ea AR le T moqomong oa bethe ea stria terminalis (BNST), LS, MeA le VMH. Litekanyetso tsa Serum testosterone li lula li sa fetohe kamora 24h ho banna ba pepesetsoeng basali ba amohelang kapa ba batona ba hlekefelitsoeng ho satiety. Lintlha tsena li fana ka maikutlo a kamano pakeng tsa ts'ebetso ea thobalano le ho fokotseha ha polelo ea AR le T libakeng tse itseng tsa boko, le kamano pakeng tsa tšusumetso ea thobalano le polelo e eketsehang ea AR le T libakeng tse ling tsa boko, ntle le maemo a testosterone
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